Effects of carotid sinus nerve transection on changes in neuropeptide Y and indolamines induced by long-term hypoxia in rats

Pflugers Archiv European Journal of Physiology

Volumn 437, Issue 1, 1998, Pages 130-138

  Poncet, Ludovic ^a   Denoroy, Luc ^a   Dalmas, Yvette ^a   Pequignot, Jean Marc ^a  

^a UNIVERSITÉ LYON 1   (France)

Author keywords

Brain; Carotid body; Hypoxia; Neuropeptide Y; Serotonin

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; NEUROPEPTIDE Y; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CAROTID SINUS; CHEMORECEPTOR; CONTROLLED STUDY; HYPOXIA; MALE; MEDULLA OBLONGATA; NERVE TRANSECTION; NEUROENDOCRINOLOGY; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SEROTONINERGIC SYSTEM;

ANIMALS; ANOXIA; BRAIN; CAROTID SINUS; CHEMORECEPTORS; CORPUS STRIATUM; DENERVATION; FRONTAL LOBE; HYDROXYINDOLEACETIC ACID; MALE; MEDULLA OBLONGATA; NERVE TISSUE PROTEINS; NEUROPEPTIDE Y; RAPHE NUCLEI; RATS; SEROTONIN;

EID: 0032417826     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240050757     Document Type: Article

References (29)

1. Akiyama Y, Koshimura K, Ohue T, Lee K, Miwa S, Yamagata S, Kikuchi H (1991) Effects of hypoxia on the activity of the dopaminergic neuron system in the rat striatum as studied by in vivo brain microdialysis. J Neurochem 57:997-1002
2. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal Biochem 72:248-254
3. Coleridge HM, Coleridge JCG, Jordan D (1991) Integration of ventilatory and cardiovascular control systems. In: Crystal RG, West JB (eds) The lung. Raven, New York, pp 1405-1418
4. Dalmuz Y, Pequignot JM, Cottet-Emard JM, Peyrin L (1994) Adrenal response to long-term hypoxia is still increased after carotid body denervation in rat. J Appl Physiol 76:1049-1054
5. Dampney RAL (1994) Functional organisation of central pathways regulating the cardiovascular system. Physiol Rev 74: 323-364
6. Dillon GH, Waldrop TG (1993) Responses of feline caudal hypothalamic cardiorespiratory neurons to hypoxia and hypercapnia. Exp Brain Res 96:260-272
7. Everitt BJ, Hökfelt T, Terenius L, Tatemoto K, Mutt V, Goldstein M (1984) Differential co-existence of neuropeptide Y (NPY)-like immunoreactivity with catecholamines in the central nervous system of the rat. Neuroscience 11:443-462
8. Finley JCW, Katz DM (1992) The central organization of carotid body afferent projections to the brainstem of the rat. Brain Res 572:108-116
9. Housley GD, Sinclair JD (1988) Localization by kainic acid lesions of neurones transmitting the carotid body chemoreceptor stimulus for respiration in rat. J Physiol (Lond) 406:99-114
10. Johnson TS, Young JB, Landsberg L (1983) Sympathoadrenal responses to acute and chronic hypoxia in the rat. J Clin Invest 71:1263-1272
11. 2 supply in rats. Respir Physiol 92:227-238
12. Lamanna JC, Vendel LM, Farrell RM (1992) Brain adaptation to chronic hypobaric hypoxia in rats. J Appl Physiol 72:2238-2243
13. Long S, Duffin J (1986) The neuronal determinants of respiratory rhythm. Prog Neurobiol 27:101-182
14. Majunidar S, Mills E, Smith PG (1983) Degenerative and regenerative changes in the central projection of glossopharyngeal and vagal sensory neurons after peripheral axotomy in cats: a structural basis for central reorganization of arterial chemoreflex pathways. Neuroscience 10:841-849
15. Martin-Body RL, Robson GJ, Sinclair JD (1985) Respiratory effects of sectioning the carotid sinus glossopharyngeal and abdominal vagal nerves in the awake rat. J Physiol (Lond) 361:35-45
16. Martin-Body RL, Robson GJ, Sinclair JD (1986) Restoration of hypoxic respiratory responses in the awake rat after carotid body denervation by sinus nerve section. J Physiol (Lond) 380:61-73
17. Morrison SF, Milner TA, Reis DJ (1988) Reticulo spinal vasomotor neurons of the rat rostral ventrolateral medulla: relationship to sympathetic nerve activity and the C1 adrenergic cell group. J Neurosci 8:1286-1301
18. Mortola JP, Gautier H (1995) Interaction between metabolism and ventilation: effects of respiratory gases and temperature. In: Dempsey JA, Pack AI (eds) Regulation of breathing. Dekker, New York, pp 1011-1063
19. Nolan PC, Waldrop TG (1993) In vivo and in vitro responses of neurons in the ventrolateral medulla to hypoxia. Brain Res 630:101-114
20. Nolan PC, Waldrop TG (1996) In vitro responses of VLM neurons to hypoxia after normobaric hypoxic acclimatization. Respir Physiol 105:23-33
21. Olson EB, Vidruk KH, Dempsey JA (1988) Carotid body excision significantly changes ventilatory control in awake rats. J Appl Physiol 64:666-671
22. Palkovits M, Brownstein MJ (1988) Maps and guide to microdissection of the rat brain. Elsevier, New York
23. Poncet L, Denoroy L, Dalmaz Y, Pequignot JM, Jouvet M (1996) Alteration in central and peripheral substance P-and neuropeptide Y-like immunoreactivity after chronic hypoxia in the rat. Brain Res 733:64-72
24. Poncet L, Denoroy L, Dalmaz Y, Pequignot JM (1997) Activity of tryptophan hydroxylase and content of indolamines in discrete brain regions after a long term hypoxic exposure in the rat. Brain Res 765:122-128
25. Ryan JW, Waldrop TG (1995) Hypoxia sensitive neurons in the caudal hypothalamus project to the periaqueductal gray. Respir Physiol 100:185-194
26. Sinclair JD (1987) Respiratory drive in hypoxia: carotid body and other mechanisms compared. News Pharmacol Sci 2:57-60
27. Soulier V, Cottet-Emard JM, Pequignot J, Hanchin F, Peyrin L, Pequignot JM (1992) Differential effects of long-term hypoxia on norepinephrine turnover in brain stem cell groups. J Appl Physiol 73:1810-1814
28. Sun MK, Reis DJ (1994) Hypoxia selectively excites vasomotor neurons of rostral ventrolateral medulla in rats. Am J Physiol 266:R245-R256
29. Vuillet J, Kerkerian L, Salin P, Nieoullon A (1989) Ultrastructural features of NPY-containing neurons in the rat striatum. Brain Res 477:241-251