-
1
-
-
85025352713
-
Rapamycins: Antifungal, antitumor, antiproliferative, and immunosuppressive macrolides
-
R. E. Morris. Rapamycins: antifungal, antitumor, antiproliferative, and immunosuppressive macrolides. Transplant. Rev. 6:39-87 (1992).
-
(1992)
Transplant. Rev.
, vol.6
, pp. 39-87
-
-
Morris, R.E.1
-
2
-
-
0025228926
-
Cyclosporine, FK506, and rapamycin: Some effects on early activation events in serum-free, mitogen-stimulated mouse spleen cells
-
S. M. Metclafe and F. M. Richards. Cyclosporine, FK506, and rapamycin: some effects on early activation events in serum-free, mitogen-stimulated mouse spleen cells. Transplantation 49:798-803 (1990).
-
(1990)
Transplantation
, vol.49
, pp. 798-803
-
-
Metclafe, S.M.1
Richards, F.M.2
-
4
-
-
0031851786
-
Species and gender-related differences incyclosporine/prednisolone/sirolimus interaction in whole blood lymphocyte proliferation assays
-
G. M. Ferron and W. J. Jusko. Species and gender-related differences incyclosporine/prednisolone/sirolimus interaction in whole blood lymphocyte proliferation assays. J. Pharmacol. Exp. Ther. 286:191-200 (1998).
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.286
, pp. 191-200
-
-
Ferron, G.M.1
Jusko, W.J.2
-
5
-
-
0027365895
-
Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics
-
K. H. Lew, E. A. Ludwig, M. A. Milad, K. Donovan, E. Middleton, J. J. Ferry, and W. J. Jusko. Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics. Clin. Pharmacol. Ther 54:402-414 (1993).
-
(1993)
Clin. Pharmacol. Ther
, vol.54
, pp. 402-414
-
-
Lew, K.H.1
Ludwig, E.A.2
Milad, M.A.3
Donovan, K.4
Middleton, E.5
Ferry, J.J.6
Jusko, W.J.7
-
6
-
-
0030477754
-
Pharmacokinetics of prednisolone during administration of sirolimus in patients with renal transplants
-
W. J. Jusko, G. M. Ferron, S. M. Mis, B. D. Kahan, and J. J. Zimmerman. Pharmacokinetics of prednisolone during administration of sirolimus in patients with renal transplants. J. Clin. Pharmacol. 36:1100-1106 (1996).
-
(1996)
J. Clin. Pharmacol.
, vol.36
, pp. 1100-1106
-
-
Jusko, W.J.1
Ferron, G.M.2
Mis, S.M.3
Kahan, B.D.4
Zimmerman, J.J.5
-
7
-
-
0026662551
-
Cytochrome P450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat
-
M. Sattler, P. Guengerich, C.-H. Yun, U. Christians, and K.-F. Sewing. Cytochrome P450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. Drug Metab. Dispos. 20:753-761 (1992).
-
(1992)
Drug Metab. Dispos.
, vol.20
, pp. 753-761
-
-
Sattler, M.1
Guengerich, P.2
Yun, C.-H.3
Christians, U.4
Sewing, K.-F.5
-
8
-
-
0020631366
-
Urinary 6β-hydroxyprednisolone excretion indicates enhanced prednisolone catabolism
-
F. J. Frey and B. M. Frey. Urinary 6β-hydroxyprednisolone excretion indicates enhanced prednisolone catabolism. J. Lab. Clin. Med. 101:593-604 (1983).
-
(1983)
J. Lab. Clin. Med.
, vol.101
, pp. 593-604
-
-
Frey, F.J.1
Frey, B.M.2
-
9
-
-
0026280159
-
Effects of FK506 on human hepatic microsomal cytochrome P-450-dependent drug metabolism in vitro
-
I. A. Shah, P. H. Whiting, G. Omar, A. W. Thomson, and M. D. Burke. Effects of FK506 on human hepatic microsomal cytochrome P-450-dependent drug metabolism in vitro. Transplant. Proc. 23:2783-2785 (1991).
-
(1991)
Transplant. Proc.
, vol.23
, pp. 2783-2785
-
-
Shah, I.A.1
Whiting, P.H.2
Omar, G.3
Thomson, A.W.4
Burke, M.D.5
-
10
-
-
0019129243
-
Serum protein binding of prednisolone in four species
-
M. L. Rocci, N. F. Johnson, and W. J. Jusko. Serum protein binding of prednisolone in four species. J. Pharm. Sci. 69:977-978 (1980).
