Hepatitis C virus and immunoglobulin gene rearrangements: An early step in lymphomagenesis?

Acta Haematologica

Volumn 100, Issue 3, 1998, Pages 117-122

  Santini, G F ^a   Crovatto, M ^a   Giannini, F ^a   Bortolin, M T ^a   Mazzaro, C ^a   Invernizzi, F ^b,c  

^a FATEBENEFRATELLI HOSPITAL   (Italy)

^b Ospedale San Paolo ^*  (Italy)

^c University Hospital San Paolo   (Italy)

Author keywords

Hepatitis C virus; Immunoglobulin gene rearrangements; Mixed cryoglobulinemia

Indexed keywords

CELL DNA; IMMUNOGLOBULIN M; RHEUMATOID FACTOR; RNA;

ARTICLE; B LYMPHOCYTE; CARCINOGENESIS; CLONE; CONTROLLED STUDY; CRYOGLOBULINEMIA; DNA DETERMINATION; GENE REARRANGEMENT; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; LYMPHOMA; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; PRIORITY JOURNAL; RNA ANALYSIS;

CRYOGLOBULINEMIA; DNA; GENE REARRANGEMENT, B-LYMPHOCYTE; HEPACIVIRUS; HEPATITIS C; HUMANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 0032437049     PISSN: 00015792     EISSN: None     Source Type: Journal    
DOI: 10.1159/000040885     Document Type: Article

References (30)

