Rhenium-188 - A generator-derived radioisotope for cancer therapy

Cancer Biotherapy and Radiopharmaceuticals

Volumn 13, Issue 5, 1998, Pages 337-349

  Knapp Jr , F F ^a  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEXIDRONAM SAMARIUM SM 153; RADIOISOTOPE; RHENIUM 186; RHENIUM 188; STRONTIUM 89; TUNGSTEN 188; UNCLASSIFIED DRUG;

ARTICLE; BONE PAIN; CANCER; CANCER PALLIATIVE THERAPY; CANCER THERAPY; DRUG COST; DRUG HALF LIFE; PRIORITY JOURNAL; RADIATION DOSE; RADIOACTIVITY;

EID: 0032421713     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.1998.13.337     Document Type: Article

References (10)

1. Knapp FF Jr, Beets AL, Guhlke S, Zamora PO, Bender H, Palmedo H, Biersack, H.-J. Availability of rhenium-188 from the alumina-based tungsten-188/rhenium-188 generator for preparation of rhenium-188-labeled radiopharmaceuticals for cancer treatment. Anticancer Research 1997;17:1783.
2. Knapp FF JR, Mirzahdeh S, Beets AL, Sharkey R, Griffiths G, Juweid M, Goldenberg DM. Curie-scale tungsten-188/rhenium generators for routine clinical applications, in (M. Nicolini, B. Bandoli, U. Mazzi, eds.) Technetium Chemistry and Nuclear Medicine 4, Padova, SGEditoriali, pp., 319-324, 1995.
3. Knapp FF Jr, Beets AL, Mirzadeh S, Guhlke S. Use of a new tandem cation/anion exchange system with clinical-scale generators provides high specific volume solutions of technetium-99m and rhenium-188. In, Proceedings, Symposium on International Trends in Radiopharmaceuticals for Diagnosis and Therapy, International Atomic Energy Agency (IAEA), Lisbon, Portugal, March 30-April 2, 1998, in press.
4. Knapp FF JR, Mirzadeh S, Beets AL, Sharkey R, Griffiths G and Goldenberg DM Curie-scale tungsten-188/rhenium-188 generators can cost-effectively provide carrier-free rhenium-188 for routine clinical applications. In, Technetium and Rhenium in Nuclear Medicine, SG Editoriali, Padova, Italy, pp. 367-372, 1995.
5. Knapp FF JR, Lisic E, Mirzadeh S, Callahan AP and Rice DE. A new clinical prototype tungsten-188/rhenium-188 generator to provide high levels of carrier-free rhenium-188 for radioimmunotherapy. In, Nuclear Medicine in Research and Practice, Schattauer Verlag, Stuutgart, Germany, pp. 183-186, 1992.
6. Callahan AP, Rice DE and Knapp FF Jr. Rhenium-188 for therapeutic applications from an alumina-based tungsten-188/rhenium-188 radionuclide generator. NucCompact 1989;20:3.
7. Knapp FF Jr, Guhlke S, Weinberger J, Beets AL, Amols H, Palmedo H, Biersack HJ. High specific volume rhenium-188 - clinical potential of a readily available therapeutic radioisotope. Nuklearmedizin 1997; 36:A38.
8. Kamioki H, Mirzadeh S, Lambrecht RM, Knapp FF Jr, Dadachova E. Tungsten-188/rhenium-188 generator for biomedical applications. Radiochim Acta 1994; 65:39.
9. Knapp FF JR, Mirzadeh S, Zamora P, Guhlke S, Biersack H-J, O'Doherty MJ and Blower PJ. Rhenium-188 - cost effective therapeutic applications of a readily available generator-derived radioisotope. Nucl Med Commun 1996;17:268.
10. Knapp FF Jr, Callahan AP, Beets AL, Mirzadeh S., Hsieh BT. Processing of reactor-produced tungsten-188 for fabrication of clinical-scale alumina-based tungsten-188/rhenium-188 generators. Appl Radiat Isot 1997;45:1123.