Enhanced activity of sodium-lithium countertransport in patients with cardiac syndrome X: A potential link between cardiac and metabolic syndrome X

Journal of the American College of Cardiology

Volumn 32, Issue 7, 1998, Pages 2031-2034

  Gaspardone, Achille ^a   Ferri, Claudio ^b   Crea, Filippo ^a   Versaci, Francesco ^a   Tomai, Fabrizio ^a   Santucci, Anna ^c   Chiariello, Luigi ^a   Gioffre, Pier A ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LITHIUM; SODIUM;

ADULT; ARTICLE; CLINICAL ARTICLE; DISEASE ASSOCIATION; FEMALE; GLUCOSE INTOLERANCE; HUMAN; HYPERINSULINEMIA; HYPERTENSION; MALE; PATHOGENESIS; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SMOOTH MUSCLE FIBER; SYNDROME X; VASOCONSTRICTION;

BIOLOGICAL TRANSPORT, ACTIVE; ERYTHROCYTES; FEMALE; HUMANS; INSULIN; ION TRANSPORT; LITHIUM; MALE; MICROVASCULAR ANGINA; MIDDLE AGED; RADIOIMMUNOASSAY; SODIUM;

EID: 0032439374     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(98)00470-7     Document Type: Article

References (27)

1. Cannon R.O., Epstein S.E. "Microvascular angina" as a cause of chest pain with angiographically normal coronary arteries. Am J Cardiol. 61:1988;1338-1343.
2. Maseri A., Crea F., Kaski J.C., Crake T. Mechanisms of angina pectoris in syndrome X. J Am Coll Cardiol. 17:1991;499-506.
3. Dean J.D., Jones C.J.H., Hutchison S.J., Peters J.R., Henderson A.H. Hyperinsulinaemia and microvascular angina ("syndrome X"). Lancet. 337:1991;456-457.
4. Botker H.E., Moller N., Ovesen P., et al. Insulin resistance in microvascular angina (syndrome X). Lancet. 342:1993;136-140.
5. Canessa M. Erythrocyte sodium-lithium countertransport another link between essential hypertension and diabetes . Curr Opin Nephrol Hypertens. 3:1994;511-517.
6. Kahn A.M., Allen J.C., Cragoe E.G. Jr, Shelat H. Sodium-lithium exchange and sodium-proton exchange are mediated by the same transport system in sarcolemmal vescicles from bovine superior mesenteric artery. Circ Res. 65:1989;818-828.
7. Rosskopf D., Dusing R., Siffert W. Membrane sodium-proton exchange and primary hypertension. Hypertension. 21:1993;607-617.
8. Richards T.N., Poston L., Goldsmith D.J.A., Cragoe E.J., Hilton P.J. Endothelin-induced contraction of human peripheral resistence vessels is partly dependent on stimulation of sodium-hydrogen exchange. J Hypertens. 7:1989;471-475.
9. + eritrocitario. [abstract] Cardiologia. 41:(Suppl 5):1996;7.
10. + countertransport. [abstract] J Am Coll Cardiol. 29:1997;157A.
11. Koren W., Koldanov R., Peleg E., Rabinowitz B., Rosenthal T. Enhanced red cell sodium-hydrogen exchange in microvascular angina. Eur Heart J. 18:1997;1296-1299.
12. Canessa M., Adaaguar N., Solomon H.S., Connolly, Tosteson DC. Increased sodium-lithium countertransport in red cells of patients with essential hypertension. N Engl J Med. 302:1980;772-776.
13. Hardman T.C., Lant A.F. Controversies surrounding erythrocyte sodium-lithium countertransport. J Hypertens. 14:1996;695-703.
14. Cannon R.O., Watson R.M., Rosing D.R., Epstein S.E. Angina caused by reduced vasodilator reserve of the small coronary arteries. J Am Coll Cardiol. 1:1983;1359-1373.
15. Tousulis D., Crake T., Lefroy D.C., Galassi A.R., Maseri A. Left ventricular hypercontractility and ST segment depression in patients with syndrome X. J Am Coll Cardiol. 22:1993;1607-1613.
16. Cannon R.O., Cattau E.L., Yakshe P.N., et al. Coronary flow reserve, esophageal motility, and chest pain in patients with angiographically normal coronary arteries. Am J Med. 88:1990;217-222.
17. Cannon R.O., Peden D.B., Berkebile C., Schenke W.H., Kaliner M.A., Epstein S.E. Airway hyperrsponsiveness in patients with microvascular angina evidence for a diffuse disorder of airway responsiveness . Circulation. 82:1990;2011-2017.
18. Sax F.L., Cannon R.O., Hanson C., Epstein S.E. Impaired forearm vasodilator reserve in patients with microvascular angina evidence of a generalized disorder of vascular function? N Engl J Med. 317:1987;1366-1370.
19. + antiport in the development of hypertension and insulin resistance. J Am Soc Nephrol. 3:1992;1049-1063.
20. Egashira K., Inou T., Hirooka Y., Yamada A., Urabe Y., Takeshita A. Evidence of impaired endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary angiograms. N Engl J Med. 328:1993;1659-1664.
21. Montorsi P., Fabbiocchi F., Loaldi A., et al. Coronary adrenergic hyperreactivity in patients with syndrome X and abnormal electrocardiogram at rest. Am J Cardiol. 68:1991;1698-1703.
22. Camici P.G., Marraccini P., Gistri R., Salvadori P.A., Sorace O., L'Abbate A. Adrenergically mediated coronary vasoconstriction in patients with syndrome X. Cardiovasc Drugs Ther. 8:1994;221-226.
23. Ungerer M., Chlistalla A., Karoglan M., Richardt G. Regulation of cardiac uptake 1 by intra- and extraneural norepinephrine, and by transmembranous sodium gradient. [abstract] Circulation. 94:1996;I-128.
24. 123I]metaiodobenzylguanidine myocardial scintigraphy. Circulation. 96:1997;821-826.
25. Anderson E.A., Hoffman R.P., Balon T.W., Sinkey C.A., Mark A.L. Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest. 87:1991;2246-2252.
26. Galassi A.R., Crea F., Araujo L.I., et al. Comparison of regional myocardial blood flow in syndrome X and one-vessel coronary artery disease. Am J Cardiol. 72:1993;134-139.
27. Meeder J.G., Blanksma P.K., Crijns H.J., et al. Mechanisms of angina pectoris in syndrome X assessed by myocardial perfusion dynamics and heart rate variability. Eur Heart J. 16:1995;1571-1577.