Regulation of the cross-bridge cycle: The effects of MgADP, LC17 isoforms and telokin

Acta Physiologica Scandinavica

Volumn 164, Issue 4, 1998, Pages 381-388

  Somlyo, A V ^a,b   Matthew, J D ^a   Wu, X ^a   Khromov, A S ^a   Somlyo, A P ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Caged compounds; Cross bridges; Myosin; Myosin light chains; Smooth muscle; Telokin

Indexed keywords

8 BROMO CYCLIC AMP; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE MAGNESIUM; CALCIUM ION; CYCLIC AMP; CYCLIC GMP; FORSKOLIN; MYOSIN; MYOSIN LIGHT CHAIN; NUCLEOTIDE; PHOSPHOTRANSFERASE; TELOKIN; UNCLASSIFIED DRUG;

BLADDER MUSCLE; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; DEPHOSPHORYLATION; ILEUM; MUSCLE FORCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RABBIT; SMOOTH MUSCLE; SMOOTH MUSCLE RELAXATION; VELOCITY;

EID: 0032436266     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-201X.1998.tb10695.x     Document Type: Conference Paper

References (63)

1. 2+ upon illumination. J Am Chem Soc 111, 7957-7968.
2. Arner, A. 1982. Mechanical characteristics of chemically skinned guinea-pig taenia coli. Pflug Arch 395, 277-284.
3. Arner, A. & Hellstrand, P. 1985. Effects of calcium and substrate on force-velocity relation and energy turnover in skinned smooth muscle of the guinea-pig. J Physiol 360, 347-365.
4. Butler, T.M. & Davies, R.E. 1980. High-energy phosphates in smooth muscle. In: D.F. Bohr, A.P. Somlyo, & H.V. Sparks (eds) The Handbook of Physiology. The Cardiovascular System: Vol. II. Vascular Smooth Muscle, pp. 237-252. American Physiological Society, Bethesda, MD.
5. Butler, T.M., Siegman, M.J. & Mooers, S.U. 1983. Chemical energy usage during shortening and work production in mammalian smooth muscle. Am J Physiol 244, C234-C242.
6. Clark, J.F. 1994. The creatine kinase system in smooth muscle. Mol Cell Biochem 133/134, 221-232.
7. Dillon, P., Aksey, M., Driska, S. & Murphy, R.A. 1981. Myosin phosphorylation and the crossbriclge cycle in arterial smooth muscle. Science 211, 495-497.
8. 2-terminal-inserted myosin II heavy chain is expressed in smooth muscle of small muscular arteries. Am Physiol 272, C1532-1542.
9. Driska, S.P., Stein, P.G. & Porter, R. 1989. Myosin dephosphorylation during rapid relaxation of hog carotid artery smooth muscle. Am J Physiol 256, C315-C321.
10. Edman, K.A.P. 1979. The velocity of unloaded shortening and its relation to sarcomere length and isometric force in verterbrate muscle fibres. J Physiol 291, 143-159.
11. Francis, S.H. & Corbin, J.D. 1994. Progress in understanding the mechanism and function of cyclic GMP-dependent protein kinase. Adv Pharmacol 26, 115-170.
12. Fuglsang, A., Khromov, A., Torok, K., Somlyo, A.V. & Somlyo, A.P. 1993. Flash photolysis studies of relaxtion and crossbridge detachment: higher sensitivity of tonic than phasic smooth muscle to MgADP. J Mus Res Cell Motil 14, 666-673.
13. Gallagher, P.J. & Herring, B.P. 1991. The carboxyl terminus of the smooth muscle myosin light chain kinase is expressed as an independent protein, telokin. J Biol Chem 266, 23945-23952.
14. Gallagher, P.J., Herring, B.P. & Stull, J.T. 1997. Myosin light chain kinases. J Mus Res Cell Motil 18, 1-16.
15. Hai, C. & Murphy, R.A. 1989. Cross-bridge dephosphorylation and relaxation of vascular smooth muscle. Am J Physiol 256, C282-C287.
16. Hartshorne, D.J. 1987. Biochemistry of the contractile process in smooth muscle. In: L.R. Johnson (ed.) Physiology of the Gastrointestinal Tract, 2nd edn, pp. 423-482. Raven Press, New York.
17. Hartshorne, D.J., Ito, M. & Erdödi, F. 1998. Myosin light chain phosphatase. J Mus Res Cell Motil 19, 325-341.
18. Hasegawa, Y. & Morita, F. 1992. Role of 17-kDa essential light chain isororms of aorta smooth muscle myosin. J Biochem 111, 804-809.
19. Hathaway, D.R., Konicki, M.V. & Coolican, S.A. 1985. Phosphorylation of myosin light chain kinase from vascular smooth muscle by cAMP and cGMP dependent protein kinases. J Mol Cell Cardiol 17, 841-850.
20. Herring, B.P. & Smith, A.F. 1996. Telokin expression is mediated by a smooth muscle cell-specific promoter. Am J Physiol 270, 1656-1665.
