The accumulation and histological effects of organometallic fungicides Propineb and Maneb in the kidneys of fetus and female rats during pregnancy

Toxicology Letters

Volumn 99, Issue 2, 1998, Pages 91-98

  Guven, Kemal ^a   Deveci, Engin ^a   Akba, Osman ^a   Onen, Abdurrahman ^a   De Pomerai, David ^b  

^a DICLE UNIVERSITY   (Turkey)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Fungicide; Histopathological effects; Kidney; Maneb; Maternal fetal metal accumulation; Propineb

Indexed keywords

MANEB; PROPINEB;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATOMIC EMISSION SPECTROMETRY; BIOACCUMULATION; CONTROLLED STUDY; FEMALE; FETUS; HISTOLOGY; KIDNEY INJURY; KIDNEY PARENCHYMA; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; TOXICOKINETICS;

ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; FEMALE; FETUS; FUNGICIDES, INDUSTRIAL; KIDNEY; MALE; MANEB; MANGANESE; MATERNAL-FETAL EXCHANGE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; ZINC; ZINEB;

RATTUS NORVEGICUS;

EID: 0032440146     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00128-3     Document Type: Article

References (36)

1. Beck S.L. Additional endpoints and overview of a mouse skeletal variant assay for detecting exposure to teratogenesis. Teratology. 47:1993;147-157.
2. Bertholf, R.L., 1988. Zinc. In: Seiler, H.G., Sigel, H. (Eds.), Handbook on Toxicity of Inorganic Compounds. Marcel Dekker, New York and Basel, pp. 787-800.
3. Branch S., Rogers J.M., Brownie C.F., Chernoff N. Supernumerary lumbar rib: manifestation of basic alteration in embryonic development of ribs. J. Appl. Toxicol. 16:1996;115-119.
4. Cummings A.M., Harris S.T., Rehnberg G.L. Effects of methyl benzimidazolecarbamate during early pregnancy in the rat. Fundam. Appl. Toxicol. 15:1990;528-535.
5. Eroschenko V.P., Abuel-Atta A.A., Grober M.S. Neonatal exposures to technical methoxychlor alters ovaries in adult mice. Reprod. Toxicol. 9:1995;379-387.
6. Garry V.F., Schreinemachers D., Harkins M.E., Griffith J. Pesticide appliers, biocides, and birth defects in rural Minnesota. Environ. Health Perspect. 104:1996;394-399.
7. Goyer, R.A., 1986. Toxic effects of metals. In: Amdur, M.O., Doull, J., Klaassen C.D. (Eds.), Casarett and Doull's Toxicology, The Basic Science of Poisons. Pergamon Press, pp. 623-680.
8. Guven K., Duce J.A., Pomerai D.I. Evaluation of a stress-inducible transgenic nematode strain for rapid aquatic toxicity testing. Aquat. Toxic. 29:1994;119-137.
9. Hasegawa R., Cabral R., Hoshiya T. et al. Carcinogenic potential of some pesticides in a medium-term multi-organ bioassay in rats. Int. J. Cancer. 54:1993;489-493.
10. Hassal, K.A., 1990. In: The Biochemistry and Uses of Pesticides, Structure, Metabolism, Mode of Action and Uses in Crop Protection. VCH, Weinheim and New York, pp. 263-361.
11. Jeffay S.C., Libbus B.L., Barbee R.R., Perreault S.D. Acute exposure of female hamsters to carbendazim (MBC) during meiosis results in aneuploid oocytes with subsequent arrest of embryonic cleavage and implantation. Reprod. Toxicol. 10:1996;183-189.
12. Johnson D.C., Sen M., Ogo H., Dey S.K. Initiation of embryo implantation and maintenance of early pregnancy in the rat by chlordecone (Kepone). Proc. Soc. Exp. Biol. Med. 195:1990;44-50.
13. Kackar R., Srivastava M.K., Raizada R.B. Induction of gonadal toxicity to male rats after chronic exposure to mancozeb. Ind. Health. 35:1997;104-111.
14. Kagi J.H.R., Schaffer A. Biochemistry of metallothionein. Biochem. perspect. biochem. 27:1988;8508-8515.
