Potentiation of muscimol-induced long-term depression by benzodiazepines and prevention or reversal by pregnenolone sulfate

Pharmacological Research

Volumn 38, Issue 6, 1998, Pages 441-448

  Akhondzadeh, S ^a   Stone, T W ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Benzodiazepines; Dementia; Long term depression; Pregnenolone sulfate

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALFAXALONE; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BICUCULLINE; CALCIUM ION; GLUTAMATE RECEPTOR; MUSCIMOL; NEUROSTEROID; PENTOBARBITAL; PREGNENOLONE SULFATE;

AMNESIA; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG POTENTIATION; EXTRACELLULAR CALCIUM; HIPPOCAMPUS; MALE; NERVE CELL INHIBITION; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

EID: 0032420898     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.1998.0388     Document Type: Article

References (50)

1. A receptor: the receptor channel superfamily. Trends Neurosci 1987; 10: 502-9.
2. B receptor subtypes. Trends Neurosci 1989; 11: 112-6.
3. A receptors. Neuropsychopharmacology 1991; 4: 225-35.
4. 4. Sivilloti L, Nistri A. GABA receptor mechanisms in the central nervous system. Prog Neurobiol 1991; 36: 35-92.
5. 5. Delory TM, Olsen RW. γ-amino butyric acid A receptor structure and function. J Biol Chem 1992; 267: 16747-50.
6. 6. Thompson SM. Modulation of inhibitory synaptic transmission in the hippocampus. Prog Neurobiol 1994; 42: 575-609.
7. 7. Magewska MD, Harrison NL, Schwartz RD, Barkre JL, Paul SM. Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor. Science NY 1988; 232: 1004-7.
8. A receptor by depressant barbiturates and pregnan steroids. Br J Pharmacol 1988; 94: 1257-69.
9. - currents. Mol Pharmacol 1991; 39: 691-6.
10. 10. Brioni JD. Role of GABA during the multiple consolidation of memory. Drug Dev Res 1993; 28: 3-27.
11. 11. Harrison NL, Simmonds MA. Modulation of GABA receptor complex by a steroid anaesthetic. Brain Res 1984; 323: 287-92.
12. 12. Turner JP, Simmonds MA. Receptor complex by steroids in slices of rat cuneate nucellus. Br J Pharmacol 1989; 96: 409-17.
13. A receptor. Harm Behav 1994; 28: 537-44.
14. 14. Akhondzadeh S, Stone TW. Potentiation by neurosteroids of muscimol/adenosine interaction in rat hippocampus. Brain Res 1995; 677: 311-18.
15. 15. Brioni JD, McGaugh JL. Post-training administration of GABAergic system in the modulation of memory storage. Brain Res 1988; 487: 105-12.
16. 16. Preston GG, Ward CE, Broks P. Effects of lorazepam on memory, attention and sedation in man: antagonism by Ro 15-1788. Psychopharmacology 1989; 97: 222-7.
17. 17. Arolfo MP, Brioni JD. Diazepam impairs place learning in the morris water maze. Behav Neural Biol 1991; 55: 131-6.
18. 18. Brioni JD, Arolfo MP. Diazepam impairs retention of spatial information without affecting retrieval or cue learning. Pharmacol Biochem Behav 1992; 41: 1-5.
19. 19. King DJ. Benzodiazepines, amnesia and sedation: theoretical and clinical issues and controversies. Human Psychopharmacol 1992; 7: 79-87.
20. 20. Thompson DM, Auta J, Guidotti A, Costa E. Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys. J Pharmacol Exp Ther 1995; 273: 1307-12.
21. 21. Del Cerro S, Jung M, Lynch G. Triazolam and diazepam block LTP in rat hippocampal and pyriform cortex slices. Soc Neurosci 1991; 17: 950.
22. 22. Levy WB, Steward O. Synapses as associative memory elements in the hippocampal formation. Brain Res 1970; 175: 233-45.
23. 23. Ito M. Long-term depression. Annu Rev Neurosci 1989; 12: 85-102.
24. 24. Dudek SM, Bear MF. Homosynaptic long-term depression in area CA1 of hippocampus and the effects of NMDA receptor blockade. Proc Natl Acad Sci USA 1992; 89: 288-93.
