Enhanced osteopontin expression and macrophage infiltration in MRL-Fas(lpr) mice with lupus nephritis

Autoimmunity

Volumn 28, Issue 3, 1998, Pages 139-150

  Wüthrich, Rudolf P ^a   Fan, Xiaohong ^a   Ritthaler, Theresia ^a   Sibalic, Vladimir ^a   Yu, Da Jiang ^a   Loffing, Jan ^a   Kaissling, Brigitte ^a  

^a NONE

Author keywords

Cytokines; Lupus nephritis; Macrophages; Mice; Osteopontin

Indexed keywords

CALCITRIOL; MESSENGER RNA; OSTEOPONTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOFLUORESCENCE; IN SITU HYBRIDIZATION; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EPITHELIUM; LUPUS ERYTHEMATOSUS NEPHRITIS; MACROPHAGE; MOUSE; NONHUMAN; NORTHERN BLOTTING;

EID: 0032432392     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.3109/08916939808996282     Document Type: Article

References (40)

1. Butler, W.T. The nature and significance of osteopontin. Connect. Tissue Res. 1989; 23: 123-36.
2. Denhardt, D.T. and Guo, X. Osteopontin: a protein with diverse functions. FASEB J. 1993; 7: 1475-82.
3. Brown, L.F., Berse, B., Van de Water, L. et al. Expression and distribution of osteopontin in human tissues: wide-spread association with luminal epithelial surfaces. Mol. Biol. Cell 1992; 3: 1169-80.
4. Lopez, C.A., Hoyer, J.R., Wilson, P.D., Waterhouse, P. and Denhardt, D.T. Heterogeneity of osteopontin expression among nephrons in mouse kidneys and enhanced expression in sclerotic glomeruli. Lab. Invest. 1993; 69: 355-63.
5. Kleinman, J.G., Beshensky, A., Worcester, E.M. and Brown, D. Expression of osteopontin, a urinary inhibitor of stone mineral crystal growth, in rat kidney. Kidney Int. 1995: 47: 1585-96.
6. Madsen, K.M., Zhang, L., Shamat, A.A., Siegfried, S. and Cha, J.-H. Ultrastructural localization of osteopontin in the kidney: induction by lipopolysaccharide. J. Am. Soc. Nephrol. 1997; 8: 1043-53.
7. Kohri, K., Nomura, S., Kitamura, Y. et al. Structure and expression of the mRNA encoding urinary stone protein (osteopontin). J. Biol. Chem. 1993; 268: 15180-4.
8. Hoyer, J.R. Uropontin in urinary calcium stone formation. Miner. Electrolyte Metab. 1994; 20: 385-92.
9. Singh, R.P., Patarca, R., Schwartz, J., Singh, P. and Cantor, H. Definition of a specific interaction between the early T lymphocyte activation 1 (Eta-1) protein and murine macrophages in vitro and its effects upon macrophages in vivo. J. Exp. Med. 1990; 171: 1931-42.
10. Yamamoto, S., Nasu, K., Ishida, T. et al. Effect of recombinant osteopontin on adhesion and migration of P388D1 cells. Ann. N. Y. Acad. Sci. 1995; 760: 378-80.
11. Liaw, L., Almeida, M., Hart, C.E., Schwartz, S.M. and Giachelli, C.M. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ. Res. 1994; 74: 214-24.
12. Pichler, R., Giachelli, C.M., Lombardi, D. et al. Tubulointerstitial disease in glomerulonephritis. Potential role of osteopontin (uropontin). Am. J. Pathol. 1994; 144: 915-26.
13. Giachelli, C.M., Pichler, R., Lombardi, D. et al. Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. Kidney Int. 1994; 45: 515-24.
14. Eddy, A.A. and Giachelli, C.M. Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria. Kidney Int. 1995; 47: 1546-57.
15. Boswell, J.M., Yui, M.A., Burt, D.W. and Kelley, V.E. Increased tumor necrosis factor and IL-1β gene expression in the kidneys of mice with lupus nephritis. J. Immunol. 1988; 141: 3050-4.
16. lpr mice with lupus nephritis. Inflammation 1997; 21: 109-18.
17. Lemay, S., Mao, C. and Singh, A.K. Cytokine gene expression in the MRL/lpr model of lupus nephritis. Kidney Int. 1996; 50: 85-93.
18. Wüthrich, R.P., Jevnikar, A.M., Takei, F., Glimcher, L.H. and Kelley, V.E. Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis. Am. J. Pathol. 1990; 136: 441-50.
