A porcine model for investigation of hyperthermic isolated liver perfusion

Journal of Investigative Surgery

Volumn 11, Issue 6, 1998, Pages 401-408

  Lang, H ^a   Nadalin, S ^a,b   Thyen, A ^a   Moreno, L ^a   Shehata, S R ^a   Schuttler W ^a   Oldhafer, K J ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Ital Association of Cancer Research

Author keywords

Animal model; Hyperthermia; Isolated liver perfusion

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LACTIC ACID; LIVER ENZYME; OXYPOLYGELATIN; RINGER SOLUTION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTERY BLOOD FLOW; ARTICLE; BLOOD; COMPLICATION; FEMALE; HEPATIC ARTERY; HYPERTHERMIC THERAPY; ISOLATED LIVER; LACTATE BLOOD LEVEL; LIVER BLOOD FLOW; LIVER PARENCHYMA; LIVER PERFUSION; NONHUMAN; PORTAL VEIN; PORTAL VEIN BLOOD FLOW; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; SWINE; TEMPERATURE;

EID: 0032440855     PISSN: 08941939     EISSN: None     Source Type: Journal    
DOI: 10.3109/08941939809032217     Document Type: Article

References (16)

1. Healey JE, Smith JL, Clark RL, Stehlin JS, White EC. Hepatic tissue tolerance to thio-TEPA administered by the isolation-perfusion technique. J Surg Res. 1961;1:111-116.
2. Shingleton WW, Parker Rt, Mahaley S. Abdominal perfusion for cancer chemotherapy. Ann Surg. 1960;152:583-593.
3. Sindelar WF. Method of isolation-perfusion of the liver in the pig. Am Surg. 1984;50:557-563.
4. Skibba JL, Condon RE. Hyperthermic isolation-perfusion in vivo of the canine liver. Cancer. 1983;51:1303-1309.
5. Fajardo LF, et al. Effects of hyperthermia in a malignant tumor. Cancer. 1980;45:613-623.
6. Giovanella, et al. Selective lethal effect of supranormal temperatures on human neoplastic cells. Cancer Res. 1976;36:3944-3950.
7. Zoedler T, Braaasch D, Becker H, Ebener C, Röher HD. Perfusionhyperthermie der Leber bei Schweinen-Darstellung eines Verfahrens zur präzisen Steuerung der extremen Hypertherrmie. Onkologie. 1990;13:381-386.
8. Boddie AW, Booker L, Mullins JD, Buckley CJ, McBride CM. Hepatic hyperthermia by total isolation and regional perfusion in vivo. J Surg Res. 1979;26:447-457.
9. Sindelar WF. Isolation-perfusion of the liver with 5-fluorouracil. Ann Surg. 1985;201:337-343.
10. Horikawa M, Nakajima Y, Kido K, Ko S, Ohashi K, Nakano H. Simple method of hyperthermo-chemo-hypoxic isolated liver perfusion for hepatic metastases. World J Surg. 1994;18:845-851.
11. Van de Velde CJH, Kothuis BJL, Barenbrug HWM, Jongejan N, Runia RD, De Braw LM, Zwaveling A. A successful technique of in vivo isolated liver perfusion in pigs. J Surg Res. 1986;41:593-599.
12. Adam R, Poggi L, Capron M, Morin J, Gigou M, Miramand JC, Szekely AM, Houssin D. Asanguineous isolated hyperthermic in vivo perfusion of the liver in the rat. Eur Surg Res. 1987;19:366-374.
13. Skibba JL, Almagro UA, Condon RE, Petroff RJ. A technique for isolation perfusion of the canine liver with survival. J Surg Res. 1983;34:123-132.
14. Lang H, Nadalin S, Moreno L, Thyen A, Shehata SR, Flemming P, Oldhafer KJ, Pichlmayr R. Asanguineous isolated hyperthermic perfusion of the liver - Results of an experimental study in pigs. In: Oldhafer KJ, Lang H, Pichlmayr R, eds. Isolated Liver Perfusion for Hepatic Tumors. Berlin: Springer Verlag; Recent Results in Cancer Research, Vol. 147, S. 19-27.
15. Bredt M, Kraus T, Mehrabi A, Gebhard MM, Herfarth C, Klar E. TNF-und Endothelin Konzentrations-Kinetik während normothermer Leberischämie und Reperfusion - Hinweise auf potentiell protektive Funktion erhöhter TNF-Spiegel. Langenbecks Arch Chir. 1997;Suppl 2:681-685.
16. Oldhafer KJ, Lang H, Frerker M, Moreno L, Chavan A, Flemming P, Nadalin S, Schmoll E, Pichlmayr R. First experience and technical aspects of isolated liver perfusion for extensive liver metastases. Surgery. 1998;123:622-631.