Changes in the classification of carcinogenic chemicals in the work area. (Section III of the German List of MAK and BAT values)

Journal of Cancer Research and Clinical Oncology

Volumn 124, Issue 12, 1998, Pages 661-669

  Neumann, H G ^a   Thielmann, H W ^b   Filser, J G ^c   Gelbke, H P ^d   Greim, H ^c   Kappus, H ^e   Norpoth, K H ^f   Reuter, U ^c   Vamvakas, S ^a   Wardenbach, P ^g   Wichmann, H E ^c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d BASF SE   (Germany)

^e HUMBOLDT UNIVERSITY   (Germany)

^f UNIVERSITY OF DUISBURG ESSEN   (Germany)

^g FEDERAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (Germany)

Author keywords

Cancer risk; Carcinogen classification; Chemical carcinogens; List of MAK and BAT values

Indexed keywords

CARCINOGEN;

ARTICLE; CANCER; CANCER RISK; CHEMICAL CARCINOGENESIS; HUMAN; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; WORKPLACE;

ANIMALS; CARCINOGENS; HUMANS; OCCUPATIONAL EXPOSURE; RISK ASSESSMENT;

EID: 0032437259     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320050229     Document Type: Article

References (38)

1. American Conference of Governmental Industrial Hygienists (ACGIH) (1997) Threshold limit values for chemical substances and physical agents. Biological exposure indices. ACGIH, Cincinnati, Ohio
2. Ashby J (1994) Current issues in mutagenesis and carcinogenesis, no. 45. The genotoxicity of 1,4-dioxane. Mutat Res 322:141-150
3. Bolt HM, Gelbke HP, Greim H, Kimmerle G, Laib RJ, Neumann H-G, Norpoth KH, Pott F, Steinhoff D, Wardenbach P (1988) Stoffe mit begründetem Verdacht auf krebserzeugendes Potential (Abschnitt III, Gruppe B der MAK-Werte-Liste): Probleme und Lösungsmöglichkeiten. Arbeitsmed Sozialmed Praeventivmed 23:139-144
4. Csanády GA, Mendrala AL, Nolan RJ, Filser JG (1994) A physiologic pharmacokinetic model for styrene and styrene-7,8-oxide in mouse, rat and man. Arch Toxicol 68:143-157
5. Csanády GA, Kessler W, Filser JG (1995) Carcinogenic risk estimates for inhaled styrene based on the body burden of its metabolite styrene-7,8-oxide. Naunyn-Schmiedeberg's Arch Pharmacol [Suppl] 351:122
6. Deutsche Forschungsgemeinschaft (DFG) (1997) List of MAK and BAT Values 1997. VCH, Weinheim
7. Deutsche Forschungsgemeinschaft (DFG) (1998) List of MAK and BAT Values 1998. VCH, Weinheim
8. European Union (EU) (1993) Annex VI: general classification and labelling requirements for dangerous substances and preparations. Commission directive 93/21/EEC of April 27, 1993. Official Journal of the European Communities no. L 110A 5/4/1993
9. Filser JG, Schwegler U, Csanády GA, Greim H, Kreuzer PE, Kessler W (1993a) Species-specific pharmacokinetics of styrene in rat and mouse. Arch Toxicol 67:517-530
10. Filser JG, Kessler W, Csanády GA (1993b) Different approaches to estimate the carcinogenic risk of styrene based on animal studies. SIRC Rev 3:54
11. Gehring PJ, Young JD (1978) Application of pharmacokinetic principles in practice. In: Plaa GL, Duncan WAM (eds) Proceedings of the 1st International Congress of Toxicology. Toronto 1977, Academic Press, New York, pp 128-133
12. Greim H (ed) (1993) Ethylen. Toxikologisch-arbeitsmedizinische Begründungen von MAK-Werten, 19. Lieferung, VCH, Weinheim
13. Greim H (ed) (1996) 1,4-Dioxan. Toxikologisch-arbeitsmedizinische Begründungen von MAK-Werten, 23. Lieferung, VCH, Weinheim
14. Henschler D (ed) (1987) Styrol. Toxikologisch-arbeitsmedizinische Begründungen von MAK-Werten, 13. Lieferung, VCH, Weinheim
15. Henschler D (ed) (1992) Benzol. Toxikologisch-arbeitsmedizinische Begründungen von MAK-Werten, 18. Lieferung, VCH, Weinheim