25. 25. Artola A, Singer W. Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation. Trends Neurosci 1993; 16: 480-7.
26. 26. Pennartz CMA, Ameerun RF, Groenewegen HJ, Lopes de silva FH. Synaptic plasticity in an in vitro slice preparation of the rat nucleus accumbens. Eur J Neurosci 1993; 5: 107-17.
27. 27. Eichenbaum H, Otto T, Cohen NJ. Two functional components of the hippocampal memory system. Behav Brain Sci 1994; 17: 449-518.
28. 28. Linden DJ. Long-term synaptic depression in the mammalian brain. Neuron 1994; 12: 457-72.
29. 29. Bear M, Abraham. W. Long-term depression in hippocampus. Annu Rev Neurosci 1996; 19: 437-62.
30. 30. Stanton PK, Sejnowski TJ. Associative long-term depression in the hippocampus induced by Hebbian covariance. Nature 1989; 339: 215-18.
31. 31. Aroniadou VA, Teyler TJ. The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex. Brain Res 1991; 562: 136-43.
32. 32. Bashir ZI, Collingridge GL. NMDA receptors-dependent transient homo-and hetrosynaptic depression in picrotoxin-treated hippocampal slices. J Neurosci 1992; 4: 485-90.
33. 2 dopamine receptors is required for long-term synaptic depression in the striatum. Neurosci Lett 1992; 142: 95-9.
34. 34. Bliss TW, Collingridge GL. A synaptic model of memory: long-term potentiation in the hippocampus. Nat Lond 1993; 361: 31-9.
35. 35. Lovinger DM, Tyler EC, Merritt AJ. Short and long-term synaptic depression in rat neostriatum. Neurophysiology 1993; 70: 1937-49.
36. 36. Christie B, Kerr DS, Abraham WC. Flip side of synaptic plasticity: long-term depression mechanisms in the hippocampus. Hippocampus 1994; 4: 127-35.
37. 37. Hirano T, Kasono K, Shigemoto R, Nakanishi S. Induction mechanism of long term depression in cultured purkinje neurons. Biomedical Res 1994; 15: 79-81.
38. 38. Staubli U, Lynch G. Stable depression of potentiated synaptic responses in the hippocampus with 1-5 Hz stimulation. Brain Res 1990; 513: 113-18.
39. 39. Braham CR, Srebro B. Induction of long-term depression and potentiation by low and high frequency stimulation in the dentate areas of the anaesthetized rat. Brain Res 1987; 405: 100-7.
40. 40. Castellano C, McGaugh JL. Effects of post-training bicuculline and muscimol on retention: lack of state dependency. Behav Neural Biol 1990; 54: 156-64.
41. 41. Mulkey RM, Malenka RC. Mechanisms underlying indication of homosynaptic long-term depression in area CA1 of the hippocampus. Nature 1992; 9: 967-75.
42. 42. Yang XD, Connor JA, Faber DS. Weak excitation and simultaneous inhibition induce long-term depression in hippocampal CA1 neurons. J Neurophysiol 1994; 71: 1586-90.
43. A but not glutamate receptors. Br J Pharmacol 1995; 115: 527-33.
44. 44. Akhondzadeh S, Stone TW. Muscimol-induced long-term depression in the hippocampus: lack of dependence on extracellular calcium. Neuroscience 1996; 71: 581-8.
45. 45. Akhondzadeh S, Stone TW. Maintenance of muscimol induced long-term depression by neurosteroids. Prog Neuro-Psychopharmacol Biol Psychiatry 1996; 20: 277-89.
46. A receptors. Life Sci 1996; 58:1023-30.
47. 47. Majewska MD, Bluet-Pajot M, Robel O, Baulieu E. Pregnenolone sulfate antagonizes barbiturate-like modulators of the GABA receptor. Science 1989; 232: 1004-7.
48. 48. Breen RA, McGaugh JL. Facilitation of maze learning with post-trial injections of picrotoxin. J Comp Physiol Psychol 1961; 54: 498-501.
49. A receptor. Brain Res 1990; 526: 143-6.
50. 50. Chenery DL, Uzunov D, Guidotti A. Pregnenolone sulfate antagonizes dizocilipine amnesia: role for allopregnanolone. Neuroreport 1995; 6: 1697-1700.