19. Wüthrich, R.P. Vascular cell adhesion molecule-1 (VCAM-1) expression in murine lupus nephritis. Kidney Int. 1992; 42: 903-14.
20. Worcester, E.M., Blumenthal, S.S., Beshensky, A.M. and Lewand, D.L. The calcium oxalate crystal growth inhibitor protein produced by mouse kidney cortical cells in culture is osteopontin. J. Bone Miner. Res. 1992; 7: 1029-36.
21. McKnight, A.J., Macfarlane, A.J., Dri, P., Turley, L., Willis, A.C. and Gordon, S. Molecular cloning of F4/80, a murine macrophage-restricted cell surface glycoprotein with homology to the G-protein-linked transmembrane 7 hormone receptor family. J. Biol. Chem. 1996; 271: 486-9.
22. Craig, A.M., Smith, J.H. and Denhardt, D.T. Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. J. Biol. Chem. 1989; 264: 9682-9.
23. Benz, P.S., Fan, X.H. and Wüthrich, R.P. Enhanced tubular epithelial CD44 expression in MRL-lpr lupus nephritis. Kidney Int. 1996; 50: 156-63.
24. Chirgwin, J.M., Przybyla, A.E., MacDonald, R.J. and Rutter, W.J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294-9.
25. Haverty, T.P., Kelly, C.J., Hines, W.H. et al. Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis. J. Cell Biol. 1988; 107: 1359-68.
26. Patarca, R., Saavedra, R.A. and Cantor, H. Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene. Critical Rev. Immunol. 1993; 13: 225-46.
27. Cantor, H. The role of Eta-1/osteopontin in the pathogenesis of immunological disorders. Ann. N. Y. Acad. Sci. 1995; 760: 143-50.
28. Patarca, R., Freeman, G.J., Singh, R.P. et al. Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J. Exp. Med. 1989; 170: 145-61.
29. Ono, M., Yamamoto, T. and Nose, M. Allelic difference in the nucleotide sequence of the Eta-1/Op gene transcript. Mol. Immunol. 1995; 32: 447-8.
30. Andrews, B.S., Eisenberg, R.A., Theofilopoulos, A.N. et al. Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. J. Exp. Med. 1978; 148: 1198-215.
31. Theofilopoulos, A.N., Prud'homme, G.J. and Dixon, F.J. Autoimmune aspects of systemic lupus erythematosus. Concepts Immunopathol. 1985; 1: 190-218.
32. Kelley, V.E. and Roths, J.B. Increase in macrophage Ia expression in autoimmune mice: role of the lpr gene. J. Immunol. 1982; 129: 923-5.
33. Bloom, R.D., Florquin, S., Singer, G.G., Brennan, D.C. and Kelley, V.R. Colony stimulating factor-1 in the induction of lupus nephritis. Kidney Int. 1993; 43: 1000-9.
34. Pichler, R.H., Franceschini, N., Young, B.A. et al. Pathogenesis of cyclosporine nephropathy: roles of angiotensin II and osteopontin. J. Am. Soc. Nephrol. 1995; 6: 1186-96.
35. Young, B.A., Burdmann, E.A., Johnson, R.J. et al. Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity. Kidney Int. 1995; 48: 439-48.
36. Watson, M.L., Rao, J.K., Gilkeson, G.S. et al. Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J. Exp. Med. 1992; 176: 1645-56.
37. Shirai, A. and Klinman, D.M. The genetic basis of autoimmune disease in MRL-lpr/lpr mice. Int. Rev. Immunol. 1994; 11: 179-92.
38. Patarca, R., Wei, F.Y., Singh, P., Morasso, M.I. and Cantor, H. Dysregulated expression of the T cell cytokine Eta-1 in CD4-8-lymphocytes during the development of murine autoimmune disease. J. Exp. Med. 1990; 172: 1177-83.
39. Lampe, M.A., Patarca, R., Iregui, M.V. and Cantor, H. Polyclonal B cell activation by the Eta-1 cytokine and the development of systemic autoimmune disease. J. Immunol. 1991; 147: 2902-6.
40. Yokoyama, H., Kreft, B. and Kelley, V.R. Biphasic increase in circulating and renal TNF-α in MRL-lpr mice with differing regulatory mechanisms. Kidney Int. 1995; 47: 122-30.