Knockout animals in toxicology: Assessment of toxin bioactivation pathways using mice deficient in xenobiotic metabolizing enzymes

Toxicology Letters

Volumn 102-103, Issue , 1998, Pages 459-464

  Pineau, T ^a   Costet, P ^a   Puel, O ^a   Pfohl Leszkowicz, A ^b   Lesca, P ^a   Alvinerie, M ^a   Galtier, P ^a  

^a CEMAGREF   (France)

^b UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Cytochrome P450; Knockout; Metabolism; Toxicity; Xenobiotic

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CANTHAXANTHIN; CYTOCHROME P450; DIMETHYLNITROSAMINE DEMETHYLASE; MYCOTOXIN; PARACETAMOL; PHENACETIN O DEETHYLASE; POLYCYCLIC HYDROCARBON; XENOBIOTIC AGENT;

ANIMAL MODEL; BIOASSAY; CARCINOGEN TESTING; CONFERENCE PAPER; KNOCKOUT GENE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; XENOBIOTIC METABOLISM;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; MICE; MICE, KNOCKOUT; MYCOTOXINS; P-GLYCOPROTEIN; POLYCYCLIC HYDROCARBONS, AROMATIC; RECEPTORS, ARYL HYDROCARBON; TOXICOLOGY; XENOBIOTICS;

ANIMALIA; MUS MUSCULUS;

EID: 0032421134     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00339-7     Document Type: Conference Paper

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