Rhabdomyosarcoma-specific expression of the herpes simplex virus thymidine kinase gene confers sensitivity to ganciclovir

Journal of Pharmacology and Experimental Therapeutics

Volumn 286, Issue 2, 1998, Pages 1066-1073

  Morton, Christopher L ^a   Potter, Philip M ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CHLORAMPHENICOL ACETYLTRANSFERASE; GANCICLOVIR; MYOD PROTEIN; MYOGENIN; THYMIDINE KINASE; VIRUS ENZYME;

ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG SENSITIVITY; ENHANCER REGION; EXPRESSION VECTOR; GENE EXPRESSION; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; RHABDOMYOSARCOMA; TUMOR CELL DESTRUCTION; TUMOR CELL LINE; VIRUS GENE;

ANTIVIRAL AGENTS; BLOTTING, WESTERN; CLONE CELLS; GALACTOSIDASES; GANCICLOVIR; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MUSCLE NEOPLASMS; MYOD PROTEIN; PLASMIDS; POLYMERASE CHAIN REACTION; RHABDOMYOSARCOMA; SIMPLEXVIRUS; THYMIDINE KINASE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032437437     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Braun TK, Bober E, Buschhausen-Denker G, Kohtz S, Grzeschik KH and Arnold H-H (1989a) Differential expression of myogenic determination genes in muscle cells: Possible activation by the myf gene products. EMBO J 8:3617-3625.
2. Braun TK, Bober E, Winter B, Rosenthal N and Arnold H-H (1990) Myf-6, a new member of the human gene family of myogenic determination factors: Evidence for a gene cluster on chromosome 12. EMBO J 9:821-831.
3. Braun TK, Buschhausen-Denker G, Bober E, Tannich E and Arnold H-H (1989b) A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts. EMBO J 8:701-709.
4. Bubenik J, Perlmann P, Helstein K and Hoberger P (1970) Cellular and humoral immune responses to human urinary bladder carcinomas. Int J Cancer 5:310-319.
5. Chen L, Chen D, Manome Y, Dong Y, Fine HA and Kufe DW (1995) Breast cancer selective gene expression and therapy mediated by recombinant adenovirus containing the DF3/MUC1 promoter. J Clin Invest 96:2775-2782.
6. Dias PE, Dilling MB and Houghton PJ (1994) The molecular basis of skeletal muscle differentiation. Semin Diagn Pathol 11:3-14.
7. Dias PE, Parham DM, Shapiro DN, Tapscott SJ and Houghton PJ (1992) Monoclonal antibodies to the myogenic regulatory protein myoD1: Epitope mapping and diagnostic utility. Cancer Res 52:6431-6439.
8. Dias P, Parham DM, Shapiro DN, Webber BL and Houghton PJ (1990) Myogenic regulatory protein (MyoD1) expression in childhood solid tumors: Diagnostic utility in rhabdomyosarcoma. Am J Pathol 137:1283-1291.
9. Douglass EC, Valentine M, Etcubanas E, Parham DM, Webber BL, Houghton PJ, Houghton JA and Green AA (1987) A specific chromosomal abnormality in rhabdomyosarcoma (RMS). Cytogenet Cell Genet 45:148-155.
10. Edmonson DG and Olson EN (1989) A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program. Genes Dev 3:628-640.
11. Eustic DC, Feldman PA, Colberg-Poley M, Buckney RM and Neubauer RH (1991) A sensitive method for the detection of β-galactosidase in transfected mammalian cells. Biotechniques 11:739-742.
12. Faerman A, Goldhamer DJ, Puzis R, Emerson CP Jr and Shani M (1995) The distal human myoD enhancer sequences direct unique muscle-specific patterns of lacZ expression during mouse development. Dev Biol 171:27-38.
13. Fogh J, Fogh JM and Orfeo T (1977) One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J Natl Cancer Inst 59:221-226.
14. Foley GE, Lazarus H, Farber S, Uzman BG, Boone BA and McCarthy RF (1965) Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia. Cancer 18:522-529.
15. Gey GO, Coffman WD and Kubicek MT (1952) Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium. Cancer Res 12:264-265.
16. Giard DJ, Aaronson SA, Todaro GJ, Arnstein P, Kersey JH, Dosik H and Parks WP (1973) In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst 51:1417-1423.
