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Volumn 23, Issue SUPPL. 5, 1998, Pages 681-699

A one-month repeated oral dose toxicity study of methotrexate in unilaterally nephrectomized rats

Author keywords

Methotrexate; Nephrectomized Rat; One month toxicity

Indexed keywords

7 HYDROXYMETHOTREXATE; ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; CALCIUM; CHOLESTEROL; CREATININE; GLUCOSE; METHOTREXATE; NITROGEN; PHOSPHATE; PROTEIN; TRIACYLGLYCEROL;

EID: 0032444808     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.23.supplementv_681     Document Type: Article
Times cited : (11)

References (11)
  • 1
    • 0023735704 scopus 로고
    • Methotrexate kinetics in rheumatoid arthritis: Is there an interaction with nonsteroidal antiinflammatory drugs?
    • Ahern, M., Booth, J., Loxton, A., McCarthy, P. and Kevat, S. (1988) : Methotrexate kinetics in rheumatoid arthritis: is there an interaction with nonsteroidal antiinflammatory drugs? J. Rheumatol., 15, 1356-1360.
    • (1988) J. Rheumatol. , vol.15 , pp. 1356-1360
    • Ahern, M.1    Booth, J.2    Loxton, A.3    McCarthy, P.4    Kevat, S.5
  • 2
    • 0027430733 scopus 로고
    • Effects of age at the time of unilateral nephrectomy and dietary protein on long-term renal function in rats
    • Baudoin, P. and Provoost, A.P. (1993) : Effects of age at the time of unilateral nephrectomy and dietary protein on long-term renal function in rats. Pediatr. Nephrol., 7, 536-542.
    • (1993) Pediatr. Nephrol. , vol.7 , pp. 536-542
    • Baudoin, P.1    Provoost, A.P.2
  • 3
    • 0017873070 scopus 로고
    • The clinical pharmacology of methotrexate. New applications of an old drug
    • Bleyer, W.A. (1978) : The clinical pharmacology of methotrexate. New applications of an old drug. Cancer, 41, 36-51.
    • (1978) Cancer , vol.41 , pp. 36-51
    • Bleyer, W.A.1
  • 4
    • 0024331184 scopus 로고
    • Dose-dependent pharmacokinetics of methotrexate and 7-hydtxymethotrexate in the rat in vivo
    • Bremnes, R.M., Slørdal, L., Wist, E. and Aarbakke, J. (1989) : Dose-dependent pharmacokinetics of methotrexate and 7-hydtxymethotrexate in the rat in vivo. Cancer Res. 49, 6359-6364.
    • (1989) Cancer Res. , vol.49 , pp. 6359-6364
    • Bremnes, R.M.1    Slørdal, L.2    Wist, E.3    Aarbakke, J.4
  • 5
    • 0017355433 scopus 로고
    • Hepatotoxicity in Wistar rats following chronic methotrexate administration: A model of human reaction
    • Custer, R.P., Freeman-Narrod, M. and Narrod, S.A. (1977) : Hepatotoxicity in Wistar rats following chronic methotrexate administration: a model of human reaction. J. Natl. Cancer Inst., 58, 1011-1017.
    • (1977) J. Natl. Cancer Inst. , vol.58 , pp. 1011-1017
    • Custer, R.P.1    Freeman-Narrod, M.2    Narrod, S.A.3
  • 6
    • 0024498462 scopus 로고
    • Pharmacokinetics of methotrexate (MTX) and 7-hydroxymethotrexate (7-OH-MTX) in rats and evidence for the metabolism of MTX to 7-OH-MTX
    • Fahrig, L., Brasch, H. and Iven, H. (1989) : Pharmacokinetics of methotrexate (MTX) and 7-hydroxymethotrexate (7-OH-MTX) in rats and evidence for the metabolism of MTX to 7-OH-MTX. Cancer Chemother. Pharmacol. 23, 156-160
    • (1989) Cancer Chemother. Pharmacol. , vol.23 , pp. 156-160
    • Fahrig, L.1    Brasch, H.2    Iven, H.3
  • 8
    • 3242855023 scopus 로고
    • The action of 4-amino-N10-methylpteroylglutamic acid in mice, rats, and dogs
    • Ferguson, F.C. Jr., Thiersch, J.B. and Philips, F.S. (1950) : The action of 4-amino-N10-methylpteroylglutamic acid in mice, rats, and dogs. J. Pharmacol., 98, 293-299.
    • (1950) J. Pharmacol. , vol.98 , pp. 293-299
    • Ferguson Jr., F.C.1    Thiersch, J.B.2    Philips, F.S.3
  • 9
    • 0003130095 scopus 로고
    • Statistics for toxicologists
    • (Hayes, A.W., ed.), 3rd ed., Raven Press, New York
    • God, S.C. and Weil, C.S. (1994): Statistics for toxicologists. In Principles and Methods of Toxicology (Hayes, A.W., ed.), 3rd ed., PP. 230-237, Raven Press, New York.
    • (1994) Principles and Methods of Toxicology , pp. 230-237
    • God, S.C.1    Weil, C.S.2
  • 10
    • 0015380324 scopus 로고
    • Methotrexate toxicity: Correlation with duration of administration, plasma levels, dose and excretion pattern
    • Goldie, J.H., Price, L.A. and Harrap, K.R. (1972) : Methotrexate toxicity: correlation with duration of administration, plasma levels, dose and excretion pattern. Europ. J. Cancer 8, 409-414.
    • (1972) Europ. J. Cancer , vol.8 , pp. 409-414
    • Goldie, J.H.1    Price, L.A.2    Harrap, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.