Unreliability of IgE/IgG4 antibody testing as a diagnostic tool in food intolerance

Clinical and Experimental Allergy

Volumn 28, Issue 12, 1998, Pages 1526-1529

  Jenkins, M ^a   Vickers, A ^a,b  

^a UCL Hospitals NHS Trust   (United Kingdom)

^b Res Cncl for Complementary Med   (United Kingdom)

Author keywords

Food intolerance; Reproducibility of results; Unconventional diagnostic tests

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4;

ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; DIAGNOSTIC TEST; FOOD ALLERGY; HUMAN; NUTRITIONAL INTOLERANCE; PRIORITY JOURNAL; RELIABILITY;

ALLERGENS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EVALUATION STUDIES; FOOD; FOOD HYPERSENSITIVITY; HUMANS; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; REPRODUCIBILITY OF RESULTS;

EID: 0032426622     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1998.00367.x     Document Type: Article

References (11)

1. Brostoff J, Challacombe SJ, (eds). Food allergy and intolerance. Eastbourne: Baillière Tindall (1987).
2. Sampson HA. Differential diagnosis in adverse reactions to food. J All Clin Immunol 1986; 78:165-74.
3. Darlington LG, Ramsey NW, Mansfield JR. Placebo-controlled, blind study of dietary manipulation therapy in rheumatoid arthritis. Lancet 1986; 1:236-8.
4. Egger J, Stolla A, McEwen LM. Controlled trial of hyposensitisation in children with food-induced hyperkinetic syndrome. Lancet 1992; 339:1150-3.
5. Shakib F, McLaughan P, Stanworth DR. Elevated serum IgE and IgG4 in patients with atopic dermatitis. Br J Dermatol 1977; 97:59-63.
6. El Rafei A, Peters SM, Harris N, Bellanti JA. Diagnostic value of IgG4 measurements in patients with food allergy. Ann All 1989; 62:94-9.
7. Sackett DL, Haynes RB, Guyatt GH, Tugwell P. Clinical Epidemiology. Boston: Little, Brown and Company (1991).
8. Roger A, Pena M, Botey J, Eseverri JL, Marin A. The value of IgG4 determination in childhood allergy to egg in relation to specific IgE and the provocation test. J Invest Allergol Clin Immunol 1994; 4:87-90.
9. Duchen K, Einarson R, Grodzinsky E, Hattevig G, Bjorksten B. Development of IgG1 and IgG4 antibodies against beta-lactoglobulin and ovalbumin in healthy and atopic children. Ann Allergy Asthma Immunol 1997; 78:363-8.
10. Kjeldsen Kragh J, Hvatum M, Haugen M, Forre O, Scott H. Antibodies against dietary antigens in rheumatoid arthritis patients treated with fasting and a one-year vegetarian diet. Clin Exp Rheumatol 1995; 13:167-72.
11. Merrett J, Peatfield RC, Rose FC, Merrett TG. Food related antibodies in headache patients. J Neurol Neurosurg Psych 1983; 46:738-42.