Mechanistic study on liver tumor promoting effects of piperonyl butoxide in rats

Archives of Toxicology

Volumn 72, Issue 11, 1998, Pages 744-750

  Okamiya, Hideaki ^a   Mitsumori, Kunitoshi ^b   Onodera, Hiroshi ^b   Ito, Seiichi ^c   Imazawa, Takayoshi ^b   Yasuhara, Kazuo ^b   Takahashi, Michihito ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c Nippon Exp Med Res Inst Co L   (Japan)

Author keywords

Cell proliferating activity; Gap junctional intercellular communication; Hepatocarcinogenesis promoting mechanism; Phenobarbital; Piperonyl butoxide

Indexed keywords

PIPERONYL BUTOXIDE;

ANIMAL EXPERIMENT; ARTICLE; CARCINOGENICITY; CELL COMMUNICATION; CELL PROLIFERATION; DOSE RESPONSE; DRUG MEGADOSE; GAP JUNCTION; LIVER TOXICITY; LIVER TUMOR; NONHUMAN; PRIORITY JOURNAL; RAT; TOXICITY TESTING;

ANIMALS; BODY WEIGHT; CARCINOGENS; CELL DIVISION; CONNEXINS; CYTOCHROME P-450 CYP2B1; EATING; IMMUNOCHEMISTRY; INTERCELLULAR JUNCTIONS; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; NECROSIS; ORGAN SIZE; PHENOBARBITAL; PIPERONYL BUTOXIDE; RATS; RATS, INBRED F344; SPECIFIC PATHOGEN-FREE ORGANISMS;

ANIMALIA;

EID: 0032434363     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050569     Document Type: Article

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