Structure-activity relationships for nicotine analogs comparing competition for [3H]nicotine binding and psychotropic potency

Drug Development Research

Volumn 45, Issue 1, 1998, Pages 10-16

  Wang, David X ^a   Booth, Heather ^a   Lerner Marmarosh, Nicole ^a   Osdene, Thomas S ^a   Abood, Leo G ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

4 2 receptor; 3H nicotine binding; Nicotine analogs; Prostration; Rat brain; Structure activity relationships

Indexed keywords

NICOTINE DERIVATIVE; NICOTINIC ACID METHYL ESTER; NICOTINIC AGENT; NICOTINIC RECEPTOR; PSYCHOTROPIC AGENT; PYRIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; DRUG POTENCY; DRUG RECEPTOR BINDING; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; TORPEDO;

EID: 0032425597     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2299(199809)45:1<10::AID-DDR2>3.0.CO;2-G     Document Type: Article

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