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Volumn 82, Issue 3-4, 1998, Pages 278-283

The genomic breakpoint and chimeric transcripts in the EWSR1-ETV4/E1AF gene fusion in Ewing sarcoma

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC PROTEIN; DNA; DNA BINDING PROTEIN; MESSENGER RNA; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR;

EID: 0032435968     PISSN: 03010171     EISSN: None     Source Type: Journal    
DOI: 10.1159/000015119     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 0028209984 scopus 로고
    • DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma
    • Bailly R-A, Bosselut R, Zucman J, Cormier F, Delattre O, Roussel, M, Thomas G, Ghysdael J: DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma. Mol cell Biol 14:3230-3241 (1994).
    • (1994) Mol Cell Biol , vol.14 , pp. 3230-3241
    • Bailly, R.-A.1    Bosselut, R.2    Zucman, J.3    Cormier, F.4    Delattre, O.5    Roussel, M.6    Thomas, G.7    Ghysdael, J.8
  • 2
    • 0027385518 scopus 로고
    • Mapping and positioning DNA-binding proteins along genomic DNA. Structure of D. melanogaster ribosomal Alu-repeats and 1.688 satellite chromatin
    • Belikov SV, Belgovsky AI, Partolina MP, Kasrpov VL, Mirzabekov AD: Mapping and positioning DNA-binding proteins along genomic DNA. Structure of D. melanogaster ribosomal Alu-repeats and 1.688 satellite chromatin. Nucl Acids Res 21:4796-4802 (1993).
    • (1993) Nucl Acids Res , vol.21 , pp. 4796-4802
    • Belikov, S.V.1    Belgovsky, A.I.2    Partolina, M.P.3    Kasrpov, V.L.4    Mirzabekov, A.D.5
  • 3
    • 0029061936 scopus 로고
    • Molecular analysis of a t(11;22) translocation junction in a case of Ewing's sarcoma
    • Bhagirath T, Abe S, Nojima T, Yoshida MC: Molecular analysis of a t(11;22) translocation junction in a case of Ewing's sarcoma. Genes Chrom Cancer 13:126-132 (1995).
    • (1995) Genes Chrom Cancer , vol.13 , pp. 126-132
    • Bhagirath, T.1    Abe, S.2    Nojima, T.3    Yoshida, M.C.4
  • 5
  • 6
    • 0024504147 scopus 로고
    • Ph1 + bcr-acute leukemias: Implications of Alu sequences in a chromosomal translocation occurring in the new cluster region within the BCR gene
    • Chen SJ, Chen Z, D'Auriol L, Le Coniat M, Grausz D, Berger R: Ph1 + bcr-acute leukemias: Implications of Alu sequences in a chromosomal translocation occurring in the new cluster region within the BCR gene. Oncogene 4:195-202 (1989).
    • (1989) Oncogene , vol.4 , pp. 195-202
    • Chen, S.J.1    Chen, Z.2    D'Auriol, L.3    Le Coniat, M.4    Grausz, D.5    Berger, R.6
  • 7
    • 0024461175 scopus 로고
    • Structural alterations of the BCR and ABL genes in Ph 1 positive leukemias with rearrangements in the BCR first intron: Further evidence implicating Alu sequences in the chromosomal translocation
    • Chen SJ, Chen Z, Font M-P, D'Auriol L, Larsen C-J, Berger R: Structural alterations of the BCR and ABL genes in Ph 1 positive leukemias with rearrangements in the BCR first intron: Further evidence implicating Alu sequences in the chromosomal translocation. Nucl Acids Res 17:7631-7642 (1989).
    • (1989) Nucl Acids Res , vol.17 , pp. 7631-7642
    • Chen, S.J.1    Chen, Z.2    Font, M.-P.3    D'Auriol, L.4    Larsen, C.-J.5    Berger, R.6
  • 12
    • 0021811764 scopus 로고
    • Structural organization of the BCR gene and its role in the Ph′ translocation
    • Heisterkamp N, Stam K, Groffen J, de Klein A, Grosveld G: Structural organization of the BCR gene and its role in the Ph′ translocation. Nature 315:758-761 (1985).
    • (1985) Nature , vol.315 , pp. 758-761
    • Heisterkamp, N.1    Stam, K.2    Groffen, J.3    De Klein, A.4    Grosveld, G.5
  • 14
    • 0027251754 scopus 로고
    • Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: A new human member of the ets oncogene family
    • Higashino F, Yoshida K, Fujinaga Y, Kamio K, Fijinaga K: Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: A new human member of the ets oncogene family. Nucl Acids Res 21:547-553 (1993).
