Effect of rush immunotherapy on airway inflammation and airway hyperresponsiveness after bronchoprovocation with allergen in asthma

Journal of Allergy and Clinical Immunology

Volumn 102, Issue 6 II, 1998, Pages 927-934

  Kohno, Yasurou ^a   Minoguchi, Kenji ^a   Oda, Naruhito ^a   Yokoe, Takuya ^a   Yamashita, Naomi ^b   Sakane, Tsuyoshi ^b   Adachi, Mitsuru ^a  

^a SHOWA UNIVERSITY   (Japan)

^b ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Airway hyperresponsiveness; Airway inflammation; Asthma; Eosinophil; IL 5; Late asthmatic response; Mast cell; Rush immunotherapy

Indexed keywords

HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; INTERLEUKIN 5;

ADULT; ALLERGIC ASTHMA; ALLERGY; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EOSINOPHIL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOTHERAPY; INFLAMMATION; MALE; MAST CELL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; T LYMPHOCYTE; TREATMENT OUTCOME;

ADULT; ALLERGENS; ANTIGENS, DERMATOPHAGOIDES; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; BRONCHITIS; DESENSITIZATION, IMMUNOLOGIC; FEMALE; FORCED EXPIRATORY VOLUME; GLYCOPROTEINS; HUMANS; INTERLEUKIN-5; MALE; RANDOM ALLOCATION; T-LYMPHOCYTES;

EID: 0032429819     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0091-6749(98)70330-6     Document Type: Article

References (33)

