Observations on the etiology and pathogenesis of intraductal papillary-mucinous neoplasms of the pancreas

Hepato-Gastroenterology

Volumn 45, Issue 24, 1998, Pages 1973-1980

  Longnecker, Daniel S ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Intraductal papillary mucinous neoplasm; Mucinous cystic neoplasm; Mucinous duct ectasia

Indexed keywords

MUCIN;

ADENOCARCINOMA; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONFERENCE PAPER; CYSTADENOMA; HUMAN; MOLECULAR BIOLOGY; MORPHOLOGY; NONHUMAN; PANCREAS TUMOR; PANCREATOGRAPHY; PAPILLOMA; PRIORITY JOURNAL;

ADENOCARCINOMA, MUCINOUS; ADENOCARCINOMA, PAPILLARY; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; CYSTADENOCARCINOMA, MUCINOUS; CYSTADENOCARCINOMA, PAPILLARY; DIAGNOSIS, DIFFERENTIAL; HUMANS; PANCREAS; PANCREATIC DUCTS; PANCREATIC NEOPLASMS; PROGNOSIS;

EID: 0032427099     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (35)

1. Kloppel G, Solcia E, Longnecker DS, Capella C, Sobin LH: Histologic Typing of Tumours of the Exocrine Pancreas. Springer-Verlag, New York, 1996.
2. Solcia E, Capella C, Kloppel G (1997):. Atlas of Tumor Pathology: Tumors of the Pancreas. Armed Forces Institute of Pathology, Washington, DC, 1997.
3. Japan Pancreas Society: Classification of Pancreatic Carcinoma. Kanehara & Co., Ltd. Tokyo, 1996.
4. Rosai J (1996): Pancreas and periampullary region. In: Rosai J (Ed.). Ackerman's Surgical Pathology, Ch. 15. Mosby Year Book, Inc., St. Louis, 1996 pp. 969-1013.
5. Shimizu M, Manabe T: Mucin-producing pancreatic tumors: Historical review of its nosological concept. Zentralbl Pathol 1994; 140:211-223.
6. Ohashi K, Takagi K: ERCP and imaging diagnosis of pancreatic cancer. Gastroenterol Endoscopy 1980; 77:1493-1495.
7. Gibson JB, Sobin LH: Histological typing of tumours of the liver, biliary tract and pancreas. World Health Org 1978.
8. Furukawa T, Takahashi T, Kobari M, Matsuno S: The mucus-hyper-secreting tumor. Cancer 1992; 70:1505-1513.
9. Sessa F, Solcia E, Capella C, Bonato M, Scarpa A, Zamboni G, Pellegata NS, Ramzani GN, Rickaert F, Kloppel G: Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients. Virchows Arch 1994; 425:357-367.
10. Fukushima N, Muaki K, Kanai Y, Hasebe T, Shimada K, Ozaki H, Kinoshita T, Kosuge T: Intraductal papillary tumors and mucinous cystic tumors of the pancreas: clinicopathologic study of 38 cases. Human Pathol 1997; 28:1010-1017.
11. Yamada M, Kozuka S, Yamao K, Nakazawa S, Naitoh Y, Tsukamoto Y: Mucin-producing tumor of the pancreas. Cancer 1991; 68:159-168.
12. Yamao K, Nakazawa S, Fujimoto M, Yamada M, Milchgrub S, Albores-Saavedra J: Intraductal papillary mucinous tumors, non-invasive and invasive. In: Pour PM, Konishi Y, Kloppel G, Longnecker DS (Eds.) Atlas of exocrine pancreatic tumors. Springer-Verlag, Tokyo, 1994.
13. Compagno J, Oertel JE: Mucinous cystic neoplasms of the pancreas with overt and latent malignancy (cystadenocarcinoma and cystadenoma): A clinicopathologic study of 41 cases. Am J of Clinical Pathol 1978; 69:573-580.
14. Longnecker DS, Kato Y, Konishi Y, Freeman D, Glasner S, Memoli VA, Morohoshi T, Mott L, Mukai K, Ozaki H, Tsunoda T, Tsutsumi M, Kloppel G: Comparison of histologic type and stage of exocrine pancreatic neoplasms from surgical series in Europe, Japan and the United States. In: Beger HG, Buchler MW, Schoenberg MH (Eds.). Cancer of the Pancreas: Molecular Biology, Progress in Diagnosis and Treatment. Springer-Verlag, Heidelberg, 1996; pp. 47-54.
15. Freeny PC: Cross-sectional imaging of the pancreas. Balliere's Clin Gastroenterol 1995; 9:135-151.
16. Megibow AJ: Pancreatic adenocarcinoma: designing the examination to evaluate the clinical questions. Radiology 1992; 183:297-303.
