Evidence for loss of heterozygosity in human psoriatic lesions

British Journal of Dermatology

Volumn 139, Issue 6, 1998, Pages 974-977

  Zachos, G ^a,b   Koumantaki, E ^b   Vareltzidis, A ^c   Spandidos, D A ^a,b,d  

^a INSTITUTE OF BIOLOGY   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

ALLELE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMOSOME 3P; CHROMOSOME 7P; CHROMOSOME 7Q; CHROMOSOME 8P; CHROMOSOME DELETION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; KERATINOCYTE; MALE; PRIORITY JOURNAL; PSORIASIS;

ADULT; DNA; FEMALE; HUMANS; KERATINOCYTES; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; POLYMERASE CHAIN REACTION; PSORIASIS;

EID: 0032437403     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1998.02551.x     Document Type: Article

References (24)

1. Ortonne J-P. Aetiology and pathogenesis of psoriasis. Br J Dermatol 1996; 135 (Suppl. 49): 1-5.
2. Harvima RJ, Viinamaki H, Harvima IT et al. Association of psychic stress with clinical severity and symptoms of psoriatic patients. Acta Derm Venereol (Stockh) 1996; 76: 467-71.
3. Gold MH, Holy AK, Roenigk HH. Beta-blocking drugs and psoriasis. J Am Acad Dermatol 1988; 19: 837-41.
4. Coopman SA, Johnson TM, Platt R et al. Cutaneous disease and drug reactions in HIV infection. N Engl J Med 1993; 328: 1670-4.
5. Naldi L. Psoriasis. Dermatol Clin 1993; 13: 635-47.
6. Tomfohrde J, Silverman A, Barnes R et al. Gene to familial psoriasis susceptibility mapped to the distal end of human chromosome 17q. Science 1994; 264: 1141-5.
7. Nair RP, Guo SW, Jenisch S et al. Scanning chromosome 17 for psoriasis susceptibility: lack of evidence for a distal 17q locus. Hum Hered 1995; 45: 219-30.
8. Trembath RC, Clough RL, Rosbotham JL et al. Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet 1997; 6: 813-20.
9. Matthews D, Fry L, Powles A et al. Evidence that a locus for familial psoriasis maps to chromosome 4q. Nat Genet 1996; 14: 231-3.
10. Basset-Seguin N, Escot C, Moles JP et al. c-fos and c-jun protooncogene expression is decreased in psoriasis: an in situ quantitative analysis. J Invest Dermatol 1991; 97: 672-8.
11. Elder JT, Klein SB, Tavakkol A et al. Growth factor and protooncogene expression in psoriasis. J Invest Dermatol 1990; 95: 7-9S.
12. Takahashi H, Iizuka H, Katagiri M. No evidence for the mutation of ras gene in psoriatic epidermis. Arch Dermatol Res 1990; 282: 8-11.
13. Hardas BD, Xhao X, Zhang J et al. Assignment of psoriasin to human chromosomal hand 1q21: coordinate overexpression of clustered genes in psoriasis. J Invest Dermatol 1996; 106: 753-8.
14. Rivas MV, Jarvis ED, Morisaki S et al. Identification of aberrantly regulated genes in diseased skin using the cDNA differential display technique. J Invest Dermatol 1997; 108: 188-94.
15. Hatzistamou J, Kiaris H, Ergazaki M, Spandidos DA. Loss of heterozygosity and microsatellite instability in human atherosclerotic plaques. Biochim Biophys Res Commun 1996; 225: 186-90.
16. Spandidos DA, Sourvinos G, Kiaris H, Tsamparlakis J. Microsatellite instability and loss of heterozygosity in human pterygia. Br J Ophthalmol 1997; 81: 493-6.
17. Murray JC, Buettow KH, Weber JL et al. A comprehensive human linkage map with centimorgan density. Cooperative Human Linkage Center (CHLC). Science 1994; 265: 2049-54.
18. Lasco D, Cavenee W, Nordenskjold M. Loss of constitutional heterozygosity in human cancer. Annu Rev Genet 1991; 25: 281-314.
19. Wei MH, Latif F, Bader S et al. Construction of a 600-kilobase cosmid clone and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on chromosome 3p21.3: progress toward the isolation of a lung cancer TSG. Cancer Res 1996; 56: 1487-92.
20. Prowse AH, Webster AR, Richards FM et al. Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors. Am J Hum Genet 1997; 60: 765-71.
21. Thibodeau SN, French AJ, Roche PC et al. Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res 1996; 56: 4836-40.
22. Kerr J, Leary JA, Hurst T et al. Allelic loss on chromosome 7q in ovarian adenocarcinomas: two critical regions and a rearrangement of the PLANH1 locus. Oncogne 1996; 13: 1815-18.
23. Narayanan L, Fritzell JA, Baker SM et al. Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2. Proc Natl Acad Sci USA 1997; 94: 3122-7.
24. Macoska JA, Trybus TM, Benson PD et al. Evidence for three tumor suppressor gene loci on chromosome 8p in human prostate cancer. Cancer Res 1995; 55: 5390-5.