1. Abramson M, Puy R, Weiner J. Is allergen immunotherapy effective in asthma? A meta-analysis of randomized clinical trials. Am J Respir Crit Care Med 1995;151:969-74.
2. Torres Costa JC, Placido JL, Moreira Silva JP, Delgado L, Vaz M. Effects of immunotherapy on symptoms, PEFR, spirometry, and airway responsiveness in patients with allergic asthma to house-dust mites (D pteronyssinus) on inhaled steroid therapy. Allergy 1996;51:238-44.
3. Peroni DG, Piacentini GL, Martinati LC, Warner JO, Boner AL. Double-blind trial of house-dust mite immunotherapy in asthmatic children resident at high altitude. Allergy 1995;50:925-30.
4. Adkinson NF Jr, Eggleston PA, Eney D, Goldstein EO, Schuberth KC, Bacon JR, et al. A controlled trial of immunotherapy for asthma in allergic children. N Engl J Med 1997;336:324-31.
5. Charlesworth EN. Late-phase inflammation: influence on morbidity. J Allergy Clin Immunol 1996;98:S291-7.
6. Drazen JM, Ann JP, Austen KF. Sorting out the cytokines of asthma. J Exp Med 1996;183:1-5.
7. Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986;136:2348-57.
8. Romagnani S. Lymphokine production by human T cells in disease states. Annu Rev Immunol 1994;12:227-57.
9. Robinson DS, Hamid Q, Ying S, Tsicopoulos A, Barkans J, Bentley AM, et al. Predominant Th2-like bronchoalveolar T-lymphocyte population in atopic asthma. N Engl J Med 1992;326:298-304.
10. Nagata M, Shibasaki M, Sakamoto Y, FukudaT, Makino S, Yamamoto K, et al. Specific immunotherapy reduces the antigen-dependent production of eosinophil chemotactic activity from mononuclear cells in patients with atopic asthma. J Allergy Clin Immunol 1994;94:160-6.
11. Yasueda H, Akiyama K, Maeda Y, Hayakawa T, Kaneko F, Hasegawa M, et al. An enzyme-linked immunosorbent assay (ELISA) for the quantitation of sugi pollen and Dermatophagoides mite allergens and its application for standardization of allergen extracts. Jap J Allergol 1991;40:1218-25
12. Brockow K, Kiehn M, Riethrnuller C, Vieluf D, Berger J, Ring J. Efficacy of antihistamine pretreatment in the prevention of adverse reactions to Hymenoptera immunotherapy: a prospective, randomized, placebo-controlled trial. J Allergy Clin Immunol 1997;100:458-63.
13. Pin I, Gibson PG, Kolendowicz R, Girgris-Gabardo A, Denburg JA, Hargreave FE, et al. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992;47:25-9.
14. Bousquet J, Chanez P, Chanal I, Michel FB. Comparison between RAST and Pharmacia CAP system: a new automated specific IgE assay. J Allergy Clin Immunol 1990;85:1039-43.
15. Peterson CGB, Enander I, Nystrand J, Anderson AS, Nilsson L, Venge P. Radioimmunoassay of human eosinophil cationic protein (ECP) by an improved method; establishment of normal levels in serum and turnover in vivo. Clin Exp Allergy 1991;21:561-7.
16. Smith H. Asthma, inflammation, eosinophils, and bronchial hyperresponsiveness. Clin Exp Allergy 1992;22:187-97.
17. Bochner BS, Undem BJ, Lichtenstein LM. Immunological aspects of allergic asthma. Annu Rev Immunol 1994;12:295-335.
18. Kung TT, Stelts D, Zurcher JA, Jones H, Umland SP, Kreutner W, et al. Mast cells modulate allergic pulmonary eosinophilia in mice. Am J Respir Cell Mol Biol 1995;12:404-9.
19. Shalit M, Levi-Schaffer F Challenge of mast cells with increasing amounts of antigen induces desensitization. Clin Exp Allergy 1995;25:896-902.
20. Secrist H, Chelen CJ, Wen Y, Marshall JD, Umetsu DT. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J Exp Med 1993;178:2123-30.
21. Jutel M, Pichler WJ, Skrbic D, Urwyler A, Dahinden C, Muller UR. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-γ secretion in specific allergen-stimulated T cell cultures. J Immunol 1995;154:4187-94.
22. O'Brien RM, Byron KA, Varigos GA, Thomas WR. House dust mite immunotherapy results in a decrease in Der p2-specific IFN-γ and IL-4 expression by circulating T lymphocytes. Clin Exp Allergy 1997;27:46-51.
23. Ebner C, Siemann U, Bohle B, Willheim M, Wiedermann U, Schenk S, et al. Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T-cell clones specific for Phi p 1, a major grass pollen allergen. Clin Exp Allergy 1997;27:1007-15.
24. Maestrelli P, Saetta M, Di Stefano A, Calcagni PG, Turato G, Ruggieri MP, et al. Comparison of leukocyte counts in sputum, bronchial biopsies, and bronchoalveolar lavage. Am J Respir Crit Care Med 1995;152:1926-31.
25. Keatings VM, O'Connor BJ, Wright LG, Huston DP, Corrigan CJ, Barnes PJ. Late response to allergen is associated with increased concentrations of tumor necrosis factor-α and IL-5 in induced sputum. J Allergy Clin Immunol 1997;99:693-8.
26. Durham SR, Ying S, Varney VA, Jacobson MR, Sudderick RM, Mackay IS, et al. Grass pollen immunotherapy inhibits allergen-induced infiltration of CD4+T lymphocytes and eosinophils in the nasal mucosa and increases the number of cells expressing messenger RNA for interferon-γ. J Allergy Clin Immunol 1996;97:1356-65.
27. Nish WA, Charlesworth EN, Davis TL, Whisman BA, Valtier S, Charlesworth MG, et al. The effect of immunotherapy on the cutaneous late phase response to antigen. J Allergy Clin Immunol 1994;93:484-93.
28. Iliopoulos O, Proud D, Adkinson NF Jr, Creticos PS, Norman PS, Kagey-Sobotka A, et al. Effects of immunotherapy on the early, late, and rechallenge nasal reaction to provocation with allergen: changes in inflammatory mediators and cells. J Allergy Clin Immunol 1991;87:855-66.
29. Van Bever HP, Stevens WJ. Suppression of the late asthmatic reaction by hyposensitization in asthmatic children allergic to house dust mite (Dermatophagoides pteronyssinus). Clin Exp Allergy 1989;19:399-404.
30. Varney VA, Hamid QA, Gaga M, Ying S, Jacobson M, Frew AJ, et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993;92:644-51.
31. James AL, Pare PD, Hogg JC. The mechanics of airway narrowing in asthma. Am Rev Respir Dis 1989;139:242-6.
32. Olivieri D, Chetta A, Del Donno M, Bertorelli G, Casalini A, Pesci A, et al. Effect of short-term treatment with low-dose inhaled fluticasone proprionate on airway inflammation and remodeling in mild asthma: a placebo-controlled study. Am J Respir Crit Care Med 1997;155:1864-71.
33. Laitinen A, Altraja A, Kampe M, Linden M, Virtanen I, Laitinen LA. Tenascin is increased in airway basement membrane of asthmatics and decreased by an inhaled steroid. Am J Respir Crit Care Med 1997;156:951-8.