Effects of dietary supplementation with aluminum and citrate on iron metabolism in the rat

Biological Trace Element Research

Volumn 65, Issue 2, 1998, Pages 117-131

  Morgan, Evan H ^a   Redgrave, Trevor G ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Dietary aluminum; Dietary citrate; Iron deficiency; Iron metabolism; Iron overload

Indexed keywords

ALUMINUM; CITRIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; IRON DEFICIENCY; IRON METABOLISM; IRON OVERLOAD; LIPID PEROXIDATION; MALE; NONHUMAN; RAT;

ANIMALIA;

EID: 0032446762     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02784264     Document Type: Article

References (31)

1. J. B. Cannata, I. Fernández-Soto, M. J. Fernández-Menendez, J. L. Fernández-Martin, S. J. McGregor, J. H. Brock, et al., Role of iron metabolism in absorption and cellular uptake of aluminum, Kidney Int. 39, 799-803 (1991).
2. A. L. Florence, A. Gauthier, C. Ponsar, P. Van den Bosch de Aguilar, and R. R. Crichton, An experimental animal model of aluminum overload, Neurodegeneration 3, 315-323 (1994).
3. G. A. Trapp, Plasma aluminum is bound to transferrin, Life Sci. 33, 311-316 (1983).
4. M. Cochran, J. Coates, and S. Neoh, The competitive equilibrium between aluminium and ferric ions for the binding sites of transferrin, FEBS Lett. 176, 129-132 (1984).
5. 3+, Clin. Chem. 33, 405-407 (1987).
6. S. J. A. Fatemi, F. H. A. Kadir, and G. R. Moore, Aluminum transport in blood serum. Binding of aluminum to human transferrin in the presence of human albumin and citrate, Biochem. J. 280, 527-532 (1991).
7. R. B. Martin, The chemistry of aluminum as related to biology and medicine, Clin. Chem. 32, 1797-1806 (1986).
8. B. Halliwell and J. M. C. Gutteridge, Oxygen free radicals and iron relation to biology and medicine: some problems and concepts. Arch. Biochem. 246, 501-514 (1986).
9. R. S. Britton, A. S. Tavill, and B. R. Bacon, Mechanisms of iron toxicity, in Iron Metabolism in Health and Disease, J. H. Brock, J. W. Halliday, M. J. Peppard, and L. W. Powell, eds., Saunders, London, pp. 312-351 (1994).
10. J. M. C. Gutteridge, G. J. Quinlan, I. Clark, and B. Halliwell, Aluminum salts accelerate peroxidation of membrane lipids stimulated by iron salts, Biochim. Biophys. Acta 835, 441-447 (1985).
11. G. J. Quinlan, B. Halliwell, C. P. Moorhouse, and J. M. C. Gutteridge, Action of lead (II) and aluminum (III) ions on iron-stimulated lipid peroxidation in liposomes, erythrocytes and liver microsomel fractions, Biochim. Biophys. Acta, 962, 196-200 (1988).
12. C. X. Xie and R. A. Yokel, Aluminum facilitation of iron-mediated lipid peroxidation is dependent on substrate, pH, and aluminum and iron concentrations, Arch. Biochem. Biophys. 327, 222-226 (1996).
13. J. L. Greger, Aluminum metabolism, Annu. Rev. Nutr. 13, 43-63 (1993).
14. W. Frech and A. Cedergren, Aluminum concentrations in the brain and bone of rats fed citric acid, aluminum citrate or aluminium hydroxide, Food Chem. Toxicol. 22, 391-397 (1984).
15. T. S. Brown and R. Schwartz, Aluminum accumulation in serum liver and spleen of Fe-depleted and Fe-adequate rats. Biol. Trace Element Res. 34, 1-10 (1992).
16. C. A. Ecelbarger and J. L. Greger, Dietary citrate and kidney function affect aluminium, zinc and iron utilization in rats, J. Nutr. 121, 1755-1762 (1991).
17. M. Gillooly, T. H. Bothwell, J. D. Torance, A. P. McPhail, D. P. Derman, W. R. Bezwoda, et al. The effects of organic acids, phytakes and polyphenols on the absorption of iron from vegetables, Br. J. Nutr. 49, 331-342 (1983).
18. D. Ballot, R. D. Baynes, T. H. Bothwell, M. Gillooly, B. J. MacFarlane, A. P. Macphail, et al. The effects of fruit juices and fruits on the absorption of iron from a rice meal Br. J. Nutr. 57, 331-342, (1987).
19. M. Gardiner and E. H. Morgan, Transferrin and iron uptake by the liver in the rat, Aust. J. Exp. Biol. Med. Sci. 52, 723-736 (1974).
20. D. Trinder, E. Morgan, and E Baker, The effects of an antibody to the transferrin receptor and of rat serum albumin on the uptake of diferric transferrin by rat hepatocytes, Biochim. Biophys. Acta. 943, 440-446 (1988).
21. J. G. Bieri, G. S. Stoewsand, G. M. Briggs, R. M. Phillips, J. C. Woodward, and J. J. Knapka, Report on the American Institute of Nutrition ad hoc committee on standards for nutritional studies, J. Nutr. 107, 1340-1348 (1977).
22. H. A. Huebers, G. M. Brittenham, E. Csiba, and C. A. Finch, Absorption of carbonyl iron, J. Lab. Clin. Med. 108, 473-478 (1986).
23. E. Taylor, A. Crowe, and E. H. Morgan, Transferrin and iron uptake by the brain: effects of altered iron status, J. Neurochem. 57, 1584-1592 (1991).
24. International Committee for Standardization in Haematology, The measurement of total and insaturated iron-binding capacity in serum, Br. J. Haematol. 38, 281-290 (1978).
25. I. Kaldor, The measurement of non-haem tissue iron, Aust. J. Biol. 32, 795-800 (1954).
26. R. D. Crawford, Proposed role for a combination of citric acid and ascorbic acid in the production of dietary iron overload: a fundamental cause of disease, Biochem. Mol Med. 54, 1-11 (1995).
27. S. J. McGregor, M. L. Naves, R. Oria, J. K. Vass, and J. H. Brock, Effect of aluminum on iron uptake and transferrin receptor expression by human erythroleukaemia K562 cells, Biochem. J. 272, 377-382 (1990).
28. P. R. Dallman, M. A. Siimes, and E. C. Manies, Brain iron: persistent deficiency following short-term iron deprivation in the young rat. Br. J. Haematol. 31, 209-215 (1975).
29. D. Ben-Shachar, R. Ashbenazi, and M. B. H. Vondim, Long-term consequence of early iron-deficiency on dopaminergic neurotransmission in rats, Int. J. Dev. Neurosci. 4, 81-88 (1986).
30. A. C. G. Chua and E. H. Morgan, Effects of iron deficiency and iron overload on manganese uptake and deposition in the brain and other organs of the rat. Biol. Trace Element Res. 55, 39-54 (1996).
31. W. A. Jefferies, M. R. Brandon, S. V. Hunt, A. F. Williams, K. C. Gatter, and D. Y. Mason, Transferrin receptor on endothelium of brain capillaries, Nature 312, 161-163 (1984).