Automatic quantification of immunohistochemically stained cell nuclei based on standard reference cells

Analytical Cellular Pathology

Volumn 17, Issue 2, 1998, Pages 111-123

  Ranefall, Petter ^a   Wester, Kenneth ^b   Andersson, Ann Catrin ^b   Busch, Christer ^b   Bengtsson, Ewert ^a  

^a Centre for Image Analysis   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Automatic quantification; Control cells; Image analysis; Immunohistochemically stained cell nuclei

Indexed keywords

ARTICLE; BLADDER CARCINOMA; CELL LABELING; CELL NUCLEUS; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; LABORATORY AUTOMATION; PRIORITY JOURNAL; STAINING;

EID: 0032431788     PISSN: 09218912     EISSN: None     Source Type: Journal    
DOI: 10.1155/1998/195432     Document Type: Article

References (34)

1. D.C. Allred, G.M. Clark, R. Elledge, S.A. Fuqua, R.W. Brown, G.C. Chamness, C.K. Osborne and W.L. McGuire, Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer, J. Natl. Cancer Inst. 85 (1993), 200-206.
2. H. Battifora, J. Esteban, S. Bacus and P. Mehta, Quantitative immunocytochemistry on paraffin-embedded tissues. The quicgel method, Lab. Invest. 62 (1990), 8a.
3. S. Biesterfeld, U. Veuskens, F.J. Schmitz, B.A. Takyi and A. Bocking, Interobserver reproducibility of immunocytochemical estrogen- and progesterone receptor status assessment in breast cancer, Anticancer Res. 16 (1996), 2497-2500.
4. S. Binks, C.A. Clelland, J. Ronan and J. Bell, p53 gene product expression in resected non-small cell carcinoma of the lung, with studies of concurrent cytological preparations and microwave antigen retrieval, J. Clin. Pathol. 50 (1997), 320-323.
5. F.T. Bosman, A.F. de Goeij and M. Rousch, Quality control in immunocytochemistry: experiences with the oestrogen receptor assay, J. Clin. Pathol. 45 (1992), 120-124.
6. V.K. Boumeester, P. van Loenen, E.M. de Bruijn and S.C.H. Logmans, Quality control of immunocytochemical staining of effusions using a standardized method of cell processing, Acta Cytol. 40 (1996), 475-479.
7. P. Brandtzaeg and T.O. Rognum, Evaluation of nine different fixatives. 2. Preservation of igg, iga and secretory component in an artificial immunohistochemical test substrate, Histochemistry 81 (1984), 213-219.
8. B.L. Cameron, J.A. Butler, J. Rutgers, H.I. Vargas, M. Purtell and B. Sheppard, Immunohistochemical determination of the estrogen receptor content of gastrointestinal adenocarcinomas, Am. Surg. 58 (1992), 758-760.
9. K.R. Castleman, Digital Image Processing, Prentice-Hall, 1979.
10. N. el Badawy, C. Cohen, P.B. Derose, I.J. Check and D. Sgoutas, Immunohistochemical progesterone receptor assay. Measurement by image analysis, Am. J. Clin. Pathol. 96 (1991), 704-710.
11. K.C. Gatter, C. I. Oakley lecture (1989). Diagnostic immunocytochemistry: achievements and challenges, J. Pathol. 159 (1989), 183-190.
12. L.C. Happerfield, L.G. Bobrow, R. Bains and K.D. Miller, Peroxidase labelling immunocytochemistry: a comparison of eleven commercially-available avidin-biotin systems, Br. J. Biomed. Sci. 50 (1993), 21-26.
13. G. Haroske, V. Dimmer, K. Friedrich, W. Meyer, B. Thieme, F. Theissig and K.D. Kunze, Nuclear image analysis of immunohistochemically stained cells in breast carcinomas, Histochem. Cell. Biol. 105 (1996), 479-485.
14. I. Joliffe, Principal Component Analysis, Springer-Verlag, 1986.
15. E.W. Kay, C.J. Walsh, M. Cassidy, B. Curran and M. Leader, C-erbb-2 immunostaining: problems with interpretation, J. Clin. Pathol. 47 (1994), 816-822.
16. D.F. Kurtycz, R. Logrono, M. Leopando, A. Slattery and S.L. Inborn, Immunocytochemistry controls using cell culture, Diagn. Cytopathol. 17 (1997), 74-79.