17. Goldhamer DJ, Brunk BP, Faerman A, King A, Shani M and Emerson CP Jr (1995) Embryonic activation of the myoD gene is regulated by a highly conserved distal control element. Development 121:637-649.
18. Hazleton BJ, Houghton JA, Parham DM, Douglass EC, Torrance PM, Holt H and Houghton PJ (1987) Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma. Cancer Res 47:4501-4507.
19. Horton J, Houghton PJ and Houghton JA (1987) Reciprocal cross-resistance in human rhabdomyosarcomas selected for in vivo primary resistance to vincristine and L-phenylalanine mustard. Cancer Res 47:6288-6293.
20. Hosoi H, Sugimoto T, Matsumura T and Sawada T (1994) Molecular biological aspects of rhabdomyosarcoma. Jpn J Pediatr Surg 26:23-32.
21. Houghton PJ, Shapiro DN and Houghton JA (1991) Rhabdomyosarcoma: From the laboratory to the clinic. Pediatric Clin North Am 38:349-364.
22. Lozzio CB and Lozzio BB (1975) Human chronic myelogenous leukemia cell line with positive Philadelphia chromosome. Blood 45:321-324.
23. Manome Y, Abe M, Hagen MF, Fine HA and Kufe DW (1994) Enhancer sequences of DF3 gene regulate expression of the herpes simplex virus thymidine kinase gene and confer sensitivity of human breast cancer cells to ganciclovir. Cancer Res 54:5408-5413.
24. McAllister RM, Melnyk J, Finkelstein JZ, Adams EC Jr and Gardner MB (1969) Cultivation in vitro of cells derived from a human rhabdomyosarcoma. Cancer 24:520-526.
25. McKnight SL (1982) The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene. Nucleic Acids Res 8:5949-5964.
26. Micard D, Sobrier ML, Couderc JL and Dastugue B (1985) Purification of RNA-free plasmid DNA using alkaline extraction followed by Ultrogel A-2 column chromatography. Anal Biochem 148:121-126.
27. Miner JH and Wold B (1990) Herculin, a fourth member of the MyoD family of myogenic regulatory genes. Proc Natl Acad Sci USA 87:1089-1093.
28. Minowada J, Onuma T and Moore GE (1972) Rosette-forming human lymphoblastoid cell lines. I. Establishment and evidence for origin of thymus-derived lymphocytes. J Natl Cancer Inst 49:891-895.
29. Neumann JR, Morency CA and Russian KO (1987) A novel rapid assay for chloramphenicol acetyltransferase gene expression. Biotechniques 5:444-447.
30. Nichols WW, Murphy DG, Cristofalo VJ, Toji LH, Greene AE and Dwight SA (1977) Characterization of a new human diploid cell strain, IMR-90. Science 196:60-63.
31. Potter PM (1996) Directional PCR cloning of multiple copies of repeat sequences. Biotechniques 21:198-200.
32. Rhodes SJ and Konieczny SF (1990) Identification of MRF4: A new member of the muscle regulatory factor gene pathway. Genes Dev 3:2050-2061.
33. Rudnicki MA, Schnegelsberg Pnj, Stead RH, Braun TK, Arnold H-H and Jaenisch R (1993) MyoD or myf-5 is required for the formation of skeletal muscle. Cell 75:1351-1359.
34. Soule HD, Vazguez J, Long A, Albert S and Brennan MA (1973) A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 51:1409-1416.
35. Wang M, Rosenfeld M, Ashford R, Briscoe P, Siegal P, Deshane J, Alvarez R, Garver R and Curiel D (1996) A molecular chemotherapy approach for carcinoma of the cervix based upon targeted expression of the herpes simplex-thymidine kinase gene. Proc Am Assoc Cancer Res 37:345.
36. Weintraub H (1993) The MyoD family and myogenesis: redundancy, networks and thresholds. Cell 75:1241-1244.
37. Weintraub H, Davis R, Tapscott S, Thayer M, Krause M, Benezra B, Blackwell TK, Turner D, Rupp R, Hollenberg S, Zhuang Y and Lasser A (1991) The myoD gene family: nodal point during specification of the muscle cell lineage. Science 251: 761-766.
38. Wright WE, Sassoon DA and Lin VK (1989) Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD. Cell 56:607-617.
39. Yaffe D and Saxel O (1997) Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature 270:725-727.