Genomic organization and mutation analyses of the DR5/TRAIL receptor 2 gene in colorectal carcinomas

Cancer Letters

Volumn 133, Issue 2, 1998, Pages 197-204

  Arai, Takehiro ^a   Akiyama, Yoshimitsu ^a   Okabe, Satoshi ^a   Saito, Kiyoshi ^b   Iwai, Takehisa ^a   Yuasa, Yasuhito ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

Author keywords

Alternative splicing; Apoptosis; Colorectal cancer; DR5 TRAIL receptor 2 gene; Genomic structure

Indexed keywords

TUMOR NECROSIS FACTOR RECEPTOR;

ALTERNATIVE RNA SPLICING; APOPTOSIS; ARTICLE; COLORECTAL CARCINOMA; DNA SEQUENCE; GENE STRUCTURE; GENOME; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MUTATION; PRIORITY JOURNAL;

APOPTOSIS; BASE SEQUENCE; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; EXONS; GENOME, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; SEQUENCE ALIGNMENT;

EID: 0032416597     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(98)00230-4     Document Type: Article

References (27)

1. Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1995;1456-1462.
2. Bedi A., Pasricha P.J., Akhtar A.J., Barber J.P., Bedi G.C., Giardiello F.M., Zehnbauer B.A., Hamilton S.R., Jones R.J. Inhibition of apoptosis during development of colorectal cancer. Cancer Res. 55:1995;1811-1816.
3. Morin P.J., Vogelstein B., Kinzler K.W. Apoptosis and APC in colorectal tumorigenesis. Proc. Natl. Acad. Sci. USA. 93:1996;7950-7954.
4. Shaw P., Bovey R., Tardy S., Sahli R., Sordat B., Costa J. Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line. Proc. Natl. Acad. Sci. USA. 89:1992;4495-4499.
5. Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365.
6. Landowski T.H., Qu N., Buyuksal I., Painter J.S., Dalton W.S. Mutations in the Fas antigen in patients with multiple myeloma. Blood. 90:1997;4266-4270.
7. Pan G., Ni J., Wei Y.-F., Yu G.-I., Gentz R., Dixit V.M. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science. 277:1997;815-818.
8. Sheridan J.P., Marsters S.A., Pitti R.M., Gurney A., Skubatch M., Baldwin D., Ramakrishnan L., Gray C.L., Baker K., Wood W.I., Goddard A.D., Godowski P. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science. 277:1997;818-821.
9. MacFarlane M., Ahmad M., Srinivasula S.M., Fernandes-Alnemri T., Cohen G.M., Alnemri E.S. Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL. J. Biol. Chem. 272:1997;25417-25420.
10. Schneider P., Bodmer J.-L., Thome M., Hofmann K., Holler N., Tschopp J. Characterization of two receptors for TRAIL. FEBS Lett. 416:1997;329-334.
11. Screaton G.R., Mongkolsapaya J., Xu X.-N., Cowper A.E., McMichael A.J., Bell J.O. TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL. Curr. Biol. 7:1997;693-696.
12. Wu G.S., Burns T.F., McDonald E.R. III, Jiang W., Meng R., Krantz I.D., Kao G., Gan D.-D., Zhou J.-Y., Muschel R., Hamilton S.R., Spinner N.B., Markowitz S., Wu G., El-Deiry W.S. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat. Genet. 17:1997;141-143.
13. Walczak H., Degli-Esposti M.A., Johnson R.S., Smolak P.J., Waugh J.Y., Boiani N., Timour M.S., Gerhart M.J., Schooley K.A., Smith F.A., Goodwin R.G., Rauch C. TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J. 16:1997;5386-5397.
14. Sheikh M.S., Burns T.F., Huang Y., Wu G.S., Amundson S., Brooks K.S., Fornace A.J. Jr., El-Deiry W.S. p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor α Cancer Res. 58:1998;1593-1598.
15. Marsters S.A., Sheridan J.P., Pitti R.M., Huang A., Skubatch M., Baldwin D., Yuan J., Gurney A., Goddard A.D., Godowski P., Ashkenazi A. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr. Biol. 7:1997;1003-1006.
16. Farrington S.M., Cunningham C., Boyle S.M., Wyllie A.H., Dunlop M.G. Detailed physical and deletion mapping of 8p with isolation of YAC clones from tumor suppressor loci involved in colorectal cancer. Oncogene. 12:1996;1803-1808.
17. Gustafson C.E., Wilson P.J., Lukeis R., Baker E., Woollatt E., Annab L., Hawke L., Barrett J.C., Chenevix-Trench G. Functional evidence for a colorectal cancer tumor suppressor gene at chromosome 8p22-23 by monochromosome transfer. Cancer Res. 56:1996;5238-5245.
18. T. Arai, Y. Akiyama, A. Yamamura, Y. Hosoi, T. Shibata, K. Saitoh, S. Okabe, Y. Yuasa, Allelotype analysis of early colorectal cancers with lymph node metastasis, Int. J. Cancer (1998), in press.
19. Orlinick J.R., Vaishnaw A., Elkon K.B., Chao M.V. Requirement of cysteine-rich repeats of the Fas receptor for binding by the Fas ligand. J. Biol. Chem. 272:1997;28889-28894.
20. Cascino I., Fiucci G., Ruberti G. Three functional soluble form of the human apoptosis-inducing Fas molecule are produced by alternative splicing. J. Immunol. 154:1995;2706-2713.
21. Goelz S.E., Hamilton S.R., Vogelstein B. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem. Biophys. Res. Commun. 130:1985;118-126.
22. Siebert P.D., Chenchik A., Kellogg D.E., Lukyanov K.A., Lukyanov S.A. An improved PCR method for walking in uncloned genomic DNA. Nucleic Acids Res. 23:1994;1087-1088.
23. Oto M., Miyake S., Yuasa Y. Optimization of nonradioisotopic single strand conformation polymorphism analysis with a conventional minislab gel electrophoresis apparatus. Anal. Biochem. 213:1993;19-22.
24. Pan G., O'Rourke K., Chinnaiyan A.M., Gentz R., Ebner R., Ni J., Dixit M. The receptor for cytotoxic ligand TRAIL. Science. 276:1997;111-113.
25. Fisher G.H., Rosenberg F.J., Straus S.E., Dale J.K., Middelton L.A., Lin A.Y., Strober W., Lenardo M.J., Puck J.M. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell. 81:1995;935-946.
26. Rieux-Laucat F., Le Deist F., Hivroz C., Roberts I.A.G., Debatin K.M., Fischer A., de Villartay J.P. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science. 268:1995;1347-1349.
27. Schneider P., Thome M., Burns K., Bodmer J.-L., Hofmann K., Kataoka T., Holler N., Tschopp J. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and active NF-κB. Immunity. 7:1997;831-836.