-
(1980)
J. Pharm. Sci.
, vol.69
, pp. 977-978
-
-
Rocci, M.L.1
Johnson, N.F.2
Jusko, W.J.3
-
11
-
-
0027328697
-
Disposition of tacrolimus (FK506) in rabbits: Role of red blood cell binding in hepatic clearance
-
W. Piekoszewski, F. S. Chow, and W. J. Jusko. Disposition of tacrolimus (FK506) in rabbits: role of red blood cell binding in hepatic clearance. Drug Metab. Dispos. 21:690-698 (1993).
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 690-698
-
-
Piekoszewski, W.1
Chow, F.S.2
Jusko, W.J.3
-
12
-
-
0031941036
-
Species differences in sirolimus stability in humans, rabbits and rats
-
G. M. Ferron and W. J. Jusko. Species differences in sirolimus stability in humans, rabbits and rats. Drug Metab. Dispos. 26:83-84 (1998).
-
(1998)
Drug Metab. Dispos.
, vol.26
, pp. 83-84
-
-
Ferron, G.M.1
Jusko, W.J.2
-
13
-
-
0028033164
-
Prednisolone pharmacodynamics: Leukocyte trafficking in the rat
-
J. A. Wald and W. J. Jusko. Prednisolone pharmacodynamics: leukocyte trafficking in the rat. Life Sci. 55:371-378 (1994).
-
(1994)
Life Sci.
, vol.55
, pp. 371-378
-
-
Wald, J.A.1
Jusko, W.J.2
-
14
-
-
0028296673
-
Pharmacokinetic and pharmacodynamic effects of coadministration of methylprednisolone and tacrolimus in rabbits
-
W. Piekoszewski, F. S. Chow, and W. J. Jusko. Pharmacokinetic and pharmacodynamic effects of coadministration of methylprednisolone and tacrolimus in rabbits. J. Pharmacol. Exp. Ther. 269:103-109 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 103-109
-
-
Piekoszewski, W.1
Chow, F.S.2
Jusko, W.J.3
-
15
-
-
0027930643
-
Fifteen years of operation of high-performance liquid chromatograpic assay for prednisolone, cortisol and prednisone in plasma
-
W. J. Jusko, N. A. Pyszczynski, M. S. Bushway, R. D'Ambrosio, and S. M. Mis. Fifteen years of operation of high-performance liquid chromatograpic assay for prednisolone, cortisol and prednisone in plasma. J. Chromatogr. B. 658:47-54 (1994).
-
(1994)
J. Chromatogr. B.
, vol.658
, pp. 47-54
-
-
Jusko, W.J.1
Pyszczynski, N.A.2
Bushway, M.S.3
D'Ambrosio, R.4
Mis, S.M.5
-
16
-
-
0031449939
-
Lipophilic benzamide and anilide derivatives as high-performance liquid chromatography internal standards: Application to sirolimus (rapamycin) determination
-
G. M. Ferron, W. D. Conway, and W. J. Jusko. Lipophilic benzamide and anilide derivatives as high-performance liquid chromatography internal standards: application to sirolimus (rapamycin) determination. J. Chromatogr. B. 703:243-251 (1997).
-
(1997)
J. Chromatogr. B.
, vol.703
, pp. 243-251
-
-
Ferron, G.M.1
Conway, W.D.2
Jusko, W.J.3
-
17
-
-
0017084256
-
Combination chemotherapy in vitro with adriamycin. Observation of additive, antagonistic, and synergistic effects when used in two-drug combinations on cultured human lymphoma cells
-
B. Drewinko, T. L. Loo, B. Brown, J. A. Gottlieb, and E. J. Freireich. Combination chemotherapy in vitro with adriamycin. Observation of additive, antagonistic, and synergistic effects when used in two-drug combinations on cultured human lymphoma cells. Can. Biochem. Biophys. 1:187-195 (1976).
-
(1976)
Can. Biochem. Biophys.
, vol.1
, pp. 187-195
-
-
Drewinko, B.1
Loo, T.L.2
Brown, B.3
Gottlieb, J.A.4
Freireich, E.J.5
-
18
-
-
0025113618
-
Application of a new approach for the quantitation of drug synergism to the combination of cisdiamminedichloroplatinium and 1-beta-D-arabinofuranosylcytosine
-
W. R. Greco, H. S. Park, and Y. M. Rustum. Application of a new approach for the quantitation of drug synergism to the combination of cisdiamminedichloroplatinium and 1-beta-D-arabinofuranosylcytosine. Cancer Res. 50:5318-5327 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 5318-5327
-
-
Greco, W.R.1
Park, H.S.2
Rustum, Y.M.3
-
19
-
-
0020963903
-
Physiologically based pharmacokinetic modeling: Principles and applications
-
L. E. Gerlowski and R. K. Jain. Physiologically based pharmacokinetic modeling: principles and applications. J. Pharm. Sci. 72:1103-1127 (1983).
