Growth inhibition and activation of apoptotic gene expression by human chorionic gonadotropin in human breast epithelial cells

Anticancer Research

Volumn 18, Issue 6 A, 1998, Pages 4003-4010

  Srivastava, Pramod ^a   Russo, Jose ^a   Mgbonyebi, Ozuem P ^a   Russo, Irma H ^a  

^a FOX CHASE CANCER CENTER   (United States)

Author keywords

Apoptosis; Breast epithelium; hCG; Human; Programmed cell death; Proliferation

Indexed keywords

BENZO[A]PYRENE; CHORIONIC GONADOTROPIN; PROTEIN BAX; PROTEIN P21; PROTEIN P53; RNA; TRANSFORMING GROWTH FACTOR BETA;

APOPTOSIS; ARTICLE; BREAST EPITHELIUM; CELL CYCLE; CELL GROWTH; CELL TRANSFORMATION; CELL VIABILITY; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; NORTHERN BLOTTING; PRIORITY JOURNAL;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BENZO(A)PYRENE; BREAST; CELL DIVISION; CELL LINE, TRANSFORMED; CELLS, CULTURED; CHORIONIC GONADOTROPIN; CLUSTERIN; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; GENES, MYC; GENES, P53; GENES, TUMOR SUPPRESSOR; GLYCOPROTEINS; HUMANS; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, LH; TRANSFORMING GROWTH FACTOR BETA; UROTHELIUM;

EID: 0032442701     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Simpson ER, and MacDonnald PC: Endocrine physiology of the placenta. Annu Rev Physiol 43: 163-188, 1981.
2. Russo IH, Koszalka M, and Russo J: Human chorionic gonadotropin and rat mammary cancer prevention. J Natl Cancer Inst 82: 1286-1289, 1990.
3. Russo J and Russo IH: Toward a physiological approach to breast cancer prevention. Cancer Epidemiol Biomarkers & Prevention 3: 353-364, 1994.
4. Tay LK and Russo J: Effect of human chorionic gonadotropin on 7,12-dimethylbenz(a)anthracene-induced DNA binding and repair synthesis by rat mammary epithelial cells. Chem-Biol Interact 55: 13-21, 1985.
5. Russo IH, Koszalka M and Russo J: Effect of human chorionic gonadotropin on mammary gland differentiation and carcinogenesis. Carcinogenesis 11: 1849-1855, 1990.
6. Russo IH, Koszalka M and Russo J: Protective effect of chorionic gonadotropin on DMBA-induced mammary carcinogenesis. Br J Cancer 62: 243-247 1990.
7. Srivastava P, Russo IH and Russo J: Chorionic gonadotropin inhibits rat mammary carcinogenesis through activation of programmed cell death. Carcinogenesis 11: 1799-1808, 1997.
8. Alvarado ME, Alvarado NE, Russo J and Russo IH: Human chorionic gonadotropin inhibits proliferation and induces expression of inhibin in human breast epithelial cells in vitro. In Vitro 30A: 4-8, 1994.
9. Ronai Z, Tillotson JK, Trganos F, Darzynkiewixz Z, Conaway CC, Upadhyaya P, El- Bayoumy K: Effects of organic and inorganic selenium compounds on rat mammary tumor cells. Int J Cancer 63: 428-434, 1995.
10. Buscail L, Esteve J, Saint-Laurent N, Bertrand V, Reisine T, O'Carroll A, Bell GI, Schally AV, Vaysse N and Susini C: Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 analogue SSTR5 through different mechanisms, Proc Natl Acad Sciences 92: 1580-1584, 1995.
11. Lockshin RA, Zakeri Z: The biology of cell death and its relationship to aging. In: Holbrook NJ, Martin GR, Lockshin RA (eds) Cellular aging and cell death. Wiley- Liss, Inc. New York, 1996, pp167-180.
12. Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ and Hancock C: Induction of apoptosis in Fibroblasts by c-myc protein. Cell 69: 119-128, 1993.
13. Marx J: Cell death studies yield cancer clues. Science 259: 760-761, 1993.
14. Yuan J and Horvitz HR: The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev Biol 138: 33-41, 1990.
15. Hengartner MO and Horovitz HR: C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl2. Cell 76: 665-676, 1994.
16. Yuan J, Shaham S, Leduox S, Ellis HM and Horvitz HR: The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75: 641-652, 1993.
17. Nicholson DW, Ali A, Thornberry NA, Vailancourt JP, Ding CK, Gareau Y, Griffin PRL, Labelle M, Lazebnik YAY, Griffin PRL, Labelle M, Lazebnik YA, Munday NA, Raju SM, Smulson ME, Yamin T-T, Yu VL and Miller DK: Identification and inhibition of the ICE/ced-3 protease necessary for mammalian apoptosis. Nature 376: 37-43, 1995.
18. Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS and Dixit VM: Yama/CPP32, a mammalian homolog of CED-3, is a Crm A-inhibitable protease that cleaves the death substrate poly(ADP-Ribose) polymerase. Cell 81: 801-809, 1995.
19. Fernandes-Alnemri T, Takashi A, Armstrong R, Krebs J, Fritz L, Tommaselli KJ, Wang L, Yu Z, Croce C M, Salveson G, Earnshaw W C, Litwack G and Alnemri ES: Mch3, a novel human apoptotic cysteine protease highly related to CPP32. Cancer Res 55: 6045-6052, 1995.