The RXR homolog ultraspiracle is an essential component of the Drosophila ecdysone receptor

Development

Volumn 125, Issue 23, 1998, Pages 4709-4717

  Hall, Bonnie L ^a   Thummel, Carl S ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Drosophila; Ecdysone receptor; Gene regulation; Juvenile hormone; Metamorphosis; Nuclear receptor; RXR; Ultraspiracle

Indexed keywords

ECDYSONE; HORMONE RECEPTOR; RETINOID X RECEPTOR; STEROID RECEPTOR;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; DROSOPHILA; EMBRYO; GENE LOCUS; IMAGINAL DISC; LARVAL DEVELOPMENT; METAMORPHOSIS; MIDGUT; MOLTING; NONHUMAN; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; SALIVARY GLAND;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; DIGESTIVE SYSTEM; DIMERIZATION; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; LARVA; METAMORPHOSIS, BIOLOGICAL; RECEPTORS, RETINOIC ACID; RECEPTORS, STEROID; RETINOID X RECEPTORS; SALIVARY GLANDS; TRANSCRIPTION FACTORS;

ANIMALIA; HEXAPODA; INSECTA;

EID: 0032428044     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Andres, A. J., Fletcher, J. C., Karim, F. D. and Thummel, C. S. (1993). Molecular analysis of the initiation of insect metamorphosis: A comparative study of Drosophila ecdysteroid-regulated transcription. Dev. Biol. 160, 388-404.
2. Andres, A. J. and Thummel, C. S. (1994). Methods for quantitative analysis of transcription in larvae and prepupae. In Drosophila melanogaster: Practical Uses in Cell and Molecular Biology (ed. L. S. B. Goldstein and E. A. Fyrberg) pp. 565-573. New York: Academic Press.
3. Antoniewski, C., Mugat, B., Delbac, F. and Lepesant, J.-A. (1996). Direct repeats bind the EcR/USP receptor and mediate ecdysteroid responses in Drosophila melanogaster. Mol. Cell. Biol. 16, 2977-2986.
4. Appel, L. F., Prout, M., Abu-Shuniays, R., Hammonds, A., Garbe, J. C., Fristrom, D. and Fristrom, J. (1993). The Drosophila Stubble-stubbloid gene encodes an apparent transmembrane serine protease required for epithelial morphogenesis. Proc. Natl. Acad. Sci. USA 90, 4937-4941.
5. Apple, R. T. and Fristrom, J. W. (1991). 20-hydroxyecdysone is required for, and negatively regulates, transcription of Drosophila pupal cuticle protein genes. Der. Biol 146, 569-582.
6. Ashburner, M., Chihara, C., Meltzer, P. and Richards, G. (1974). Temporal control of puffing activity in polytene chromosomes. Cold Spring Harbor Symp. Quant. Biol. 38, 655-662.
7. Becker, H. J. (1959). Die puffs der speicheldrüsenchromosomen von Drosophila melanogaster. I. Beobachtungen zur verhalten des puffmusters in normalstamm und bei zwei mutanten, giant und lethal-giant-larvae. Chromosoma 10, 654-678.
8. Bender, M., Imam, F. B., Talbot, W. S., Ganetzky, B. and Hogness, D. S. (1997). Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Cell 91, 777-788.
9. ls, a temperature-sensitive mutant of Drosophila melanogaster. Gen. Comp. Endocrin. 54, 76-84.
10. Bodenstein, D. (1965). The postembryonic development of Drosophila. In Biology of Drosophila (ed. M. Demerec) pp. 275-367. New York: Hafner Publishing Co.
11. Burlis, K. C., Thummel, C. S., Jones, C. W., Karim, F. D. and Hogness, D. S. (1990). The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins. Cell 61, 85-99.
12. Charles, J.-P., Chihara, C., Nejad, S. and Riddiford, L. M. (1997). A cluster of cuticle protein genes of Drosophila melanogaster at 65A: Sequence, structure and evolution. Genetics 147, 1213-1224.
13. Charles, J.-P., Chihara, C., Nejad, S. and Riddiford, L. M. (1998). Identification of proteins and developmental expression of RNAs encoded by the 65A cuticle protein gene cluster in Drosophila melanogaster. Insect Biochem. Mol. Biol. 28, 131-138.
14. Clever, U. and Karlson, P. (1960). Induktion von puff-veränderungen in den speicheldrüsenchromosomen von Chironomus tentans durch ecdyson. Exp. Cell. Res. 20, 623-626.
15. Crossgrove, K., Bayer, C. A., Fristrom, J. W. and Guild, G. M. (1996). The Drosophila Broad-Complex early gene directly regulates late gene transcription during the ecdysone-induced puffing cascade. Dev. Biol. 180, 745-758.
16. D'Avino, P. P., Crispi, S., Cherbas, L., Cherbas, P. and Furia, M. (1995a). The moulting hormone ecdysone is able to recognize target elements composed of direct repeats. Mol. Cell. Endo. 113, 1-9.
17. D'Avino, P. P., Crispi, S., Polito, L. C. and Furia, M. (1995b). The role of the BR-C locus on the expression of genes located at the ecdysone-regulated 3C puff of Drosophila melanogaster. Mech. Dev. 49, 161-171.
18. DiBello, P. R., Withers, D. A., Bayer, C. A., Fristrom, J. W. and Guild, G. M. (1991). The Drosophila Broad-Complex encodes a family of related proteins containing zinc fingers. Genetics 129, 385-397.
19. Dominick, O. S. and Truman, J. W. (1985). The physiology of wandering behavior in Manduca sexta. II. The endocrine control of wandering behavior. J. Exp. Biol. 117, 45-68.
20. Fechtel, K., Natzle, J. E., Brown, E. E. and Fristrom, J. W. (1988). Prepupal differentiation of Drosophila imaginal discs: identification of four genes whose transcripts accumulate in response to a pulse of 20-hydroxyecdysone. Genetics 120, 465-474.
21. Fisk, G. J. and Thummel, C. S. (1998). The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosis. Cell 93, 543-555.
22. Fletcher, J. C., Burtis, K. C., Hogness, D. S. and Thummel, C. S. (1995). The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone. Development 121, 1455-1465.