1. Fiorini G, Bernasconi P, Sinico RA, Chianese R, Pozzi F, D'Amico G: Increased frequency of antibodies to ubiquitous viruses in essential mixed cryoglobulinemia. Clin Exp Immunol 1986;64:65-70.
2. Hurwitz DA, Quismorio FP, Friou GJ: Cryoglobulinemia in patients with infectious endocarditis. Clin Exp Immunol 1975;19:131-135.
3. Bombardieri S, Teichner A, Vicari G: Cryoglobulinemia in echinococcosis. Proc Soc Exp Biol Med 1973;142:941-945.
4. Steere AC, Hardin A, Ruddy S, Mummaw G, Melewista S: Lyme arthriris: Correlations of serum and cryoglobulin IgM with activity, and serum IgG with remission. Arthritis Rheum 1979;22:471-475.
5. Monteverde A, Rivano MT, Allegra GC, Zingrossi B, Baglioni P, Gobbi M: Essential mixed cryoglobulinemia, type II: A manifestation of a low-grade malignant lymphoma? Acta Haematol 1988;79:20-25.
6. Invernizzi F, Galli M, Serino G, Monti G, Meroni PL, Granatieri C, Zanussi C: Secondary and essential cryoglobulinemias. Acta Haematol 1983;70:73-77.
7. Monteverde A, Sabattini E, Poggi S, Ballaré M, Bertoncelli MC, De Vivo A, Briscomatis A, Roncador G, Falini B, Pileri S: Bone marrow findings further support the hypothesis that essential mixed cryoglobulinemia type II is characterized by a monoclonal B-cell proliferation. Leuk Lymphoma 1995;20:119-124.
8. Pascual M, Perrin L, Giostra E, Shifferli JA: Hepatitis C virus in patients with cryoglobulinemia type II. J Infect Dis 1990;162:569-570.
9. Ferri C, La Civita L, Longombardo G, Greco F, Bombardieri S: Hepatitis C virus and mixed cryoglobulinemia. Eur J Clin Invest 1993;23: 399-405.
10. Ferri C, Monti M, La Civita L, Longombardo G, Greco F, Pasero G, Gentilini P, Bombardieri S, Zignego A: Infection of peripheral blood mononuclear blood cells by hepatitis C virus in mixed cryoglobulinemia. Blood 1993; 82:3701-3704.
11. Galli M, Zehender G, Monti G, Ballaré M, Saccardo F, Piconi S, De Maddalena C, Bertoncelli MC, Rinaldi G, Invernizzi F, Monteverde A: Hepatitis C virus RNA in the bone marrow of patients with mixed cryoglobulinemia and in the subjects with noncryoglobulinemic chronic hepatitis type C. J Infect Dis 1995;171:672-675.
12. Sansonno D, Iacobelli AR, Cornacchiulo V, Iodice G, Dammacco F: Detection of hepatitis C virus proteins by immunofluorescence and HCV RNA genomic sequences by non-isotopic in situ hybridization in bone marrow and peripheral blood mononuclear cells of chronically HCV-infected patients. Clin Exp Immunol 1996;103:414-421.
13. Gabrielli A, Manzin A, Candela M, Caniglia ML, Paolucci S, Danieli MG, Clementi M: Active hepatitis C virus infection in bone marrow and peripheral blood mononuclear cells from patients with mixed cryoglobulinemia. Clin Exp Immunol 1994;97:87-93.
14. Perl A, Gorevic PD, Ryan DH, Condemi JJ, Ruszkowski RJ, Abraham GN: Clonal B cell expansions in patients with essential mixed cryoglobulinemia. Clin Exp Immunol 1989;76: 54-60.
15. Meroni PL, Barcellini W, Sinico RA, Fornasieri A, Sguotti C, Invernizzi F, D'Amico G, Zanussi C: In vitro synthesis of IgM rheumatoid factor by lymphocytes from patients with essential mixed cryoglobulinemia. Clin Exp Immunol 1986;65:303-310.
16. Franzin F, Efremov DG, Pozzato G, Tulissi P, Batista F, Burrone OR: Clonal B-cell expansions in peripheral blood of HCV-infected patients. Br J Haematol 1995;90:548-552.
17. Invernizzi F, Pioltelli P, Cattaneo R, Borzini P, Monti G, Zanussi C: A long-term follow-up study in essential cryoglobulinemia. Acta Haematol 1979;61:93-99.
18. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
19. Zehender G, De Maddalena C, Monti G, Ballaré M, Saccardo F, Piconi S, Invernizzi F, Monteverde A, Galli M: HCV genotypes in bone marrow and peripheral blood mononuclear cells of patients with mixed cryoglobulinemia. Clin Exp Rheumatol 1995;13:587-590.
20. Wan JH, Trainor KJ, Brisco MJ, Morley AA: Monoclonality in B cell lymphoma detected in paraffin wax embedded sections using the polymerase chain reaction. J Clin Pathol 1990;43: 888-890.
21. Werner C, Joller-Jemelka HI, Fontana A: Hepatitis C virus and cryoglobulinemia. N Engl J Med 1993;328:1122-1123.
22. Galli M, Monti G, Monteverde A, Invernizzi F, Pietrogrande M: Hepatitis C virus and mixed cryoglobulinemia. Lancet 1992;339:989.
23. Cacoub P, Lunel F, Musset L, Opolon P, Piette JC: Hepatitis C virus and cryoglobulinemia. N Engl J Med 1993;328:1121-1122.
24. Tanaka K, Aiyama T, Imai J, Morishita Y, Fukatsu T, Kakumu S: Serum cryoglobulin and chronic hepatitis C virus disease among Japanese patients. Am J Gastroenterol 1995;90: 1847-1852.
25. Willems M, Sheng L, Roskams T, Ramdani B, Doutrelepont JM, Nevens F, Durez P, Treille S, Adler M, Desmet V, Fevery J, Yap SH: Hepatitis C virus and its genotypes in patients suffering from chronic hepatitis C with or without a cryoglobulinemia-related syndrome. J Med Virol 1994;44:266-271.
26. Sinico RA, Ribero ML, Fornasieri A, Renoldi P, Zhou J, Fasola M, Portera G, Arrigo G, Gibelli A, D'Amico G, Tagger A: Hepatitis C virus genotype in patients with essential mixed cryoglobulinemia. Q J Med 1995;88:805-810.
27. Crovatto M, Ceselli S, Mazzaro C, Modolo ML, Martelli P, Mazzi G, Pozzato G, Giannini F, Barbisin M, Chiarotto B, Santini GF: HCV genotypes and cryoglobulinemia. Clin Exp Rheumatol 1995;13:579-582.
28. Zignego AL, Ferri C, Giannini C, Monti M, La Civita L, Careccia G, Longombardo G, Lombardini F, Bombardieri S, Gentilini P: Hepatitis C virus genotypes in patients with type II mixed cryoglobulinemia. Ann Intern Med 1996;124:31-34.
29. Bonagura VR, Kunkel HG, Pernis B: Cellular localization of rheumatoid idiotypes. J Clin Invest 1982;69:1356-1363.
30. Sansonno D, De Vita S, Cornacchiulo V, Carbone A, Boiocchi M, Dammacco F: Detection and distribution of hepatitis C virus-related proteins in lymph nodes of patients with type II mixed cryoglobulinemia and neoplastic or non-neoplastic lymphoproliferation. Blood 1996; 88:4638-4645.