Identification of a locus on chromosome 7q31, DFNB14, responsible for prelingual sensorineural non-syndromic deafness

European Journal of Human Genetics

Volumn 6, Issue 6, 1998, Pages 548-551

  Mustapha, Mirna ^a,b   Salem, Nabiha ^a   Weil, Dominique ^b   El Zir, Elie ^c   Loiselet, Jacques ^a   Petit, Christine ^b,d  

^a SAINT JOSEPH UNIVERSITY   (Lebanon)

^b INSTITUT PASTEUR   (France)

^c Sacre Coeur Hospital Baabda   (Lebanon)

^d CNRS   (France)

Author keywords

Homozygosity mapping; Middle East population; Non syndromic recessive sensorineural hearing loss

Indexed keywords

DNA MARKER;

ADULT; ARTICLE; CHILD; CHROMOSOME 7Q; CONSANGUINITY; FEMALE; GENE LOCUS; GENETIC LINKAGE; HUMAN; MALE; PENDRED SYNDROME; PERCEPTION DEAFNESS; PRIORITY JOURNAL; SEGREGATION ANALYSIS;

EID: 0032423008     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200261     Document Type: Article

References (18)

1. Petit C: Genes responsible for human hereditary deafness: symphony of a thousand. Nat Genet 1996; 14: 385-391.
2. Van Camp G, Smith RJH: http://dnalab-www.uia.ac.be/ dnalab/hhh. Hereditary Hearing Loss Homepage 1998.
3. Kelsell DP, Dunlop J, Stevens HP et al Connexin 26 mutations in hereditary non-syndromic sensorineural deafness. Nature 1997; 387: 80-83.
4. Liu X-Z, Walsh J, Mburu P et al: Mutations in the myosin VIIA gene cause non-syndromic recessive deafness. Nat Genet 1997; 16: 188-190.
5. Weil D, Küssel P, Blanchard S et al: The autosomal recessive isolated deafness, DFNB2, and the Usher IB syndrome are allelic defects of the myosin-VIIA gene. Nat Genet 1997; 16: 191-193.
6. Wang A, Liang Y, Fridell RA et al: Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3. Science 1998; 280: 1447-1451.
7. Li XC, Everett LA, Lalwani AK et al: A mutation in PDS causes non-syndromic recessive deafness. Nat Genet 1998; 18: 215-217.
8. Baldwin CT, Weiss S, Farrer LA et al: Linkage of congenital, recessive deafness (DFNB4) to chromosome 7q31 and evidence for genetic heterogeneity in the Middle Eastern Druze population. Hum Mol Genet 1995; 4: 1637-1642.
9. Der Kaloustian VM, Naffah J, Loiselet J: Genetic diseases in Lebanon. Am J Med Genet 1980; 7: 187-203.
10. Chaïb H, Place C, Salem N et al: A gene responsible for a sensorineural nonsyndromic recessive deafness maps to chromosome 2p22-23. Hum Mol Genet 1996; 5: 155-158.
11. Chaïb H, Place C, Salem N et al: Mapping of DFNB12, a gene for a non-syndromic autosomal recessive deafness, to chromosome 10q21-22. Hum Mol Genet 1996; 5: 1061-1064.
12. Mustapha M, Chardenoux S, Nieder A et al: A sensorineural progressive autosomal recessive form of isolated deafness, DFNB13, maps to chromosome 7q34-q36. Eur J Hum Genet 1998; 6: 245-250.
13. Van Hauwe P, Everett LA, Coucke P et al: Two frequent missense mutations in Pendred syndrome. Hum Mol Genet 1998; 7: 1099-1104.
14. Coyle B, Reardon W, Herbrick J-A et al: Molecular analysis of the PDS gene in Pendred syndrome (sensorineural hearing loss and goitre). Hum Mol Genet 1998; 7: 1105-1112.
15. Everett LA, Glaser B, Beck JC et al: Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS). Nat Genet 1997; 17: 411-422.
16. Macalma T, Otte J, Hensler ME et al: Molecular characterization of human zyxin. J Biol Chem 1996; 271: 31470-31478.
17. Dib C, Fauré S, Fizames C et al: A comprehensive genetic map of the human genome based on 5264 microsatellites. Nature 1996; 380: 152-154.
18. Kruglyak L, Daly MJ, Lander ES: Rapid multipoint linkage analysis of recessive traits in nuclear families, including homozygosity mapping. Am J Hum Genet 1995; 56: 519-527.