Activation of a procarcinogen by reduction: Cr6+→Cr5+→Cr4+→Cr3+. A case study by electron spin resonance (ESR/PMR)

Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews

Volumn 16, Issue 2, 1998, Pages 135-148

  Chiu, Arthur ^a   Chiu, Nancy ^b   Shi, Xianglin ^c   Beaubier, Jefferson ^a   Dalal, N S ^d  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b National Institute of Arthritis Musculoskeletal and Skin Diseases   (United States)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^d FLORIDA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN;

CHEMICAL ANALYSIS; CHEMICAL CARCINOGENESIS; CHEMICAL MUTAGENESIS; ELECTRON SPIN RESONANCE; MALIGNANT NEOPLASTIC DISEASE; REVIEW;

EID: 0032431387     PISSN: 10590501     EISSN: None     Source Type: Journal    
DOI: 10.1080/10590509809373504     Document Type: Review

References (41)

1. Petrilli FL, DeFlora S, 1977. Toxicity and mutagenicity of hexavalent chromium in Salmonella typhimurium. Appl Environ Microbiol 33;805-9
2. Petrilli FL, DeFlora S, 1978. Oxidation of inactive trivalent chromium to the mutagenic hexavalent form Mutat Res 58; 167-78
3. Petrilli FL, DeFlora S, 1978. Metabolic deactivation of hexavalent chromium mutagenicity Mutat Res 54;139-47.
4. Bianchi V, Celott L, Lanfranchi G, Majone F, Marin G, Montaldi A, Sponza G, Tamino G, Venier P, Zantedeschi A, Levis, AG. 1983. Mutat Res 117;279-300
5. Tsuda H, Kato K, 1977. Chromosomal aberrations and morphological transformation in hamster embryonic cells treated with potassium dichromate in vitro. Mutat Res 46;87-94
6. Wetterhahn KE, Cupo DY, Connett PH, 1984. The interaction of chromium with cellular components in vitro. Trace Subst Envn Health 18;154
7. Miller EC, 1978. Some current perspectives on chemical carcinogenesis in humans and experimental animals: presidential address. Cancer Res 38; 1479-96
8. Miller EC, Miller JA, 1981. Searches for ultimate chemical carcinogens and their reactions with cellular macromolecules. Cancer 47; 2327-45.
9. Tsapakos MJ, Wetterhahn KE, 1983. The interaction of chromium with nucleic acid Chem Biol Interact 46;265-77
10. Jennette KW, 1982. Microsomal reduction of the carcinogen Chromate produces chromium (V) J Am Chem Soc 108;874-5
11. Shi XL, Dalal NS, 1989. Chromium(V) and hydroxyl radical formation during the Glutathione reductase catalyzed reduction of chromium(VI) Biochem Biophys Res Comm 163(1);627-34
12. Aiyar J, Berkovits HJ, Floyd RA, Wetterhahn KE, 1990. Reaction of chromium (V) with hydrogen peroxide in the presence of Glutathione; reactive intermediates and resulting DNA damage Chem Res Toxicol 3;595-603
13. Aiyar J, Borges KM, Floyd RA, Wetterhahn KE, 1990. Role of chromium(V) Glutathione thiyl radical and hydroxyl radical intermediates in chromium (VI)-induced DNA damage Toxicol Envirn Chem 22;135-148
14. Sugiyama M, Ando A, Ogura R, 1989. Effects of vitamin E on survival Glutathione reductase and formation of chromium (V) in Chinese hamster V-79 cell treated with sodium dichromate (VI) Carcinogenicity 40;737-41.
15. Cupo DY, Wetterhahn KE, 1985. Modification of Cr(VI)induced DNA damage by glutathione and cytochrome P-450 in chicken embryo hepatocytes Proc Natl Acad Sci USA 82; 6755-6759
16. Klein CB, Frenkel K, Costa M, 1991. The role of oxidative processes in metal carcinogenesis Chem Res Toxicol 4;592-604.
17. Kasprzak KS, 1991. The role of oxidative damage in metal carcinogenesis Chem Res Toxicol 4; 604-615