17. Ratcliffe N, Terhune P, Longnecker DS: Small intraductal papillary-mucinous adenomas of the pancreas. Arch Pathol Lab Med 1996; 120:1111-1115.
18. Kloppel G: Intraductal papillary-mucinous tumor in pancreatic tumor development. Int J Pancreatol 1994; 16:201 (abstract).
19. Nagai E, Ueki T, Chijiiwa K, Tanaka M, Tsuneyoshi M: Intraductal papillary mucinous neoplasms of the pancreas associated with so-called "mucinous ductal ectasia". Histochemical and immunohistochemical analysis of 29 cases. Amer J Surg Pathol 1995; 576-589.
20. Cubilla AL, Fitzgerald PJ: Morphological lesions associated with human primary invasive nonendocrine pancreas cancer. Cancer Res 1976; 36:2690-2698.
21. Albores-Saavedra J, Vuitch F, Henson DE: Exocrine Pancreas. In: Henson DE, Albores-Saavedra (Eds.). The Pathology of Incipient Neoplasia. W.B. Saunders Co., Philadelphia, 28, 1993; pp. 182-190.
22. Longnecker DS, Kloppel G, Pour PM: Preneoplastic lesions of the exocrine pancreas. In: Pour PM, Konishi Y, Kloppel G, Longnecker DS (Eds.). Atlas of Exocrine Pancreatic Tumors. Springer-Verlag, Tokyo, 1994.
23. Terhune PG, Longnecker DS: Do oncogene and tumor suppressor gene abnormalities vary with type of carcinoma of the pancreas? J Hep Bil Pancr Surg 1995; 2:1-7.
24. Caldas C, Kern SE: K-ras mutation and pancreatic adenocarcinoma: state-of-the-art. Int J Pancreatol 1995; 18:1-6.
25. Satoh K, Sasano H, Shimosegawa T, Koizumi M, Yamazaki T, Mochizuki F, Kobayashi N, Okano T, Toyota T, Sawai T: An immunohistochemical study of the c-erbB-2 oncogene product in intraductal mucinhypersecreting neoplasms and in ductal cell carcinomas of the pancreas. Cancer 1993; 72:51-56.
26. Terada T, Ohta T, Nakanuma Y: Expression of oncogene products, anti-oncogene products and oncofetal antigens in intraductal papillary-mucinous neoplasm of the pancreas. Histopathology 1996; 29:355-361.
27. Satoh K, Ohtani H, Shimosegawa T, Koizumi M, Sawai T, Toyota T: Infrequent stromal expression of gelatinase A and intact basement membrane in intraductal neoplasms of the pancreas. Gastroenterol 1994; 107:1488-1495.
28. Terada T, Nakanuma Y: Expression of mucin carbohydrate antigens (T, Tn and sialyl Tn) and MUC-1 gene product in intraductal papillary-mucinous neoplasm of the pancreas. Am J Clin Pathol 1996; 105:613-620.
29. Terada T, Ohta T, Sasaki M, Nakanuma Y, Kim YS: Expression of MUC apomucins in normal pancreas and pancreatic tumours. J Pathol 1996; 180:160-165.
30. Kokkinakis DM, Albores-Saavedra J: Orotic acid enhancement of preneoplastic and neoplastic lesions induced in the pancreas and liver of hamsters by N-nitroso(2-hydroxypropyl) (2-oxopropyl)amine. Cancer Res 1994; 54:5324-5332.
31. Sugio K, Gazdar AF, Albores-Saavedra J, Kokkinakis DM: High yields of K-ras mutations in intraductal papillary mucinous tumors and invasive adenocarcinomas induced by N-nitroso(2-hydroxypropyl) (2-oxopropyl)amine in the pancreas of female Syrian hamsters. Carcinogenesis 1996; 17:303-309.
32. Schuller HM, Jorquera R, Reichert A, Castonguay A: Transplacental induction of pancreas tumors in hamsters by ethanol and the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res 1993; 53:2498-2501.
33. Rivenson A, Hoffmann D, Prokopczyk B, Amin S, Hecht SS: Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines. Cancer Res 1988; 48:1912-1917.
34. Longnecker DS, Terhune PG: Carcinogenesis and pathology of carcinomas in the pancreas: comparison with the biliary tract. In: Sirica AE, Longnecker DS (Eds.). Biliary and Pancreatic Ductal Epithelia: Pathobiology and Pathophysiology. Marcel Dekker, New York, 1997; pp. 527-562.
35. Nishihara K, Fukuda T, Tsuneyoshi M, Kominami T, Maeda S, Saku M: Intraductal papillary neoplasm of the pancreas. Cancer 1993; 72:689-696.