Aggressive and social behavior after alprazolam withdrawal: Experimental therapy with Ro 19-8022

Neuroscience and Biobehavioral Reviews

Volumn 23, Issue 2, 1998, Pages 155-161

  Krsiak M ^a   Podhorná, Jana ^a   Miczek, K A ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b TUFTS UNIVERSITY   (United States)

Author keywords

Aggression; Alprazolam; Mice; Ro 19 8022; Social behavior; Withdrawal

Indexed keywords

ALPRAZOLAM; BENZODIAZEPINE RECEPTOR STIMULATING AGENT; RO 19 8022; UNCLASSIFIED DRUG;

AGGRESSION; ANIMAL EXPERIMENT; ANXIETY; ATAXIA; BEHAVIOR DISORDER; CONFERENCE PAPER; CONTROLLED STUDY; DEFENSIVE BEHAVIOR; DRUG WITHDRAWAL; LOCOMOTION; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SEDATION; SOCIAL BEHAVIOR; WITHDRAWAL SYNDROME;

EID: 0032438410     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(98)00017-7     Document Type: Conference Paper

References (37)

1. File S.E. The history of benzodiazepine dependence: a review of animal studies. Neurosci. Biobehav. Rev. 14:1990;135-146.
2. File SE. The biology of benzodiazepine dependence. In: Hallström C, editor. Benzodiazepine dependence. New York: Oxford University Press, 1993. pp. 95-118.
3. Lader M. Historical development of the concept of tranquillizer dependence. In: Hallström C, editor. Benzodiazepine dependence. New York: Oxford University Press, 1993. pp. 46-57.
4. Woods J.H., Katz J.L., Winger G. Abuse liability of benzodiazepines. Pharmacol. Rev. 39:1992;251-413.
5. Woods JH, Katz JL, Winger G. Abuse and therapeutic use of benzodiazepine-like drugs. In: Bloom FE, Kupfer DJ, editors. Psychopharmacology: the fourth generation of progress. New York: Raven Press, 1995. pp. 1777-1791.
6. Miczek KA. The psychopharmacology of aggression. In: Iversen LL, Iversen SD, Snyder SH, editors. Handbook of psychopharmacology, vol. 19. New York: Plenum Publishing Corporation, 1987. pp. 183-328.
7. Miczek K.A., Kršiak M. Drug effects on agonistic behavior. Adv. Behavior. Pharmacol. 2:1979;87-162.
8. Miczek K.A., Weerts E.M., Haney M., Tidey J. Neurobiological mechanisms controlling aggression: preclinical developments for pharmacotherapeutic interventions. Neurosci. Biobehav. Rev. 18(1):1994;97-110.
9. Rodgers R.J., Waters A.J. Benzodiazepines and their antagonists: a pharmacoethological analysis with particular reference to effects on 'aggression'. Neurosci. Biobehav. Rev. 9:1985;21-35.
10. Randall L.O., Schallek W., Heise G.A., Keith E.F., Bagdon R.E. The psychosedative properties of methaminodiazepoxide. J. Pharmac. Exp. Ther. 129:1960;163-171.
11. Kršiak M. Timid singly-housed mice: their value in prediction of psychotropic activity of drugs. Br. J. Pharmacol. 55:1975;141-150.
12. Kršiak M, Šulcová A, Donát P, Tomašíková N, Kosar E, Mašek K. Can social and agonistic interactions be used to detect anxiolytic activity of drugs? In: Miczek KA, Kruk MR, Olivier B, editors. Ethopharmacological aggression research. New York: Liss; 1984. pp. 93-114.
13. Miczek K.A. Intraspecies aggression in rats: effects of d-amphetamine and chlordiazepoxide. Psychopharmacologia. 39:1974;275-301.
14. Miczek K.A., O'Donnell J.M. Alcohol and chlordiazepoxide increase suppressed aggression in mice. Psychopharmacology. 69:1980;39-44.
15. A and 5-HT anxiolytics. Psychopharmacology. 121:1995;38-56.
16. Mos J, Olivier B. Pro-aggressive actions of benzodiazepines. In: Olivier B, Mos J, Brain PF, editors. Ethopharmacology of agonistic behaviour in animals and humans. Dordrecht: Martinus Nijhoff Publishers, 1987. pp. 187-206.
17. Kršiak M. Effects of drugs on behaviour of aggressive mice. Br. J. Pharmacol. 65:1979;525-533.