18. Liu KJ, Jiang, JJ, Shi, XL, Gabrys, H, Wakczaj, T, Swartz HM, 1995. Low frequency EPR study of Cr(V) formation from Cr(VI) in living plants. Biochem Biophys Res Comm 206(3); 829-834
19. 6+ carcinogenicity Biochem Biophys Res Comm 235;54-8.
20. Liu KJ, Shi, XL, Jiang, JJ, Goda, F, Dalal, N, Swartz HM, 1995. Chromate induced Cr(V) formation in live mice and its control by cellular antioxidants; an L-band EPR study Arch Biochem Biophys 323(1);33-39
21. Craf E, Mahoney, JR, Bryant, RG, Eaton JW, 1984. Iron catalyzed hydroxyl radical formation stringent requirement for free iron coordination site J Biol Chem 259;3620-4
22. Shi, XL; Dalal N, 1994. Generation of hydroxyl radical by Chromate in biologically relevant systems; role of Cr(V) complexes versus Tetraperoxochromate(V) Envn Healths Persp 102 Supp3;231-6
23. 6+by whole live mice Ann Clin Lab Sci 26(2);176-84
24. Liu KJ, Jiang, JJ, Swartz, HM, Shi XL, 1995. Low frequency EPR detection of chromium (V) formation by Chromium (VI) reduction in whole live mice Arch Biochem Biophys 313(2); 248-252
25. Shi X.L., Dong ZA, Dalal NS, Gannett PM, 1994. Chromate mediated free radical generation from cysteine, penicillamine, hydrogen peroxide, and lipid peroxides Biochim Biophys Acta 1226;65-74
26. Meister A, Anderson ME, 1983. Glutathione Ann Rev Biochem 52;711-60
27. Shi XL, Dalal NS, 1988. On the mechanism of chromate reduction by Glutathione: ESR evidence for the glutathionyl radical and an isolable Cr(V) intermediate. Biochem Biophys Res Comm 156(1);137-142
28. 3+ Arch Biochem Biophys 302(1);294-9.
29. Shi XL, Dalal NS, 1990. On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated Cr(V) species Arch Biochem Biophys 277;342-350; 281-90-5
30. 4+ mediated Fenton-like reaction Carcinogenesis15(11); 2475-8
31. 5+mediated radical generation and deoxyguanine hydroxylation:ESR and HPLC evidence Arch Biochem Biophys 293(2);281-6
32. Shi XL, Dalal NS , 1990. Evidence for a Fenton-type mechanism for the generation of •OH radicals in the reduction of Cr(VI) in cellular media Arch Biochem Biophys 281,90-5
33. Xu J; Bubley GJ; Detrick B; Blankenship LJ; Patierno SR, 1996. Chromium(VI) treatment of normal human lung cells results in guanine-specific DNA polymerase arrest, DNA-DNA cross-links and S-phase blockade of cell cycle.Carcinogenesis Jul;17(7):1511-7
34. Shi XL, Dalal NS , 1990. NADPH dependent flavoenzyme catalyzed one electron reduction of metal ions and molecular oxygen and generate hydroxyl radicals. FEBS Lett 276;189-91
35. Shi XL, Dalal NS , 1990. Spin trapping detection of hydroxyl radicals in the reaction of Cr(V) complexes with hydrogen peroxide Free Radical Res Comm 10,17-26
36. Hamilton JW, Wetterhahn KE, 1989. Differential effects of chromium(VI) on constitutive and inducible gene expression in chick embryo liver in vivo and correlation with chromium (VI) induced DNA damage. Mol Carcinogenesis 2;274-286
37. Furono K; Suetsuga T; Sugihara N, 1996. Effects of metal ions on lipid peroxidation in cultured rat hepatocytes loaded with α-linolenic acid. J Toxicol Environ Health Jun 7;48(2):121-9
38. 6+ by α-lipoic acid and related hydroxyl radical generation, dG hydroxylation and nuclear transcription factor-κB activation. Arch Biochem Biophys 338(2);165-72
39. 6+ induced nuclear factor-κB activation in intact cells via free radical reactions Carcinogenesis 16(10);2401-5.
40. Wedrychowski A, Ward WS, Schmidt WN, Hnilica LS, 1985. Chromium induced cross linking of nuclear proteins and DNA J Biol Chem 260;7150-55
41. 8. J Chem Phys 74; 1916-23.