Disruption of axonal transport from olfactory epithelium by 3-methylindole

Physiology and Behavior

Volumn 65, Issue 3, 1998, Pages 479-487

  Setzer, Angela K ^a   Slotnick, Burton ^b  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b AMERICAN UNIVERSITY   (United States)

Author keywords

3 Methylindole; Axonal transport; Olfactory bulb

Indexed keywords

HORSERADISH PEROXIDASE; SKATOLE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; HISTOLOGY; INTRACELLULAR TRANSPORT; INTRAPERITONEAL DRUG ADMINISTRATION; NERVE FIBER TRANSPORT; NONHUMAN; OLFACTORY BULB; OLFACTORY EPITHELIUM; PRIORITY JOURNAL; RAT;

EID: 0032416325     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(98)00185-1     Document Type: Article

References (12)

1. Bray, T. M.; Kubow, S.: Involvement of free radicals in the mechanism of 3-methylindole-induced pulmonary toxicity: An example of metabolic activation in chemically induced lung disease. Environ. Health Perspect. 64:61-67; 1985.
2. Gaskell, B. A.: Nonneoplastic changes in the olfactory epithelium: Experimental studies. Environ. Health Perspect. 85:275-289; 1990.
3. Mesulam, M.: Tracing neural connections with horseradish peroxidase. New York: Wiley; 1982.
4. Peele, D. B.; Allison, S. D.; Bolon, B.; Prah, D.; Jensen, K. F.; Morgan, K. T.: Functional deficits produced by 3-methylindole-induced olfactory mucosal damage revealed by a simple olfactory learning task. Toxicol. Appl. Pharmacol. 107:191-202; 1991.
5. Ressler, K. J.; Sullivan, S. L.; Buck, L. B.: Information coding in the olfactory system: Evidence for a stereotyped and highly orga-nized epitope map in the olfactory bulb. Cell 79:1245-1255; 1994.
6. Shipley, M. T.: Transport of molecules from nose to brain: Transneuronal anterograde and retrograde labeling in the rat olfactory system by wheat germ agglutinin-horseradish peroxidase applied to the nasal epithelium. Brain Res. Bull. 15:129-142; 1985.
7. Slotnick, B. M.; Hersch, S.: A stereotaxic atlas of the rat olfactory system. Brain Res. Bull. 5(Suppl. 5):1-55; 1980.
8. Turk, M. A. M.; Flory, W.; Henk, W. G.: Dose response in 3-methylindole-induced bronchiolar epithelial necrosis in mice. Res. Commun. Chem. Pathol. Pharmacol. 46:351-403; 1984.
9. Turk, M. A. M.; Flory, W.; Henk, W. G.: Chemical modulation of 3-methlyindole toxicosis in mice: Effect on bronchiolar and olfactory mucosal injury. Vet. Pathol. 23:563-570; 1986.
10. Turk, M. A. M.; Henk, W. G.; Flory, W.: 3-Methylindole-induced nasal mucosal damage in mice. Vet. Pathol. 24:400-403; 1987.
11. Vassar, R.; Chao, S. K.; Sitcheran, R.; Nunez, J. M.; Vosshall, L. B.; Axel, R.: Topographic organization of sensory projections to the olfactory bulb. Cell 79:981-991; 1994.
12. Walters, E.; Buchheit, K.; Maruniak, J. A.: Olfactory cytochrome P-450 immunoreactivity in mice is altered by dichlobinil but preserved by metyrapone. Toxicology 81:113-122; 1993.