Synthesis and biological evaluation of (23R)- and (23S)-24,24-difluoro 1α,23,25-trihydroxyvitamin D3

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 12, 1998, Pages 1932-1935

  Iwasaki, Hiroshi ^a   Miyamoto, Yoichi ^a   Hosotani, Ryuzo ^a   Nakano, Yoshio ^a   Konno, Katsuhiro ^b   Takayama, Hiroaki ^b  

^a NOF Corporation   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

24,24 difluoro 1 ,23,25 trihydroxyvitamin D3; Binding assay; HL 60 cell differentiation; Modified Mosher method; Reformatsky reaction; Vitamin D analog

Indexed keywords

24,25 DIFLUORO 1ALPHA,23,25 TRIHYDROXYVITAMIN D3; COLECALCIFEROL DERIVATIVE; UNCLASSIFIED DRUG; VITAMIN D BINDING PROTEIN; VITAMIN D RECEPTOR;

ARTICLE; CELL PROLIFERATION; CHEMICAL REACTION; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 0032442294     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.1932     Document Type: Article

References (2)

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2. Campbell M. J., Koeffler H. P., J. Natl. Cancer Inst., 89, 182-185 (1997).