-
(1983)
J. Pharm. Sci.
, vol.72
, pp. 1103-1127
-
-
Gerlowski, L.E.1
Jain, R.K.2
-
20
-
-
0021723695
-
Pharmacokinetics and pharmacodynamics of three different prednisolone prodrugs: Effect on circulating lymphocyte subsets and function
-
B. C. Frey, W. F. J. Frey, and A. L. de Weck. Pharmacokinetics and pharmacodynamics of three different prednisolone prodrugs: effect on circulating lymphocyte subsets and function. J. Immunol. 133:2479-2487 (1984).
-
(1984)
J. Immunol.
, vol.133
, pp. 2479-2487
-
-
Frey, B.C.1
Frey, W.F.J.2
De Weck, A.L.3
-
23
-
-
0030984839
-
Effect of hematocrit and albumin concentration on hepatic clearance of tacrolimus (FK506) during rabbit liver perfusion
-
F. S. Chow, W. Piekoszewski, and W. J. Jusko. Effect of hematocrit and albumin concentration on hepatic clearance of tacrolimus (FK506) during rabbit liver perfusion. Drug Metab. Dispos. 25:610-616 (1997).
-
(1997)
Drug Metab. Dispos.
, vol.25
, pp. 610-616
-
-
Chow, F.S.1
Piekoszewski, W.2
Jusko, W.J.3
-
24
-
-
0028886999
-
Rapamycin: Distribution, pharmacokinetics and therapeutic range investigations
-
R. W. Yatscoff, P. Wang, K. Chan, D. Hicks, and J. Zimmerman. Rapamycin: distribution, pharmacokinetics and therapeutic range investigations. Ther. Drug Monit. 17:666-671 (1995).
-
(1995)
Ther. Drug Monit.
, vol.17
, pp. 666-671
-
-
Yatscoff, R.W.1
Wang, P.2
Chan, K.3
Hicks, D.4
Zimmerman, J.5
-
25
-
-
0028675348
-
Pharmacodynamic model for joint exogenous and endogenous corticosteroid suppression of lymphocyte traficking
-
M. A. Milad, E. A. Ludwig, S. Anne, E. Middleton, and W. J. Jusko. Pharmacodynamic model for joint exogenous and endogenous corticosteroid suppression of lymphocyte traficking. J. Pharmacokinet. Biopharm. 22:469-480 (1994).
-
(1994)
J. Pharmacokinet. Biopharm.
, vol.22
, pp. 469-480
-
-
Milad, M.A.1
Ludwig, E.A.2
Anne, S.3
Middleton, E.4
Jusko, W.J.5
-
26
-
-
2542509071
-
Immunophilins, heat shock proteins, and glucocorticoid receptor actions in vivo
-
Y. M. Ning and E. R. Sanchez. Immunophilins, heat shock proteins, and glucocorticoid receptor actions in vivo. Methods 9:188-200 (1996).
-
(1996)
Methods
, vol.9
, pp. 188-200
-
-
Ning, Y.M.1
Sanchez, E.R.2
-
27
-
-
0029820263
-
Immunopharmacologic therapy in renal transplantation
-
A. S. Shoker. Immunopharmacologic therapy in renal transplantation. Pharmacotherapy 16:562-575 (1996).
-
(1996)
Pharmacotherapy
, vol.16
, pp. 562-575
-
-
Shoker, A.S.1
-
28
-
-
0028258845
-
Trends in the use of glucocorticoids in renal transplantation
-
D. E. Hricik, W. Y. Almawi, and T. B. Strom. Trends in the use of glucocorticoids in renal transplantation. Transplantation 57:979-989 (1994).
-
(1994)
Transplantation
, vol.57
, pp. 979-989
-
-
Hricik, D.E.1
Almawi, W.Y.2
Strom, T.B.3
-
29
-
-
0030064388
-
The side effect profile of sirolimus: A phase I study in quiescent cyclosporin-prednisone treated renal transplant patients
-
M. G. Murgia, S. Jordan, and B. D. Kahan. The side effect profile of sirolimus: a phase I study in quiescent cyclosporin-prednisone treated renal transplant patients. Kidney Int. 49:209-216 (1996).
-
(1996)
Kidney Int.
, vol.49
, pp. 209-216
-
-
Murgia, M.G.1
Jordan, S.2
Kahan, B.D.3
|