15. Kendrick, M.J., May, M.T., Plishka, M.J., Robinson, K.D., 1992. In: Metals in Biological Systems. Ellis Horwood, New York and London, pp. 179.
16. Larsson K.S., Arnander C., Cekanova E., Kjellberg M. Studies of teratogenic effects of the dithiocarbamates maneb, mancozeb and propineb. Teratology. 14:1976;171-184.
17. Lewin A.A., Miller R.K. Fetal toxicity of cadmium in the rat: decreased utero-placental blood flow. Toxicol. Appl. Pharm. 58:1981;297-306.
18. Lukens, R.J., 1971. In: Chemistry of Fungicidal Action. Springer-Verlag, New York and Berlin, pp. 125.
19. Marchal-Segault D., Lauge G. Ovarian activity of Drosophila melanogaster Meigen (Diptera), during a chronic intoxication with four fungicides:anatomical and cytological study. J. Environ. Sci. Health B. 32:1997;411-428.
20. Meco G., Bonifati V., Vanacore N., Fabrizio E. Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). Scand. J. Work. Environ. Health. 20:1994;301-305.
21. Noda T., Morita S., Yamano T., Shimizu M., Yamada A. Effects of triphenyltin acetate on pregnancy in rats by oral administration. Toxicol. Lett. 56:1991;207-212.
22. Perreault S.D., Jeffay S., Poss P., Laskey J.W. Use of the fungicide carbendazim as a model compound to determine the impact of acute chemical exposure during oocyte maturation and fertilization on pregnancy outcome in the hamster. Toxicol. Appl. Pharmacol. 114:1992;225-231.
23. Prasadad A.S. Clinical, biochemical and pharmacological role of zinc. Ann. Rev. Pharmacol. Toxicol. 20:1979;393-426.
24. Price C.J., Marr M.C., Myers C.B., Seely J.C., Heindel J.J., Schwetz B.A. The developmental toxicity of boric acid in rabbits. Fundam. Appl. Toxicol. 34:1996;176-187.
25. Soleo L., Defazio G., Scarcelli R., Zefferino R., Livrea P., Foa V. Toxicity of fungicides containing ethylene-bis-dithiocarbamate in serumless dissociated mesencephalic-striatal primary coculture. Arch. Toxicol. 70:1996;678-682.
26. Sowa B., Steibert E. Effect of oral cadmium administration to female rats during pregnancy on zinc, copper, and iron content in placenta, foetal liver, kidney, intestine, and brain. Arch. Toxicol. 56:1985;256-262.
27. Srivastava M.K., Raizada R.B. Developmental effect of technical dimethoate in rats, maternal and fetal toxicity evaluation. Indian J. Exp. Biol. 34:1996;329-333.
28. Subramoniam A., Agrawal D., Srivastava S.P., Seth P.K. Influence of mancozeb on mitogenically responsive lipids in rat cerebrum and liver. Indian J. Exp. Biol. 29:1991;943-945.
29. Tanaka T., Fujitani T., Takahashi O., Oishi S., Yoneyama M. Developmental toxicity study of piperonyl butoxide in CD rats. Toxicol. Ind. Health. 11:1995;175-184.
30. Tas S., Lauwerys R., Lison D. Occupational hazards for the male reproductive system. Crit. Rev. Toxicol. 26:1996;261-307.
31. Teramoto S., Kaneda M., Shirasu Y. Teratogenicity of ethylenethiourea in rats: relationship of dosage and time of administration to types of malformation. Teratology. 13:1975;215-216.
32. Trivedi N., Kakkar R., Srivastava M.K., Mithal A., Raizada R.B. Effect of oral administration of fungicide-mancozeb on thyroid gland of rat. Indian J. Exp. Biol. 31:1993;564-566.
33. Vachkova-Petrova R., Vassileva L., Antov G. et al. J. Toxicol. Clin. Exp. 11:1991;407-416.
34. Ware, G.W., 1983. In: Pesticides: Theory and Application. W.H. Freeman, pp. 293.
35. Wlostowski T. On metallothionein, cadmium, copper and zinc relationships in the liver and kidney of adult rats. Comp. Biochem. Physiol. 103C:1992;35-41.
36. Worthing, C.R., 1983. In: The Pesticide Manual. British Crop Protection Council, pp. 10180.