Inhibition of protein synthesis by zinc: Comparison between protein synthesis and RNA synthesis

Human and Experimental Toxicology

Volumn 17, Issue 12, 1998, Pages 661-667

  Walther, Udo Ingbert ^a   Schulze, Johannes ^a   Forth, Wolfgang ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Protein synthesis inhibition; RNA synthesis inhibition; Zinc toxicity

Indexed keywords

AMANITIN; AMINO ACID; DACTINOMYCIN; PROTEIN; RNA; URIDINE; ZINC;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL CULTURE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; HUMAN; HUMAN CELL; INHALATION; LUNG ALVEOLUS CELL; LUNG ALVEOLUS CELL TYPE 2; LUNG FIBROBLAST; LUNG TOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; RAT; RESPIRATORY DISTRESS; RNA SYNTHESIS;

AMANITINS; AMINO ACIDS; ANIMALS; CELLS, CULTURED; DACTINOMYCIN; FIBROBLASTS; HUMANS; LUNG; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RATS; RNA; TIME FACTORS; TUMOR CELLS, CULTURED; URIDINE; ZINC;

ANIMALIA;

EID: 0032441535     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/096032798678908116     Document Type: Article

References (28)

1. Vallee BL, Falchuk KH. The biochemical basis of zinc physiology. Physiol Rev 1993; 73: 79-118.
2. Prasad AS. Zinc: an overview. Nutrition 1995; 11 (suppl): 93-99.
3. Ripa S, Ripa R. Zinc cellular traffic: Physiopathological considerations. Minerva Med 1995; 86: 37-43.
4. Pare CMB, Sandier M. Smoke-bomb pneumonitis: description of a case. J Roy Marmy Med Corps 1954; 100: 320-322.
5. Milliken JA, Waugh D, Kadish ME. Acute interstitial pulmonary fibrosis caused by a smoke bomb. Can Med Ass J 1963; 88: 36-39.
6. Weser U, Seeber S, Warnecke P. Zur Wirkung von Zn2+ auf die Nukleinsäurebiosynthese von Aszites-Turmorzellen. Experientia 1969; 25: 489-490.
7. Hatayama T et al. Characteristic induction of 70,000 da-heat shock protein and metallothionein by zinc in HeLa cells. Mol Cell Biochem 1992; 112: 143-153.
8. Wataha JC, Hanks CT, Craig RG. In vitro effects of metal ions on cellular metabolism and the correlation between these effects and the uptake of the ions. J Biomed Mater Res 1994; 28: 427-433.
9. Provinciali M, Di Stefano G, Fabris N. Dose-dependent opposite effect of zinc on apoptosis in mouse thymocytes. Int J Immunopharmacol 1995; 17: 735-744.
10. Masuda Y et al. Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells. Leuk Res 1995; 19: 549-556.
11. Smith JB et al. Transmembrane signals and protooncogene induction evoked by carcinogenic metals and prevented by zinc. Environ Health Perspect 1994; 102(Suppl. 3): 181-189.
12. Hernandez J et al. Interactions between metallothionein inducers in rat liver and primary cultures of rat hepatocytes. Chem Biol Interact 1996; 100: 27-40.
13. Bicknell GR, Snowden RT, Cohen GM. Formation of high molecular mass DNA fragments is a marker of apoptosis in hte human leukaemic cell line, U937. J Cell Sci 1994; 107: 2483-2489.
14. Walther UI et al. Inhibition of RNA synthesis in cultured lung cells exposed to zinc chloride. Arch Pharmacol 1995; 354(4 Suppl. 1): R20.
15. Walther UI et al. Effect of elevated zinc chloride concentrations on protein synthesis in human lung cells. In vitro Toxicol 1997; 10: 195-206.
16. Freshney RI. Cultures of animal cells. A manual of basic technique. Alan R. Liss, Inc. New York 1987.
17. Read SM, Northcote DH. Minimization of variation in the response to different proteins of the Coomassie Blue G dye-binding assay for protein. Anal Biochem 1981; 116: 53-64.
18. Failla ML, Cousins RJ. Zinc accumulation and metabolism in primary cultures of adult rat liver cells. Biochim Biophys Acta 1978; 543: 293-304.
19. Steinebach OM, Wolterbeek HT. Effects of zinc on rat hepatoma HTC cells and primary cultured rat hepatocytes. Toxicol Appl Pharmacol 1993; 118: 245-254.
20. Kanemaru Y et al. Effect of caffeine and zinc on DNA and protein synthesis of neonatal rat cardiac muscle cell in culture. Res Exp Med Berl 1992; 192: 115-122.
21. Frazier JM. Multiple endpoint measurements to evaluate the intrinsic cellular toxicity of chemicals. In Vitro Toxicol 1990; 3: 349-358.
22. Taylor GA, Blackshear PJ. Zinc inhibits turnover of labile mRNAs in intact cells. J Cell Physiol 1995; 378-387.
23. Hashizume M, Yamaguchi M. Stimulatory effect of beta-alanyl-L-histidinato zinc on cell proliferation is dependent on protein synthesis in osteoblastic MC3T3-E1 cells. Mol Cell Biochem 1993; 122: 5964.
24. Tate DJ et al. Influence of zinc on selected cellular functions of cultured human retinal pigment epithelium. Curr Eye Res 1995; 14: 897-903.
25. Brandao Neto J et al. Endocrine interaction between zinc and prolactin. An interpretative review. Biol Trace Elem Res 1995; 49: 139-149.
26. Shimokawa N, Yamaguchi M. Characterization of bone protein components with polyacrylamide gel electrophoresis: Effects of zinc and hormones in tissue culture. Mol Cell Biochem 1992: 117: 153-158.
27. Palmiter RD. Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active-transcription factor, MTF-1. Proc Natl Acad Sci USA 1994; 91: 1219-1222.
28. Takano Y, Okudaira M, Harmon BV. Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate. Path Res Pract 1993; 189: 197-203.