Timing of low-level NO2 exposure alters antigen-specific IgE, IgG, and IgG(2a) antibody production in mice

Inhalation Toxicology

Volumn 10, Issue 12, 1998, Pages 1079-1093

  Fujimaki, Hidekazu ^a   Ohmori, Takechika ^b   Ushio, Hiroko ^a   Saneyoshi, Kensaku ^b  

^a NATIONAL INSTITUTE FOR ENVIRONMENTAL STUDIES   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032422436     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/089583798197295     Document Type: Article

References (23)

1. Baraniuk, J. N. 1997. Pathogenesis of allergic rhinitis. J. Allergy Clin. Immunol. 99:S763-S772.
2. Chitano, P., Hosselet, J. J., Mapp, C. E., and Fabbri, L. M. 1995. Effect of oxidant air pollutants on the respiratory system: Insights from experimental animal research, Eur. Respir. J. 8:1357-1371.
3. 2 reduces TNF and IL-6 production by endotoxin-stimulated alveolar macrophages. Am. J. Physiol. 271:E132-E138.
4. 2 on lymphocytes required for antibody responses. Environ. Res. 29:280-286.
5. Gilmour, M. I. 1995. Interaction of air pollutants and pulmonary allergic responses in experimental animals. Toxicology 105:335-342.
6. 2. Fundam. Appl. Toxicol. 31:65-70.
7. Holt, P. G., Oliver, J., Bilyk, N., McMenamin, C., McMenamin, P. G., Kraal, G., and Thepen, T. 1993. Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages. J. Exp. Med. 177:397-407.
8. Imai, T., Shimizu, F., Fujimaki, H., and Watanabe, N. 1983. Enhancement of IgE antibody production by ovalbumin aerosol in mice. Int. Arch. Allergy Appl. Immunol. 70:368-372.
9. Infante-Rivard, C. 1993. Childhood asthma and indoor environmental risk factors. Am. J. Epidemiol. 137:834-844.
10. 2 exposure. Lung 174:57-67.
11. Kobayashi, T., and Miura, T. 1995. Concentration- and time-dependent increase in specific airway resistance after induction of airway hyperresponsiveness by subchronic exposure of guinea pigs to nitrogen dioxide. Fundam. Appl. Toxicol. 25:154-158.
12. Koren, S. 1995. Associations between criteria air pollutants and asthma. Environ. Health Perspect. 103(suppl. 6):235-242.
13. 2 on immune responses. J. Toxicol. Environ. Health 17:241-248.
14. Leikauf, G. D., Kline, S., Albert, R. E., Stuart Baxter, C., Bernstein, D. I., Bernstein, J., and Buncher, C. R. 1995. Evaluation of a possible association of urban air toxics and asthma. Environ. Health Perspect. 103:253-271.
15. Mohsenin, V. 1987. Airway responses to nitrogen dioxide in asthmatic subjects. J. Toxicol. Environ. Health 22:371-380.
16. Palmer, E. M., and van Seventer, G. A. 1997. Human T helper cell differentiation is regulated by the combined action of cytokines and accessory cell-dependent costimulatory signals. J. Immunol. 158:2654-2662.
17. 2. J. Toxicol. Environ. Health 38:273-292.
18. Sedgwick, J. D., and Holt, P. G. 1985. Down-regulation of immune responses to inhaled antigen: Studies on the mechanism of induced suppression. Immunology 56:635-642.
19. Snapper, C. M., and Mond, J. J. 1993. Towards a comprehensive view of immunoglobulin class switching. Immunol. Today 14:15-17.
20. Strand, V., Salomonsson, P., Lundahl, J., and Bylin, G. 1995. Immediate and delayed effects of nitrogen dioxide exposure at an ambient level on bronchial responsiveness to histamine in subjects with asthma. Eur. Respir. J. 9:733-740.
21. Strand, V., Rak, S., Svartengren, M., and Bylin, G. 1997. Nitrogen dioxide exposure enhances asthmatic reaction to inhaled allergen in subjects with asthma. Am. J. Respir. Crit. Care Med. 155: 881-887.
22. Van Loveren, H., Rombout, P. J. A., Fischer, P. H., Lebret, E., and Van Bree, L. 1995. Modulation of host defenses by exposure to oxidant air pollutants. Inhal. Toxicol. 7:405-423.
23. Watanabe, N., and Ovary, Z. 1977. Antigen and antibody detection by in vivo methods. A reevaluation of passive cutaneous anaphylactic reactions. J. Immunol. Methods 14:382-390.