Inhibition of tumor invasion and metastasis by calcium spirulan (Ca- SP), a novel sulfated polysaccharide derived from a blue-green alga, Spirulina platensis

Clinical and Experimental Metastasis

Volumn 16, Issue 6, 1998, Pages 541-550

  Mishima, Takaaki ^a   Murata, Jun ^a,d   Toyoshima, Minako ^b   Fujii, Hideki ^a,c   Nakajima, Motowo ^b   Hayashi, Toshimitsu ^d   Kato, Toshimitsu ^e   Saiki, Ikuo ^a  

^a Research Institute for Wakan Yaku   (Japan)

^b NOVARTIS PHARMA K K   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d UNIVERSITY OF TOYAMA   (Japan)

^e DIC CORPORATION   (Japan)

Author keywords

Adhesion; Calcium spirulan; Invasion; Laminin; Metastasis

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM SPIRULAN; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLUE GREEN ALGA; CANCER CELL CULTURE; CANCER INHIBITION; COLON CARCINOMA; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; FEMALE; FIBROSARCOMA; HUMAN; HUMAN CELL; MALIGNANT NEOPLASTIC DISEASE; MELANOMA; METASTASIS INHIBITION; MOUSE; NONHUMAN;

ANIMALS; CELL ADHESION; CELL MOVEMENT; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG SCREENING ASSAYS, ANTITUMOR; EXTRACELLULAR MATRIX; FEMALE; LAMININ; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; METALLOENDOPEPTIDASES; MICE; MICE, INBRED C57BL; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; PLASMINOGEN; POLYSACCHARIDES; PROTEOGLYCANS; TUMOR CELLS, CULTURED;

EID: 0032417923     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006594318633     Document Type: Article

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