Impact of resting and ischemic blood flow on infarct probability in ischemic preconditioning - A new approach to infarct size-blood flow data by logistic regression

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 12, 1998, Pages 2719-2728

  Post, Heiner ^a   Schulz, Rainer ^a   Vahlhaus, Christian ^a   Hüsing, Johannes ^a   Hirche, Herbert ^a   Gallagher, Kim P ^b   Heusch, Gerd ^a,c  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b PFIZER INC   (United States)

^c UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Ischemic preconditioning; Microspheres; Miocardial infarction; Regional myocardial blood flow

Indexed keywords

ENFLURANE; MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DATA ANALYSIS; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; REGRESSION ANALYSIS; REST; RETROSPECTIVE STUDY; SWINE;

ANIMALIA; SUS SCROFA;

EID: 0032444675     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0836     Document Type: Article

References (27)

1. AUSTIN RE, ALDEA GS, COGGINS DL, FLYNN AE, HOFFMAN JIE, 1990. Profound spatial heterogeneity of coronary reserve. Discordance between patterns of resting and maximal myocardial blood flow. Circ Res 67: 319-331.
2. BASSINGTHWAIGHTE JB, MALONE MA, MOFFETT TC, KING RB, LITTLE SE, LINK JM, KROHN KA, 1987. Validity of microsphere depositions for regional myocardial flows. Am J Physiol 253: H184-H193.
3. BISHOP SP, WHITE FC, BLOOR CM, 1976. Regional myocardial blood flow during acute myocardial infarction in the conscious dog. Circ Res 38: 429-438.
4. BUCKBERG GD, LUCK JC, PAYNE DB, HOFFMAN JIE, ARCHIE JP, FIXLER DE, 1971. Some sources of error in measuring regional blood flow with radioactive microspheres. J Appl Physiol 31: 598-604.
5. COGGINS DL, FLYNN AE, AUSTIN JR. RE, ALDEA GS, MUEHRCKE D, GOTO M, HOFFMAN JIE, 1990. Nonuniform loss of regional flow reserve during myocardial ischemia in dogs. Circ Res 67: 253-264.
6. FRANZEN D, CONWAY RS, ZHANG H, SONNENBLICK EH, ENG C, 1988. Spatial heterogeneity of local blood flow and metabolic content in dog hearts. Am J Physiol 254: H344-H353.
7. GHALEH B, SHEN Y-T, VATNER SF, 1996. Spatial heterogeneity of myocardial blood flow presages salvage versus necrosis with coronary artery reperfusion in conscious baboons. Circulation 94: 2210-2215.
8. GROSS GJ, AUCHAMPACH JA, 1992. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ Res 70: 223-233.
9. KING RB, BASSINGTHWAIGHTE JB, HALES JRS, ROWELL LB, 1985. Stability of heterogeneity of myocardial blood flow in normal awake baboons. Circ Res 57: 285-295.
10. KLEINBAUM D, 1994. Logistic regression. A self-learning text, Springer Verlag, New York.
11. LIANG KY, ZEGER SL, 1986. Longitudinal data analysis using generalized linear models. Biometrika 73: 13-22.
12. MCCULLACH P, NELDER JA, 1989. Generalized Linear Models. Chapman and Hall, London, New York, pp. 124-128.
13. MURDOCK RH, CHU A, GRUBB M, COBB FR, 1985. Effects of reestablishing blood flow on extent of myocardial infarction in conscious dogs. Am J Physiol 18: H783-H791.
14. MURRY CE, JENNINGS RB, REIMER KA, 1986. Pre-conditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136.
15. OVIZE M, KLONER RA, HALE SL, PRZYKLENK K, 1992. Coronary cyclic flow variations "precondition" ischemic myocardium. Circulation 85: 779-789.
16. PRZYKLENK K, BAUER B, OVIZE M, KLONER RA, WHITTAKER P, 1993. Regional ischemic "Preconditioning" protects remote virgin myocardium from subsequent sustained coronary occlusion. Circulation 87: 893-899.
17. REIMER KA, JENNINGS RB, 1979. The "waveront phenomenon" of myocardial ischemic cell death. II. Transmural progression of necrosis within the framework of ischemic bed size (myocardium at risk) and collateral flow. Lab Invest 40: 633-644,
18. RIVAS F, COBB FR, BACHE RJ, GREENFIELD JR. JC, 1976. Relationship between blood flow to ischemic regions and extent of myocardial infarction. Serial measurement of blood flow to ischemic regions in dogs. Circ Res 38: 439-447.
19. SAVAGE RM, GUTH BD, WHITE FC, HAGAN AD, BLOOR CM, 1981. Correlation of regional myocardial blood flow and function with myocardial infarct size during acute myocardial ischemia in the conscious pig. Circulation 64: 699-707.
20. SCHULZ R, MIYAZAKI S, MILLER M, THAULOW E, HEUSCH G, ROSS JR. J, GUTH BD, 1989. Consequences of regional inotropic stimulation of ischemic myocardium on regional myocardial blood flow and function in anesthetized swine. Circ Res 64: 1116-1126.
21. SCHULZ R, POST H, VAHLHAUS C, HEUSCH G, 1998. Ischemic preconditioning in pigs - a graded phenomenon: its relation to adenosine and bradykinin. Circulation 98: 1022-1029.
22. SCHULZ R, ROSE J, HEUSCH G, 1994. Involvement of activation of ATP-dependent potassium channels in ischemic preconditioning in swine. Am J Physiol 267: H1341-H1352.
23. SKYSCHALLY A, SCHULZ R, HEUSCH G, 1993. Cordat II: A new program for data acquisition and on-line calculation of hemodynamic and regional myocardial dimension parameters. Comput Biol Med 23: 359-367.
24. SONNTAG M, DEUSSEN A, SCHULTZ J, LONCAR R, HORT W, SCHRADER J, 1996. Spatial heterogeneity of blood flow in the dog heart. I. Glucose uptake, free adenosine and oxidative/glycolytic enzyme activity. Pflügers Arch 532: 439-450.
25. VATNER SF, PATRICK TA, KNIGHT DR, MANDERS WT, FALLON JT, 1988. Effects of calcium channel blocker on responses of blood flow, function, arrhythmias, and extent of infarction following reperfusion in conscious baboons. Circ Res 62: 105-115.
26. YAO Z, GROSS GJ, 1993. Role of nitric oxide, muscarinic receptors, and the ATP-sensitive K+ channel in mediating the effects of acetylcholine to mimic pre-conditioning in dogs. Circ Res 73: 1193-1201.
27. YIPINTSOI T, DOBBS WA, SCANLON PD, KNOPP TJ, BASSING-THWAIGHTE JB, 1973. Regional distribution of diffusible tracers and carbonized microspheres in the left ventricle of isolated dog hearts. Circ Res 33: 573-587.