Rhazinal, a formylrhazinilam derivative from a Malayan Kopsia

Natural Product Letters

Volumn 12, Issue 4, 1998, Pages 307-310

  Kam, Toh Seok ^a   Tee, Yee Ming ^a   Subramaniam, G ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Kopsia species; New indole alkaloid

Indexed keywords

INDOLE ALKALOID;

ARTICLE; CHEMICAL STRUCTURE; NONHUMAN; PHYTOCHEMISTRY; SPECTROSCOPY;

KOPSIA; KOPSIA TEOI;

EID: 0032436212     PISSN: 10575634     EISSN: None     Source Type: Journal    
DOI: 10.1080/10575639808048307     Document Type: Article

References (9)

1. T. S. Kam, K. Yoganathan, C. H. Chuah and Chen Wei (1993). Aspidofractinine alkaloids from a new Kopsia species. Phytochemistry, 32, 1343.
2. T. S. Kam, K. Yoganathan, C. H. Chuah (1993). Kopsidine A and kopsidine B, two novel indole alkaloids from a Malaysian Kopsia. Tetrahedron Lett., 34, 1819.
3. T. S. Kam, K. Yoganathan and Chen Wei (1996) Novel cage indoles from a Malaysian Kopsia. J. Nat. Prod., 59, 1109.
4. T. S. Kam and K. Yoganathan (1996). Three aspidofractinine-type alkaloids from Kopsia teoi. Phytochemistry, 42, 539.
5. T. S. Kam, K. Yoganathan, S. L. Mok (1997). Aspidofractinine alkaloids from Kopsia teoi. Phytochemistry, 46, 789.
6. T. Varea, C. Kan, F. Remy, T. Sevenet, J. C. Quirion, H. P. Husson and A. H. A. Hadi (1993). Indole alkaloids from Kopsia teoi. J. Nat. Prod., 56, 2166.
7. N. Aimi, N. Uchida, N. Ohya, H. Hosokawa, H. Takayama, S. Sakai, L. A. Mendonza, L. Polz and J. Stockigt (1991). Novel indole alkaloids from cell suspension cultures of Aspidosperma quebracho blanco Schlecht. Tetrahedron Lett., 32, 4949.
8. T. S. Kam, and G. Subramaniam (1998). Oxo-derivatives of kopsine- and rhazinilam-type alkaloids from a North Borneo Kopsia. Nat. Prod. Lett., 11, 131.
9. Semisynthetic formyl- and diformylrhazinilam derivatives have been very recently reported in connection with a study of the antitubulin activity of rhazinilam analogues, B. David, T. Sevenet, O. Thoison, K. Awang, M. Pais, M. Wright and D. Guenard (1997). Hemisynthesis of rhazinilam analogues: structure-activity relationships on tubulin-microtubule system. Bioorg. Med. Chem. Lett., 7, 2155.