The sensitivity to DNA single strand breakage in mitochondria, but not in nuclei, of Chinese hamster V79 and variant cells correlates with their cellular sensitivity to hydrogen peroxide

Toxicology Letters

Volumn 99, Issue 1, 1998, Pages 15-22

  Kaneko, Motohisa ^a   Inoue, Fukiko ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Chinese hamster V79; DNA single strand breaks; Hydrogen peroxide; Mitochondria and nuclei; Peroxide resistant cells

Indexed keywords

HYDROGEN PEROXIDE; MITOCHONDRIAL DNA;

ANIMAL CELL; ARTICLE; CELL LYSATE; CELL NUCLEUS; CELL STRAIN V 79; CHINESE HAMSTER; DNA STRAND BREAKAGE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; SOUTHERN BLOTTING;

ALKALIES; ANIMALS; BLOTTING, SOUTHERN; CELL NUCLEUS; CHO CELLS; CHROMOSOME BREAKAGE; CRICETINAE; DNA; DNA DAMAGE; DNA, MITOCHONDRIAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYDROGEN PEROXIDE;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0032432767     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00132-5     Document Type: Article

References (15)

1. Cerutti P.A. Effects of ionizing radiation on mammalian cells. Naturwissenschaften. 61:1974;51-59.
2. Church G.M., Gilbert W. Genomic sequencing. Proc. Natl. Acad. Sci. USA. 81:1984;1991-1995.
3. Gille J.J.P., Joenje H. Cell culture models for oxidative stress. Mutation Res. 275:1992;405-414.
4. Halliwell B., Gutteridge J.M.C. Role of free radicals and catalytic metal ions in human disease. Packer L.A., Glazae N. Methods in Enzymology. 186:1990;1-85 Academic Press, London and New York.
5. Hirt B. Selective extraction of polyoma DNA from infected mouse cell cultures. J. Mol. Biol. 26:1967;365-369.
6. Kaneko M., Kodama M., Inoue F. Bimodal pattern of killing of Chinese hamster V79 variant cells by hydrogen peroxide. Free Rad. Res. 20:1994;229-239.
7. Kaneko M., Kodama M., Inoue F., Terasaki T. Mitochondrial biosynthesis controls the sensitivity of Chinese hamster cells to hydrogen peroxide. Free Rad. Res. 24:1996;299-310.
8. Kohn K.W., Erickson L.C., Ewig R.A.G., Friedman C.A. Fractionation of DNA from mammalian cells by alkaline elution. Biochemistry. 15:1976;4629-4637.
9. LeDoux S.P., Wilson G.L., Bohr V.A. Mitochondrial DNA repair and cell injury. Lash L.H., Jones D.P. Methods in Toxicology. 2:1993;461-476 Academic Press, London and New York.
10. Luo Y., Han Z., Chin S., Linn S. Three chemically distinct types of oxidants formed by iron-mediated Fenton reactions in the presence of DNA. Proc Natl Acad Sci USA. 91:1994;12438-12442.
11. Minty A. J., Caravatti M., Robert B., Cohen A., Daubas P., Weydert A., Gros F., Buckingham E. Mouse actin messenger RNAs. J. Biol. Chem. 256:1981;1008-1014.
12. Nakayama T., Kaneko M., Kodama M., Nagata C. Cigarette smoke induces DNA single strand breaks in human cells. Nature. 314:1985;462-464.
13. Sestili P., Cattabeni F., Cantoni O. The induction/loss of the oxidant-resistant phenotype of Chinese hamster ovary (CHO) cell variants does not correlate with sensitivity to DNA single strand breakage by hydrogen peoxide. Biochem. Pharmacol. 48:1994;1701-1706.
14. Suzuki H., Wakana S., Yonekawa H., Moriwaki K., Sakurai S., Nevo E. Variations in ribosomal DNA and mitochondrial DNA among chromosomal species of subterranean mole rats. Mol. Biol. Evol. 13:1996;85-92.
15. Yakes F.M., Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA. 94:1997;514-519.