21. Herring, B.P. & Smith, A.F. 1997. Telokin expression in AlO smooth muscle cells requires serum response factor. Am J Physiol 272, C1394-C1404.
22. Horiuti, K., Somlyo, A.V., Goldman, Y.E. & Somlyo, A.P. 1989. Kinetics of contraction initiated by flash photolysis of caged adenosine triphosphate in tonic and phasic smooth muscles, J Gen Physiol 94, 769-781.
23. Huang, W., Wilson, G.J., Lam, H. & Hambly, B. 1997. Conformational changes in the alkali light chains of myosin induced by trifluoperazine and detected using electron paramagnetic resonance and circular dichroism spectroscopy. Biophys J 72, A182.
24. Ito, M., Dabrowska, M., Guerriero, V. & Hartshorne, D.J. 1989. Identification of turkey gizzard of an acidic protein related to the C-terminal portion of smooth muscle myosin light chain kinase. J Biol Chem 264, 13971-13974.
25. Jiang, H., Colbran, J.L., Francis, S.H. & Corbin, J.D. 1992. Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries. J Biol Chem 267, 1015-1019.
26. Kamm, K.E. & Stull, J.T. 1985. The function of myosin light chain kinase phosphorylation in smooth muscle. Ann Rev Pharmacol Toxicol 25, 593-620.
27. Katoh, T. & Morita, F. 1996. Roles of light chains in the activity and conformation of smooth muscle myosin. J Biol Chem 271, 9992-9996.
28. Kelley, C.A., Takahashi, M., Yu, J.H. & Adelstein, R.S. 1993. An insert of 7 amino acids confers functional differences between smooth muscle myosins from the intestines and vasculature. J Biol Chem 268, 12848-12854.
29. 2+-activated contractions in smooth muscle. In: A.P. Somlyo & N.L. Stephens (eds) Regulation and Contraction of Smooth Muscle, pp. 437-448. Alan R. Liss, Inc., New York.
30. Khromov, A.S., Somlyo, A.V. & Somlyo, A.P. 1998. MgADP promotes a catch-like state developed through force-calcium hysteresis in tonic smooth muscle. Biophys J (in press).
31. Khromov, A., Somlyo, A.V. & Somlyo, A.P. 1996. Nucleotide binding by actomyosm as a determinant of relaxation kinetics of rabbit phasic and tonic smooth muscle. J Physiol 492, 669-673.
32. Khromov, A.S., Somlyo, A.V., Trentham, D.R., Zimmermann, B. & Somlyo, A.P. 1995. The role of MgADP in force maintenance by dephosphorylated cross-bridges in smooth muscle: a flash photolysis study. Biophys J 69, 2611-2622.
33. Komalavilas, P. & Lincoln, T.M. 1996. Phosphorylation of the inositol 1,4,5-trisphosphate receptor: cyclic GMP-dependent protein kinase mediates cAMP and cGMP dependent phosphorylation in the intact rat aorta. J Biol Chem 271, 21933-21938.
34. Krisanda, J.M. & Paul, R.J. 1983. Phosphagen and metabolite content during contraction in porcine carotid artery. Am J Physiol 244, C385-C390.
35. de Lanerolle, P., Nishikawa, M., Yost, D.A. & Adelstein, R.S. 1984. Increased phosphorylation of myosin light chain kinase after an increase in cyclic AMP in intact smooth muscle. Science 223, 1415-1417.
36. 2+-desensitization in vascular smooth muscle by activating the myosin light chain phosphatase. J Biol Chem 272, 5063-5068.
37. Malmqvist, U. & Arner, A. 1991. Correlation between isoform composition of the 17 kDa myosin light chain and maximal shortening velocity in smooth muscle. Pflug Arch 418, 523-530.
38. Malmqvist, U., Trybus, K.M., Yagi, S., Carmichael, J. & Fay, F.S. 1997. Slow cycling of unphosphorylated myosin is inhibited by calponin, thus keeping smooth muscle relaxed. Proc Natl Acad Sci USA 94, 7655-7660.
39. Matthew, J.D., Khromov, A.S., Trybus, K.M., Somlyo, A.P. & Somlyo, A.V. 1998. Myosin essential light chain isoforms modulate the velocity of shortening propelled by non phosphorylated cross bridges, J Biol Chem (in press).
40. Mitsui, T., Kitazawa, T. & Ikebe, M 1994. Correlation between high temperature dependence of smooth muscle myosinlight chain phosphatase activity and muscle relaxation rate. J Biol Chem 269, 5842-5848.
41. 2+-dependent stress maintenance in skinned swine carotid media. Am J Physiol 251, C892-C903.
