Neonatal reversible focal cerebral ischemia: A new model

Neuroscience Research

Volumn 32, Issue 4, 1998, Pages 349-353

  Derugin, Nikita ^a   Ferriero, Donna M ^a   Vexler, Zinaida S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Middle cerebral artery occlusion; Neonate; Reversible cerebral ischemia; Stroke; TTC

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; DISEASE MODEL; FEMALE; HISTOLOGY; MIDDLE CEREBRAL ARTERY OCCLUSION; NEWBORN; NEWBORN DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; ANIMALS, NEWBORN; BRAIN ISCHEMIA; CEREBRAL ARTERIES; DISEASE MODELS, ANIMAL; FEMALE; LIGATION; RATS; RATS, SPRAGUE-DAWLEY; SUTURE TECHNIQUES;

EID: 0032444634     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(98)00096-0     Document Type: Article

References (19)

1. Ashwal S., Cole D.J., Osborne S., Osborne T.N., Pearce W.J. A new model of neonatal stroke: reversible MCA occlusion in the rat pup. Pediatr. Neurol. 12:1995;191-196.
2. Cheng Y., Desmukh M., D'Costa A., Demaro J., Gidday J., Shan A., Sun Y., Jacquin M., Jonson E., Holtzman D. Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. J. Clin. Invest. 101:1998;1-8.
3. Duverger D., MacKenzie E. The quantification of cerebral infarction following focal ischemia in the rat: influence of strain, arterial pressure, blood glucose concentration, and age. J. Cereb. Blood Flow Metab. 8:1988;449-461.
4. Ferrer I., Pozas E., Lopez E., Ballabriga J. Bcl-2, Bax and Bcl-x expression following hypoxia-ischemia in the infant rat brain. Acta Neuropathologica. 94:1997;583-589.
5. Koelfen W., Freund M., Varnholt V. Neonatal stroke involving the middle cerebral artery in term infants: clinical presentation EEG and imaging studies and outcome. Dev. Med. Child Neurol. 37:1995;204-212.
6. Koizumi J., Yoshida Y., Nakazava T., Ooneda J. Experimental studies of ischemic brain edema. 1. A new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn. J. Stroke. 8:1986;1-8.
7. Kucharczyk J., Vexler Z., Roberts T.P., Asgari H., Derugin N., Moseley M. Echo planar perfusion-sensitive imaging of acute cerebral ischemia. Radiology. 188:1993;711-717.
8. Levine S. Anoxic-ischemic encephalopathy in rats. Am. J. Pathol. 36:1960;1-17.
9. Longa E.Z., Weinstain P.R., Carlson S., Cumming R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 20:1989;84-91.
10. McDonald J.W., Johnston M.V. Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Res. Reviews. 15:1990;41-70.
11. McIlwain H., Bachelard H.S. Chemical and enzymatic make-up of the brain during development and ageing. Wilkins, Wa Biochemistry and the central nervous system. 1971;371-412 The Williams and Wilkins Company, Baltimore, MD.
12. Muramatsu K., Fukuda A., Togari H., Wada Y., Nishino H. Vulnerability to cerebral hypoxic-ischemic insult in neonatal but not in adult rats is in parallel with disruption of the blood-brain barrier. Stroke. 28:1997;2281-2288.
13. Nehlig A., de Vasconcelos A.P., Boyet S. Postnatal changes in local cerebral blood flow measured by the quantitative autoradiographic [14C] iodoantipurine technique in freely mooving rats. J. Cereb. Blood Flow Metab. 9:1989;579-588.
14. Palmer C. Hypoxic-ischemic encephalopathy: therapeutic approaches against microvascular injury, and the role of neturophils, PAF and free radicals. Clin. in Perinatol. 22:1995;481-517.
15. Rice J.E., Vannucci R.C., Brierley J.B. The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann. Neurol. 9:1981;131-141.
16. Roohey T., Raju T.N., Moustogiannis A.N. Animal models for the study of perinatal hypoxic-ischemic encephalopathy: a critical analysis. Early Human Dev. 47:1997;115-146.
17. Vannucci R.C., Christensen M.A., Stein D.T. Regional cerebral glucose utilization in the immature rat: effect of hypoxia-ischemia. Pediatr. Res. 26:1989;208-214.
18. Vexler Z.S., Roberts T.P.L., Derugin N., Bollen A., Arieff A.I., Kucharczyk J. Transient cerebral ischemia: association of apoptosis induction with hypoperfusion. J. Clin. Invest. 99:1997;1453-1459.
19. Yager J.Y., Thornhill J.A. The effect of age on susceptibility to hypoxic-ischemic brain injury. Neurosci. Biobehav. Reviews. 21:1997;167-174.