16. Henschler D, Lehnert G (eds) (1994) Biological exposure values for occupational toxicants and carcinogens. Critical data evaluation for BAT and EKA values, vol I. VCH, Weinheim
17. International Agency for Research on Cancer (IARC) (1994) Styrene. IARC Monogr Eval Carcinog Risks Hum 60
18. International Agency for Research on Cancer (IARC) (1997) Epstein-Barr virus and Kaposi's sarcoma herpesvirus/human herpesvirus 8. IARC Monogr Eval Carcinog Risks Hum 70
19. Kessler W, Jiang X, Filser JG (1992) Pharmacokinetics of styrene-7,8-oxide in the mouse and the rat. In: Kreuz R, Piekarski C (eds) 32nd Annual Meeting of the German Society of Occupational Medicine, Köln. Gentner, Stuttgart, pp 622-626
20. Kociba RJ, McCollister SB, Park C, Torkelsen TR, Gehring PJ (1974) 1,4-Dioxane. I. Results of a 2-year ingestion study in rats. Toxicol Appl Pharmacol 30:275-286
21. Kolstad HA, Juel K, Olsen J, Lynge E (1995) Exposure to styrene and chronic health effects: mortality and incidence of solid cancers in the Danish reinforced plastics industry. Occup Environ Med 52:320-327
22. Korn M, Gfrörer W, Filser JG, Kessler W (1994) Styrene-7,8-oxide in blood of workers exposed to styrene. Arch Toxicol 68:524-527
23. McFee AF, Abbott MG, Gulati DK, Shelby MD (1994) Results of mouse bone marrow micronucleus studies on 1,4-dioxane. Mutat Res 322:145-148
24. Mirkova ET (1994) Activity of the rodent carcinogen 1,4-dioxane in the mouse bone marrow micronucleus assay. Mutat Res 322:142-144
25. Mirkova E, Ashby J (1989) Activity of the rodent carcinogen 1,4-dioxane in the mouse bone marrow micronucleus assay. Mutat Res 216:277
26. Morgan DL, Mahler JF, Dill, JA, Price HC Jr, O'Connor RW, Adkins B Jr (1993a) Styrene inhalation toxicity studies in mice. III. Strain differences in susceptibility. Fundam Appl Toxicol 21:326-333
27. 1 mice. Fundam Appl Toxicol 21:317-325
28. 1 mice. Fundam Appl Toxicol 20:325-335
29. NCI (National Cancer Institute) (1978) Bioassay of 1,4-dioxane for possible carcinogenicity. National Cancer Institute, Bethesda, NIH 78-1330, NTIS PB-285-711
30. Neumann H-G, Thielmann HW, Filser JG, Gelbke H-P, Greim H, Kappus H, Norpoth KH, Reuter U, Vamvakas S, Wardenbach P, Wichmann H-E (1997) Proposed changes in the classification of carcinogenic chemicals in the work area. Regul Toxicol Pharmacol 26:288-295
31. Osterman-Golkar S, Christakopoulos A, Zorec V, Svensson K (1995) Dosimetry of styrene 7,8-oxide in styrene and styrene oxide-exposed mice and rats by quantification of haemoglobin adducts. Chem Biol Interact 95:79-87
32. Pauwels W, Vodicèka P, Severi M, Plná K, Veulemans H, Hemminki K (1996) Adduct formation on DNA and haemoglobin in mice intraperitoneally administered with styrene. Carcinogenesis 17:2673-2680
33. Stott WT, Quast JF, Watanabe PG (1981) Differentiation of the mechanism of oncogenicity of 1,4-dioxane and 1,3-hexachlorobutadiene in the rat. Toxicol Appl Pharmacol 60:287-300
34. Tinwell H, Ashby J (1994) Activity of 1,4-dioxane in mouse bone marrow micronucleus assay. Mutat Res 322:148-150
35. Torkelson TR, Leong BK, Kociba RJ, Richter WA, Gehring PJ (1974) 1,4-Dioxane. II. Results of a 2-year inhalation study in rats. Toxicol Appl Pharmacol 30:287-298
36. 3H-dioxane in the rat and apparent lack of microsome catalyzed covalent-binding in target tissue. Life Sci 21:1447-1456
37. Woo YT, Lai DY, Arcos JC, Argus MF (1985) Ethylene glycol, diethylene glycol, dioxanes, and related compounds. In: Chemical Induction of Cancer, Vol IIIB. Academic Press, San Diego, pp 285-286
38. Young JD, Braun WH, Gehring PJ (1978) The dose-dependent fate of 1,4-dioxane in rats. J Environ Pathol Toxicol 2:263 282