    • (1993) Nucl Acids Res , vol.21 , pp. 547-553
    • Higashino, F.1    Yoshida, K.2    Fujinaga, Y.3    Kamio, K.4    Fijinaga, K.5
  • 15
    • 0028908322 scopus 로고
    • Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters
    • Higashino F, Yoshida K, Noumi T, Seiki M, Fujinaga K: Ets-related protein E1A-F can activate three different matrix metalloproteinase gene promoters. Oncogene 10:1461-1463 (1995).
    • (1995) Oncogene , vol.10 , pp. 1461-1463
    • Higashino, F.1    Yoshida, K.2    Noumi, T.3    Seiki, M.4    Fujinaga, K.5
  • 16
    • 0029148895 scopus 로고
    • Assignment of ets-related transcription factor E1A-F (ETV4) to human chromosome region 17q21
    • Isobe M, Yamagishi F, Yoshida K, Higashino F, Fujinaga K: Assignment of ets-related transcription factor E1A-F (ETV4) to human chromosome region 17q21. Genomics 28:357-359 (1995).
    • (1995) Genomics , vol.28 , pp. 357-359
    • Isobe, M.1    Yamagishi, F.2    Yoshida, K.3    Higashino, F.4    Fujinaga, K.5
  • 19
    • 0030071143 scopus 로고    scopus 로고
    • A single ets-rdated transcription factor, E1AF, confers invasive phenotype on human cancer cells
    • Kaya M, Yoshida K, Higashino F, Mitaka T, Ishii S, Fujinaga K: A single ets-rdated transcription factor, E1AF, confers invasive phenotype on human cancer cells. Oncogene 12:221-227 (1996).
    • (1996) Oncogene , vol.12 , pp. 221-227
    • Kaya, M.1    Yoshida, K.2    Higashino, F.3    Mitaka, T.4    Ishii, S.5    Fujinaga, K.6
  • 20
    • 0029087408 scopus 로고
    • The emerging molecular genetics of sarcoma translocations
    • Ladanyi M: The emerging molecular genetics of sarcoma translocations. Diag Mol Path 4:162-173 (1995).
    • (1995) Diag Mol Path , vol.4 , pp. 162-173
    • Ladanyi, M.1
  • 21
    • 0027497958 scopus 로고
    • Duplication of small segments within the major breakpoint cluster region in chronic myelogenous leukemia
    • Litz CE, McClure JS, Copenhaver CM, Brunning RD: Duplication of small segments within the major breakpoint cluster region in chronic myelogenous leukemia. Blood 81:1567-1572 (1993).
    • (1993) Blood , vol.81 , pp. 1567-1572
    • Litz, C.E.1    McClure, J.S.2    Copenhaver, C.M.3    Brunning, R.D.4
  • 22
    • 0027230568 scopus 로고
    • Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation
    • USA
    • May WA, Gishizky ML, Lessnick SL, Lunsford LB, Lewis BC, Delattre O, Zucman J, Thomas G, Denny CT: Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proc natl Acad Sci, USA 90:5752-5756 (1993).
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 5752-5756
    • May, W.A.1    Gishizky, M.L.2    Lessnick, S.L.3    Lunsford, L.B.4    Lewis, B.C.5    Delattre, O.6    Zucman, J.7    Thomas, G.8    Denny, C.T.9
  • 24
    • 0028074607 scopus 로고
    • The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains
    • Ohno T, Ouchida M, Lee L, Gatalica Z, Rao VN, Reddy ESP: The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domains. Oncogene 9:3087-3097 (1995).
    • (1995) Oncogene , vol.9 , pp. 3087-3097
    • Ohno, T.1    Ouchida, M.2    Lee, L.3    Gatalica, Z.4    Rao, V.N.5    Reddy, E.S.P.6
  • 25
  • 27
    • 0027197554 scopus 로고
    • Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein
    • Rao VN, Ohno T, Prasad DD, Bhattacharya G, Reddy ES: Analysis of the DNA-binding and transcriptional activation functions of human Fli-1 protein. Oncogene 8:2167-2173 (1993).