42. Nabeshima, Y., Nameshima, Y., Nonomura, Y. & Fujii-Kuriyama, Y. 1987. Nonmuscle and smooth muscle light chain mRNAs are generated from a single gene by tissue specific alternative RNA splicing. J Biol Chem 262, 10608-10612.
43. Nishimura, J. & van Breemen, C. 1989. Direct regulation of smooth muscle contractile elements by second messengers. Biochem Biophys Res Comm 163, 929-935.
44. ++ sensitivity of permeabilized rabbit mesenteric artery: possible involvement of a second Ca regulatory system in smooth muscle contraction. J Pharmacol Exp Ther 258, 397-402.
45. Nishiye, E., Somlyo, A.V., Torok, K. & Somlyo, A.P. 1993. The effects of MgADP on crossbridge kinetics: A laser flash photolysis study of guinea-pig smooth muscle. J Physiol 460, 247-271.
46. Pfitzer, G., Merkel, L., Rüegg, J.C. & Hofmann, F. 1986. Cyclic GMP-dependent protein kinase relaxes skinned fibers from guinea pig taenia coli. Pflug Arch 407, 87-91.
47. Rovner, A.S., Freyzon, Y. & Trybus, K.M. 1997. An insert in the motor domain determines the functional properties of expressed smooth muscle myosin isoforms.
48. Shirinsky, V.P., Vorotnikov, A.V., Birukov, K.G., Nanaev, A.K., Collinge, M., Lukas, T.J., Sellers, J.R. & Watterson, D.M. 1993. A kinase-relatecl protein stabilized unphosphorylated smooth muscle myosin minifilaments in the presence of ATP. J Biol Chem 268, 16578-16583.
49. Siegman, M.J., Butler, T.M., Mooers, S.U. & Davies, R.E. 1980. Chemical energetics of force development, force maintenance, and relaxation in mammalian smooth muscle. J Gen Physiol 76, 609-629.
50. Siemankowski, R.F., Wiseman, M.O. & White, H.D. 1985. ADP dissociation from actomyosin subfragment 1 is sufficiently slow to limit the unloaded shortening velocity in vertebrate muscle. Proc Natl Acad Sci USA 82, 658-662.
51. Silver, D.L., Vorotnikov, A.V., Watterson, D.M., Shirinsky, V.P. & Sellers, J.R. 1997. Sites of interaction between kinase-related protein and smooth muscle myosin. J Biol Chem 272, 25353-25359.
52. Sobieszek, A., Borkowski, J. & Babiychuk, V.S. 1997. Purification and characterization of a smooth muscle myosin light chain kinase-phosphatase complex. J Biol Chem 272, 7034-7041.
53. Somlyo, A.V., Goldman, Y.E., Fujimori, T., Bond, M., Trentham, D.R. & Somlyo, A.F. 1988. Crossbridge kinetics, cooperactivity and negatively strained crossbridges in vertebrate smooth muscle: A laser flash photolysis study. J Gen Physiol 91, 165-192.
54. 2+-sensitivity and of the time course of contraction in smooth muscle: a major role of protein phosphatases? Adv Prot Phosphatases 5, 181-195.
55. Somlyo, A.V. & Somlyo, A.P. 1967. Active state and catch-like state in rabbit main pulmonary artery. J Gen Physiol 50, 168-169.
56. Somlyo, A.P. & Somlyo, A.V. 1994. Signal transduction and regulation in smooth muscle. Nature 372, 231-236.
57. Stull, J.T., Gallagher, P.J., Herring, B.P. & Kamm, K.E. 1991. Vascular smooth muscle elements: cellular regulation. Hypertension 17, 723-732.
58. Trybus, K.M., Waller, G.S. & Chatman, T.A. 1994. Coupling of ATPase activity and motility in smooth muscle myosin is mediated by the regulatory light chain. J Cell Biol 124, 963-969.
59. Vyas, T.B., Mooers, S.U., Narayan, S.R., Witherell, J.C., Siegman, M.J. & Butler, T.M. 1992. Cooperative activation of myosin light chain phosphorylation in permeabilized smooth muscle. Am J Physiol 263, C210-C219.
60. White, S., Martin, A.E. & Periasamy, M. 1993. Identification of a novel smooth muscle myosin heavy chain of cDNA: isoform diversity in the S1 head region. Am J Physiol 264, C1252-C1258.
61. Wu, X., Haystead, T.A.J., Nakamoto, R.K., Somlyo, A.V. & Somlyo, A.P. 1998. Acceleration of regulatory myosin light chain dephosphorylation and relaxation of smooth muscle-by telokin and cyclic nucleotide-activated kinase. J Biol Chem 273, 11362-11369.
62. Wu, X., Somlyo, A.V. & Somlyo, A.P. 1996. Cyclic GMP-dependent stimulation reverses G-protein-coupled inhibition of smooth muscle myosin light chain phosphatase. Biochem Biophys Res Comm 220, 658-663.
63. Yang, Z. & Sweeney, H.L. 1995. Restoration of phosphorylation-dependent regulation to the skeletal muscle myosin regulatory light chain. J Biol Chem 270, 24646-24649.