17. L.I. Larsson, Tissue preparation methods for light microscopic immunohistochemistry, Appl. Immunohistochem. 1 (1993), 2-16.
18. H.C. Lin, A.V. Sotnikov, L. Fosdick, R.M. Bostick and W.C. Willett, Quantification of proliferating cell nuclear antigen in large intestinal crypt by computer-assisted image analysis, Cancer Epidemiol. Biomarkers Prev. 5 (1996), 109-114.
19. P.U. Malmström, Prognosis of transitional cell bladder carcinoma. With special reference to abh blood group isoantigen expression and DNA analysis, Scand. J. Urol. Nephrol. Suppl. 112 (1988), 1-55.
20. P.-U. Malmström, K. Wester, J. Vasko and C. Busch, Expression of proliferating cell nuclear antigen (PCNA) in urinary bladder carcinoma. Evaluation of antigen retrieval methods, APMIS 100 (1992), 988-992.
21. M. Miettinen, Immunohistochemistry of solid tumors. Brief review of selected problems, APMIS 98 (1990), 191-199.
22. O. Milvang, An adaptive algorithm for color image quantization, in: Proceedings of the 5th Scandinavian Conference on Image Analysis, Stockholm, Sweden, 1987, Vol. 1, 1987, pp. 43-47.
23. P. Ranefall, L. Egevad, B. Nordin and E. Bengtsson, A new method for segmentation of colour images applied to immunohistochemically stained cell nuclei, Analytical Cellular Pathology 15(3) (1997), 145-156.
24. P. Ranefall, K. Wester and E. Bengtsson, Automatic quantification of immunohistochemically stained cell nuclei using unsupervised image analysis, Analytical Cellular Pathology 16(1) (1998), 29-43.
25. V. Ravn, B.B. Rasmussen, L. Hojholt, M. Barfoed, I. Heiberg and S.M. Thorpe, Reproducibility of subjective immunohistochemical estrogen- and progesterone receptor determination in human endometrium, Pathol. Res. Pract. 189 (1993), 1015-1022.
26. P. Sallinen, H. Haapasalo, T. Kerttula, I. Rantala, H. Kalimo, Y. Collan, J. Isola and H. Helin, Sources of variation in the assessment of cell proliferation using proliferating cell nuclear antigen immunohistochemistry, Anal. Quant. Cytol. Histol. 16 (1994), 261-268.
27. D.S. Schultz, R.L. Katz, S. Patel, D. Johnston and N.G. Ordonez, Comparison of visual and cas-200 quantitation of immunocytochemical staining in breast carcinoma samples, Anal. Quant. Cytol. Histol. 14 (1992), 35-40.
28. S.R. Shi, R.J. Cote and C.R. Taylor, Antigen retrieval immunohistochemistry: past, present, and future, J. Histochem. Cytochem. 45 (1997), 327-343.
29. C.R. Taylor, An exaltation of experts: concerted efforts in the standardization of immunohistochemistry, Hum. Pathol. 25 (1994), 2-11.
30. C.R. Taylor, The status of immunohistochemical studies in lymphoma diagnosis, Biotech. Histochem. 72 (1997), 62-77.
31. C.R. Taylor, S.R. Shi, B. Chaiwun, L. Young, S.A. Imam and R.J. Cote, Strategies for improving the immunohistochemical staining of various intranuclear prognostic markers in formalin-paraffin sections: androgen receptor, estrogen receptor, progesterone receptor, p53 protein, proliferating cell nuclear antigen, and ki-67 antigen revealed by antigen retrieval techniques, Hum. Pathol. 25 (1994), 263-270.
32. P.J. van Diest, D.R. Weger and J. Lindholm, Reproducibility of subjective immunoscoring of steroid receptors in breast cancer, Anal. Quant. Cytol. Histol. 18 (1996), 351-354.
33. J.H. Williams, B.L. Mepham and D.H. Wright, Tissue preparation for immunocytochemistry, J. Clin. Pathol. 50 (1997), 422-428.
34. L.E. Wold, D.J. Corwin, R.R. Rickert, N. Pettigrew and R.R. Tubbs, Interlaboratory variability of immunohistochemical stains. Results of the cell markers survey of the college of American pathologists, Arch. Pathol. Lab. Med. 113 (1989), 680-683.