    • (1993) Oncogene , vol.8 , pp. 2167-2173
    • Rao, V.N.1    Ohno, T.2    Prasad, D.D.3    Bhattacharya, G.4    Reddy, E.S.5
  • 28
    • 0026335817 scopus 로고
    • Erg, an ets-related gene, codes for sequence-specific transcriptional activators
    • Reddy ES, Rao VN: erg, an ets-related gene, codes for sequence-specific transcriptional activators. Oncogene 6:2285-2289 (1991).
    • (1991) Oncogene , vol.6 , pp. 2285-2289
    • Reddy, E.S.1    Rao, V.N.2
  • 29
    • 0023646823 scopus 로고
    • A sex chromosome rearrangement in human XX male caused by Alu-Alu recombination
    • Rouyer F, Simmler MC, Page DC, Weissenbach J: A sex chromosome rearrangement in human XX male caused by Alu-Alu recombination. Cell 51:417-425 (1987).
    • (1987) Cell , vol.51 , pp. 417-425
    • Rouyer, F.1    Simmler, M.C.2    Page, D.C.3    Weissenbach, J.4
  • 31
    • 0029927373 scopus 로고    scopus 로고
    • A novel chimera gene between EWS and E1AF, encoding the adenovirus E1A enhancer-binding protein, in extraosseous Ewing's sarcoma
    • Urano F, Umezawa A, Hong W, Kikuchi H, Hata J: A novel chimera gene between EWS and E1AF, encoding the adenovirus E1A enhancer-binding protein, in extraosseous Ewing's sarcoma. Biochem biophys Res Commun 219:608-612 (1996).
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 608-612
    • Urano, F.1    Umezawa, A.2    Hong, W.3    Kikuchi, H.4    Hata, J.5
  • 32
    • 0024497357 scopus 로고
    • Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukemia, with a breakpoint within the first intron of the BCR gene
    • van der Feltz MJM, Shivji MKK, Allen PB, Heisterkamp N, Groffen J Wiedemann LM: Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukemia, with a breakpoint within the first intron of the BCR gene. Nucl Acids Res 17:1-10 (1989).
    • (1989) Nucl Acids Res , vol.17 , pp. 1-10
    • Van Der Feltz, M.J.M.1    Shivji, M.K.K.2    Allen, P.B.3    Heisterkamp, N.4    Groffen, J.5    Wiedemann, L.M.6
  • 33
    • 0021957944 scopus 로고
    • Comparison of physical and genetic properties of palindromic DNA sequences
    • Warren GJ, Green RL: Comparison of physical and genetic properties of palindromic DNA sequences. J Bacteriol 161:1103-1111 (1985).
    • (1985) J Bacteriol , vol.161 , pp. 1103-1111
    • Warren, G.J.1    Green, R.L.2
  • 34
    • 0027458366 scopus 로고
    • The Ets family of transcription factors
    • Wasylyk B, Hahr SL, Giovane A: The Ets family of transcription factors. Eur J Biochem 211:7-18 (1993).
    • (1993) Eur J Biochem , vol.211 , pp. 7-18
    • Wasylyk, B.1    Hahr, S.L.2    Giovane, A.3
  • 36
    • 0026528326 scopus 로고
    • Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells
    • Xin J-H, Cowie A, Lachance P, Hassell JA: Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. Genes Dev 6:481-496 (1992).
    • (1992) Genes Dev , vol.6 , pp. 481-496
    • Xin, J.-H.1    Cowie, A.2    Lachance, P.3    Hassell, J.A.4
  • 37
    • 0024828177 scopus 로고
    • Binding sites of HeLa cell nuclear proteins on the upstream region of adenovirus type 5 E1A gene
    • Yoshida K, Narita M, Fujinaga K: Binding sites of HeLa cell nuclear proteins on the upstream region of adenovirus type 5 E1A gene. Nucl Acids Res 17:10015-10034 (1989).
    • (1989) Nucl Acids Res , vol.17 , pp. 10015-10034
    • Yoshida, K.1    Narita, M.2    Fujinaga, K.3
  • 40
    • 0031045193 scopus 로고    scopus 로고
    • Interethnic polymorphism of EWS intron 6: Genome plasticity mediated by Alu retroposition and recombination
    • Zucman-Rossi J, Batzer MA, Stoneking M, Delattre O, Thomas G: Interethnic polymorphism of EWS intron 6: genome plasticity mediated by Alu retroposition and recombination. Hum Genet 99:357-363 (1997).
    • (1997) Hum Genet , vol.99 , pp. 357-363
    • Zucman-Rossi, J.1    Batzer, M.A.2    Stoneking, M.3    Delattre, O.4    Thomas, G.5


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