The nature of gerontogenes and vitagenes. Antiaging effects of repeated heat shock on human fibroblasts

Annals of the New York Academy of Sciences

Volumn 854, Issue , 1998, Pages 54-60

  Rattan, Suresh I S ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CELL AGING; CONFERENCE PAPER; FIBROBLAST; GENE; GENETIC SCREENING; HEAT SHOCK; HUMAN; QUALITY OF LIFE;

EID: 0032434709     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb09891.x     Document Type: Conference Paper

References (37)

1. HOLLIDAY, R. 1995. Understanding Ageing. Cambridge University Press. Cambridge.
2. RATTAN, S.I.S. 1995. Ageing - a biological perspective. Mol. Aspects Med. 16: 439-508.
3. RATTAN, S.I.S. 1985. Beyond the present crisis in gerontology. BioEssays 2: 226-228.
4. RATTAN, S.I.S. 1995. Gerontogenes: Real or virtual? FASEB J. 9: 284-286.
5. ROSE, M.R. 1991. Evolutionary Biology of Aging. Oxford University Press. New York.
6. KIRKWOOD, T.B.L. 1992. Biological origins of ageing. In Oxford Textbook of Geriatric Medicine. J.G. Evans & T.F. Williams, Eds.: 35-40. Oxford University Press. Oxford.
7. CHARLESWORTH, B. & K.A. HUGHES. 1996. Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence. Proc. Natl. Acad. Sci. USA 93: 6140-6145.
8. MAYR, E. 1997. The object of selection. Proc. Natl. Acad. Sci. USA 94: 2091-2094.
9. FINCH, C.E. & M.C. PIKE. 1996. Maximum life span predictions from the Gompertz mortality model. J. Gerontol. Biol. Sci. 51A: B183-B194.
10. JOHNSON, T.E. 1997. Genetic influences on aging. Exp. Gerontol. 32: 11-22.
11. McGuE, M., J.W. VAUPEL, N. HOLM & B. HARVALD. 1993. Longevity is moderately heritable in a sample of Danish twins born 1870-1880. J. Gerontol. 48: B237-B244.
12. YASHIN, A.I. & I. IACHINE. 1995. How long can humans live? Lower bound for biological limit of human longevity calculated from Danish twin data using correlated frailty model. Mech. Ageing Dev. 80: 147-169.
13. MARTIN, G.M. 1985. Genetics and aging: The Werner syndrome as a segmented progeroid syndrome. Adv. Exp. Med. Biol. 190: 161-170.
14. JAZWINSKI, S.M. 1996. Longevity, genes, and aging. Science 273: 54-59.
15. PIANTANELLI, L., A. BASSO & G. ROSSOLINI. 1994. Modelling the link between aging rate and mortality rate. Ann. N.Y. Acad. Sci. 719: 136-145.
16. YU, C.-E. et al. 1996. Positional cloning of the Werner's syndrome gene. Science 272: 258-262.
17. MASORO, E.J. 1995. Dietary restriction. Exp. Gerontol. 30: 291-298.
18. MASORO, F.J. & S.N. AUSTAD. 1996. The evolution of the antiaging action of dietary restriction: A hypothesis. J. Gerontol. Biol. Sci. 51A: B387-B391.
19. MCFARLAND, G.A. & R. HOLLIDAY. 1994. Retardation of the senescence of cultured human diploid fibroblasts by camosine. Exp. Cell Res. 212: 167-175.
20. RATTAN, S.I.S. & B.F.C. CLARK. 1994. Kinetin delays the onset of ageing characteristics in human fibroblasts. Biochem. Biophys. Res. Commun. 201: 665-672.
21. SHARMA, S.P., P. KAUR & S.I.S. RATTAN. 1995. Plant growth hormone kinetin delays ageing, prolongs the life span and slows down development of thc fruitfly Zaprionus paravittiger. Biochem. Biophys. Res. Commun. 216: 1067-1071.
22. SHARMA, S.P., J. KAUR & S.I.S. RATTAN. 1997. Increased longevity of kinetin-fed Zaprionus fruitflies is accompanied by their reduced fecundity and enhanced catalase activity. Biochem. Mol. Biol. Int. 41: 869-875.
23. LUCKINBILL, L.S. 1993. Prospective and retrospective tests of evolutionary theories of senescence. Arch. Gerontol. Geriatr. 16: 17-32.
24. ORR, W.C. & R.S. SOHAL. 1994. Extension of life-span by overexpression of superoxide dismulase and catalase in Drosophila melanogaster. Science 263: 1128-1130.
25. LAKOWSKI, B. & S. HEKIMI. 1996. Determination of life-span in Caenorhabditis elegans by four clock genes. Science 272: 1010-1013.
26. LARSEN, P.L. 1993. Aging and resistance to oxidative damage in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 90: 8905-8909.
27. LITHGOW, G.J., T.M. WHITE, S. MELOV & T.E. JOHNSON. 1995. Thermotolerance and extended life span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. USA 92: 7540-7544.
28. LITHGOW, G.J. 1996. Invertebrate gerontology: The age mutations of Caenorhabditis elegans. BioEssays 18: 809-815.
29. RATTAN, S.I.S. 1997. Gene therapy for ageing: Mission impossible? Eur. J. Genet. Soc. 3. 27-29.
30. RATTAN, S.I.S. & A. DERVENTZI. 1991. Altered cellular responsiveness during ageing. BioEssays 13: 601-606.
31. HAYES, S.A. & J.F. DICE. 1996. Roles of molecular chaperones in protein degradation. J. Cell Biol. 132: 255-258.
32. HOLBROOK, N.J. & R. UDELSMAN. 1994. Heat shock protein gene expression in response to physiologic stress and aging. In The Biology of Heat Shock Proteins and Molecular Chaperones. R.I. Morimoto, A. Tissières & C. Georgopoulos, Eds.: 577-593. Cold Spring Harbor Laboratory Pres. Cold Spring Harbor, NY.
33. JINDAL, S. 1996. Heat shock proteins: Applications in health and disease. Trends Biotechnol. 14: 17-20.
34. NEAFSEY, P.J. 1990. Longevity hormesis: A review. Mech. Ageing Dev. 51: 1-31.
35. POLLYCOVE, M. 1995. The issue of the decade: Hormesis. Eur. J. Nucl. Med. 22: 399-401.
36. KHAZAELI, A.A., M. TATAR, S.D. PLETCHER & J.W. CURTSINGER. 1997. Heat-induced longevity extension in Drosophila. I. Heat treatment, mortality, and thermotolerance. J. Gerontol. Biol. Sci. 52A: B48-B52.
37. RATTAN, S.I.S. 1998. Repeated mild heat shock delays ageing in cultured human skin fibroblasts. Biochem. Mol. Biol. Int. 45: 753-759.