Combination therapy with nefazodone and lithium: Safety and tolerability in fourteen patients

International Journal of Psychiatry in Clinical Practice

Volumn 2, Issue 4, 1998, Pages 251-254

  Hawley, Christopher ^a   Sivakumaran, Thanusha ^b   Huber, Thomas J ^a   Ige, Abayomi Kolade ^a  

^a QUEEN ELIZABETH II HOSPITAL   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

Author keywords

Combination; Lithium; Nefazodone; Safety; Serotonin

Indexed keywords

LITHIUM CARBONATE; NEFAZODONE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DEPRESSION; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; FATIGUE; FEMALE; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; MALE; POLYDIPSIA; POLYURIA; PRIORITY JOURNAL; TREMOR; XEROSTOMIA;

EID: 0032437239     PISSN: 13651501     EISSN: None     Source Type: Journal    
DOI: 10.3109/13651509809115369     Document Type: Article

References (17)

1. Austin MPV, Souza FGM, Goodwill GM (1991) Lithium augmentation in antidepressant resistant patients. A quantitative analysis. Br J Psychiatry 159: 510-4.
2. Joffe RT, Singer W, Levitt AJ, MacDonald C (1993) A placebo-controlled comparison of lithium and triiodothyronine augmentation of tricyclic antidepressant in unipolar refractory depression. Arch Gen Psychiatry 50: 387-93.
3. Stein G, Bernadt M (1993) Lithium augmentation therapy in tricyclic-resistant depression. A controlled trial using lithium in low and normal doses. Br J Psychiatry 162: 634-40.
4. Katona CL, Abou-Saleh M, Harrison DA et al (1995) Placebo-controlled trial of lithium augmentation of fluoxetine and lofepramine. Br J Psychiatry 166: 80-86.
5. McCance-Katz E, Price LH, Charney DS, Heninger GR (1992) Serotonergic function during lithium augmentation of refractory depression. Psychopharmacology 108: 93-97.
6. Committee on Safety of Medicines (1989) Fluvoxamine and fluoxetine - interaction with monoamine oxidase inhibitors, lithium and tryptophan. Current Problems 26.
7. Sternbach H (1991) The serotonin syndrome. Am J Psychiatry 148:705-13.
8. Radomski JW, Dursun SM, Reveley MA (1995) Toxic Serotonin Syndrome (TSS): An update and revised diagnosis criteria: J Psychopharmacology 1 (suppl) A21 (84).
9. Bauer M (1995) The combined use of lithium and SSRIs. J Serotonin Res 2: 69-76.
10. Taylor DP, Eison MS, Riblet LA et al (1982) Selective 5HT receptor blockade: pharmacologic studies of BMY13754, a non tricyclic antidepressant candidate. Soc Neurosci Abstr 8: 465.
11. Sharpley AL, Walsh AES, Cowen PJ (1996) Effect of nefazodone and lithium on sleep architecture in healthy men. J Psychopharmacol 10 (suppl 1): 26-29.
12. Montgomery SA, Åsberg MA (1979) A New Depression Scale Designed to be Sensitive to Change. Br J Psychiatry 134: 382-9.
13. Guy W (1976) Early Clinical Drug Evaluation (ECDEU) Assessment Manual for Psychopharmacology National Institute of Mental Health, Rockville, MD.
14. Hawley CJ, Roberts AG, Walker MH (1994) Tolerability of combined treatment with lithium and paroxetine: 19 cases treated under open conditions. J Psychopharmacol 8: 266-7.
15. Hawley CJ, Roberts AG, Baldwin DS (1994) Tolerability of combined treatment with lithium and fluoxetine: 14 cases treated under open conditions. Int Clin Psychopharmacol 9: 31-33.
16. Dinan TG (1993) Lithium augmentation in sertraline-resistant depression: a preliminary dose-response study. Acta Psychiatr Scand 88: 300-1.
17. Hawley CJ, Ratnam S, Pattinson HA et al (1996) Safety and tolerability of combined treatment with moclobemide and SSRIs: a preliminary study of 19 patients. J Psychopharmacol 10: 241-5.