18. Kršiak M., Šulcová A. Differential effects of six structurally related benzodiazepines on some ethological measures of timidity, aggression and locomotion in mice. Psychopharmacol. 101:1990;396-402.
19. Jenck F., Moreau J.-L., Bonetti E.P., Martin J.R., Haefely W.E. Ro 19-8022, a nonbenzodiazepine partial agonist at benzodiazepine receptors: neuropharmacological profile of a potential anxiolytic. J. Pharmacol. Exp. Ther. 262:1992;1121-1127.
20. Podhorná J., Kršiak M. A comparison of behavioural effects of Ro 19-8022 and nitrazepam in mice. Behav. Pharmacol. 7(Suppl. 1):1996;89-90.
21. Donát P. Measuring behaviour: the tools and the strategies. Neurosci. Biobehav. Rev. 15(4):1991;447-454.
22. Grant E.C., Mackintosh J.H. A comparison of the social postures of some common laboratory rodents. Behaviour. 21:1963;246-259.
23. Grant S.J., Galloway M.P., Mayor R., Fenerty J.P., Finkelstein M.F., Roth R.H., Redmond D.E. Jr. Precipitated diazepam withdrawal elevates noradrenergic metabolism in primate brain. Eur. J. Pharmacol. 107:1985;127-132.
24. File S.E., Wilks L.J. Changes in seizure threshold and aggression during chronic treatment with three anticonvulsants and on drug withdrawal. Psychopharmacol. 100:1990;237-242.
25. Gupta M.B., Nath C., Patnaik G.K., Saxena R.C. Effect of calcium channel blockers on withdrawal syndrome of lorazepam in rats. Indian J. Med. Res. 103:1996;310-314.
26. Herman Z.S., Drybanski A., Trzeciak H.I. Increased aggression in rats after withdrawal of long term used oxazepam. Experientia. 32(10):1976;1305-1306.
27. Podhorná J., Kršiak M. Increased aggression and timidity produced by withdrawal from diazepam. Homeostasis. 36(Suppl. 1):1995;116.
28. Šulcová A., Kršiak M., Donát P. b-CCE and FG 7142 increase defensiveness during intraspecies encounters in mice. Psychopharmacology. 108:1992;205-209.
29. Baldwin H.A., Aranko K., File S.E. Evidence that the incidence of withdrawal responses to benzodiazepines is linked to the development. Soc. Neurosci. Abstr. 13:1987;452.
30. Baldwin H.A., Hitchcott P.K., File S.E. Evidence that the increased anxiety detected in the elevated plus-maze during chlordiazepoxide withdrawal is not due to enhanced noradrenergic activity. Pharmacol. Biochem. Behavior. 34:1989;931-933.
31. File S.E. Chronic diazepam treatment: effect of dose on development of tolerance and incidence of withdrawal in an animal test of anxiety. Hum. Psychopharmacol. 3:1989;59-64.
32. File S.E., Baldwin H.A., Aranko K. Anxiogenic effects from benzodiazepine withdrawal are linked to the development of tolerance. Brain Res. Bull. 19:1987;607-610.
33. File S.E., Baldwin H.A., Hitchcott P.K. The effect of flumazenil on levels of anxiety in rats after one week of chronic diazepam treatment. Neurosci. Lett. S36:1989;S63.
34. Miller L.G., Greenblatt D.J., Chesley S., Schatzki A., Shader R.I. Chronic benzodiazepine adminitration. V. Rapid onset of behavioral and neurochemical alterations after discontinuation of alprazolam. Neuropharmacology. 29(3):1990;237-241.
35. Miczek K.A., Vivian J.A. Automatic quantification of withdrawal from 5-day diazepam in rats: ultrasonic distress vocalizations and hyperrflexia to acoustic startle stimuli. Psychopharmacology. 110:1993;379-382.
36. Vivian J.A., Farrell W.J., Sapperstein S.B., Miczek K.A. Diazepam withdrawal: effects of diazepam and gepirone on acoustic startle-induced 22 kHz ultrasonic vocalization. Psychopharmacology. 114:1994;101-108.
37. Pinna G., Galici R., Shneider H., Stephens D.N., Turski L. Electrophysiological and behavioural evidence that abecarnil suppresses dependence symptoms after alprazolam withdrawal in mice. Behav. Pharmacol. 6(Suppl. 1):1995;88-89.