Determination of 13-cis-3-hydroxyretinoic acid, all-trans-3-hydroxyretinoic acid and their 4-oxo metabolites in human and animal plasma by high-performance liquid chromatography with automated column switching and UV detection

Journal of Pharmaceutical and Biomedical Analysis

Volumn 18, Issue 4-5, 1998, Pages 761-776

  Wyss, Ronald ^a   Bucheli, Franz ^a   Hartenbach, Roswitha ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

13 cis 3 Hydroxyretinoic acid; All trans 3 hydroxyretinoic acid; Column switching; Retinoids

Indexed keywords

3 HYDROXYRETINOIC ACID; 4 HYDROXY 3 OXORETINOIC ACID; 9 (4 HYDROXY 2,3,6 TRIMETHYLPHENYL) 3,7 DIMETHYL 2,4,6,8 NONATETRAENOIC ACID; DRUG METABOLITE; RETINOID; RO 12 7310 000; RO 127310; RO 14 7627 000; RO 18 5360 000; RO 61 6659 000; RO 61 9538 001; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOMATION; CONTROLLED STUDY; DOG; DRUG BLOOD LEVEL; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RABBIT; RAT; STEREOISOMERISM; TECHNIQUE; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; HUMANS; MICE; RABBITS; RATS; REPRODUCIBILITY OF RESULTS; RETINOIDS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032418708     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(98)00221-0     Document Type: Article

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