Effect of plating medium and phage storage on mutant frequency and titer in the lambda ell transgenic mutation assay

Environmental and Molecular Mutagenesis

Volumn 32, Issue 4, 1998, Pages 325-330

  Zimmer, D M ^a   Harbach, P R ^a   Mattes, W B ^a   Aaron, C S ^a  

^a PFIZER INC   (United States)

Author keywords

Ell; Lambda phage; Mutation; Transgenic

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DNA DETERMINATION; GENE MUTATION; GENETIC SELECTION; MALE; MOUSE; MUTAGENESIS; MUTATION RATE; NONHUMAN; TRANSGENIC MOUSE;

ANIMALS; BACTERIOPHAGE LAMBDA; GENOTYPE; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; SPLEEN;

EID: 0032433848     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1098-2280(1998)32:4<325::aid-em5>3.0.co;2-2     Document Type: Article

References (3)

1. Herskowitz I, Hagen D. 1980. The lysis-lysogeny decision of phage lambda: Explicit programming and responsiveness. Annu Rev Genet 14:399-445.
2. Jakubczak JL, Merlino G, French JE, Muller WJ, Paul B, Adyha S, Garges S. 1996. Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage X transgene target. Proc Nat Acad Sci USA 93:9073-9078.
3. Wulff DL, Rosenberg M. 1983. Establishment of represser synthesis. In: Hendrix RW, Roberts JW, Stahl FW, Weisberg RA, eds. Lambda II. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp 53-73.