Angiotensin IV receptor-mediated activation of lung endothelial NOS is associated with vasorelaxation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 275, Issue 6 19-6, 1998, Pages

  Patel, Jawaharlal M ^a,b   Martens, Jeffrey R ^b   Li, Yong D ^b   Gelband, Craig H ^b   Raizada, Mohan K ^b   Block, Edward R ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Endothelium; Nitric oxide synthase

Indexed keywords

1 (4 AMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDROIMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN II [1 SARCOSINE 8 ISOLEUCINE]; ANGIOTENSIN II [3-8]; ANGIOTENSIN RECEPTOR; CYCLIC GMP; LOSARTAN; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTERY ENDOTHELIUM; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; RECEPTOR BINDING; RECEPTOR BLOCKING; SWINE; VASODILATATION;

EID: 0032432573     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1998.275.6.l1061     Document Type: Article

References (15)

1. Aisaka, K., S. S. Gross, O. W. Griffith, and R. Levi. L-arginine availability determines the duration of acetylcholine-induced systemic vasodilation in vivo. Biochem. Biophys. Res. Commun. 63: 710-717, 1989.
2. Barhul, A. Arginine: biochemistry, physiology, and therapeutic implications. JPENJ. Parenter. Enteral Nutr. 10: 227-238, 1986.
3. Bernier, S. G., G. Servant, M. Boudreau, A. Fournier, and G. Guillemette. Characterization of a binding site for angiotensin IV on bovine aortic endothelial cells. Eur. J. Pharmacol. 291: 191-200, 1995.
4. Chang, D. Y., B. J. DeWitt, E. L. Dent, B. D. Nossaman, and P. J. Kadowitz. Analysis of responses to angiotensin IV in the pulmonary vascular bed of the cat. Eur. J. Pharmacol. 261: 223-227, 1994.
5. Czekalski, S., D. Chansel, S. Vandermeersch, P. Ronco, and R. Ardaillou. Evidence of angiotensin IV receptors in human collecting duct cells. Kidney Int. 50: 1125-1131, 1996.
6. Davis, M. G., G. J. Fulton, and P. O. Hagen. Clinical biology of nitric oxide. Br. J. Surg. 82: 1598-1610, 1995.
7. Dinh-Xuan, A. T., T. W. Higenbottam, C. A. Celland, J. Pepke-Zaba, G. Cremana, A. Y. Butt, S. R. Large, F. C. Wells, and J. Wallcork. Impairment of endothelium-dependent pulmonary artery relaxation in chronic obstructive lung disease. N. Engl. J. Med. 324: 1539-1547, 1991.
8. Eddahibi, S., S. Adnot, C. Carville, Y. Blouguit, and B. Raffestin. L-Arginine restores endothelium-dependent relaxation in the pulmonary circulation of chronically hypoxic rats. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): L194-L200, 1992.
9. Fishman, A. P. Endothelium: a distributed organ of diverse capabilities. Ann. NY Acad. Sci. 401: 1-8, 1982.
10. Garcia-Cardena, G., R. Fan, D. F. Sternt, J. Liu, and W. C. Sessa. Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. J. Biol. Chem. 271: 27237-27240, 1996.
11. Giaid, A., and D. Saleh. Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 333: 214-221, 1995.
12. Goodfriend, T. L., M. E. Elliott, and K. J. Catt. Angiotensin receptors and their antagonists. N. Engl. J. Med. 334: 1649-1654, 1996.
13. Haberl, R. L., P. J. Decker, and K. M. Einhaupl. Angiotensin degradation products mediate endothelium-dependent dilation of rabbit brain arterioles. Circ. Res. 68: 1621-1627, 1991.
14. Hall, K. L., S. Venkateswaran, J. M. Hanesworth, M. E. Schelling, and J. W. Harding. Characterization of a functional angiotensin IV receptor on coronary microvascular endothelial cells. Regul. Pept. 58: 107-115, 1995.
15. Hanesworth, J. M., M. F. Sardinia, L. T. Krebs, K. L. Hall, and J. W. Harding. Elucidation of a specify binding site for angiotensin II(3-8), angiotensin IV, in mammalian heart membranes. J. Pharmacol. Exp. Ther. 266: 1036-1042, 1993.