Anti-GM3 antibodies activate calcium inflow and inhibit platelet-derived growth factor beta receptors (PDGFβr) in T51B rat liver epithelial cells

Glycobiology

Volumn 8, Issue 12, 1998, Pages 1221-1225

  Golard, Andre ^a  

^a NORTHWEST HOSPITAL   (United States)

Author keywords

Calcium; Gangliosides; GM3; Liver; Signal transduction

Indexed keywords

ANTIBODY; BETA ADRENERGIC RECEPTOR; EPIDERMAL GROWTH FACTOR; GANGLIOSIDE GM3; GLYCOCONJUGATE; GLYCOLIPID; PLATELET DERIVED GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE; CONTROLLED STUDY; EPITHELIUM CELL; FLOW CYTOMETRY; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; CALCIUM; CELLS, CULTURED; FLOW CYTOMETRY; G(M3) GANGLIOSIDE; GLYCOCONJUGATES; GLYCOLIPIDS; LIVER; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR;

ANIMALIA;

EID: 0032415074     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/8.12.1221     Document Type: Article

References (45)

1. Brabyn, C.J. and Kleine, L.P. (1995) EGF causes hyperproliferation and apoptosis in T51B cells: Involvement of high and low affinity EGFR binding sites. Cell. Signalling, 7, 139-150.
2. Bremer, E.G., Hakomori, S., Bowen-Pope, D.F., Raines, E. and Ross, R. (1984) Ganglioside-mediated modulation of cell growth, growth factor binding, and receptor phosphorylation. J. Biol. Chem., 259, 6818-6825.
3. 3 on tyrosine phosphorylation of the epidermal growth factor. J. Biol. Chem., 261, 2434-2440.
4. Carlson, R.O., Masco, D., Brooker, G. and Spiegel, S. (1994) Endogenous ganglioside GM1 modulates L-type calcium channel activity in N18 neuroblastoma cells. J. Neurosci., 14, 2272-2281.
5. Chen, W.S., Lazar, C.S., Poenie, M., Tsien, R.Y., Gill, G.N. and Rosenfeld, M.G. (1987) Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature, 328, 820-823.
6. Cheresh, D.A., Pytela, R., Pierschbacher, M.D., Klier, F.G., Ruoslahti, E. and Reisfeld, R.A. (1987) An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in a divalent cation-dependent functional complex with the disialoganglioside GD2. J. Cell Biol., 105, 1163-1173.
7. Dean, N.M. and Boynton, A.L. (1995) EGF-induced increase in diacylglycerol, choline release, and DNA synthesis is extracellular calcium dependent. J. Cell Physiol., 164, 449-458.
8. Dixon, S.J., Stewart, D., Grinstein, S. and Spiegel, S. (1987) Transmembrane signaling by the B subunit of cholera toxin: increased cytoplasmic free calcium in rat lymphocytes. J. Cell Biol., 105, 1153-1161.
9. Dohi, T., Nores, G. and Hakomori, S.-I. (1988) An IgC53 monoclonal antibody established after immunization with GM3 lactone: immunochemical specificity and inhibition of melanoma cell growth in vitro and in vivo. Cancer Res., 48, 5680-5685.
10. Dyatlovitskaya, E.V. and Bergelson, L.D. (1987) Glycosphingolipids and antitumor immunity. Biochem. Biophys. Acta, 907, 125-143.
11. + channels by GM1 ganglioside. Biochem. Biophys. Res. Commun., 200, 1341-1345.
12. Fish, R.G. (1996) Role of gangliosides in tumour progression: a molecular target for cancer therapy? Med. Hypotheses, 46, 140-144.
13. Gleeson, P.A. (1994) Glycoconjugates in autoimmunity. Biochim. Biophys. Acta, 1197, 237-255.
14. Golard, A. (1995) Lectins modulate calcium channels in chick sympathetic ganglia. Neuroscience, 69, 331-337.
15. Guan, Z., Stokes, B.T., Van Brocklyn, J. and Yates, A.J. (1992) Gangliosides inhibit platelet-derived growth factor-stimulated increases in intracellular calcium in Swiss 3T3 cells. Biochem. Biophys. Acta. 1136, 315-318.
16. Hakomori, S.-I. and Zhang, Y. (1997) Glycosphingolipid antigens and cancer therapy. Chem. Biol., 4, 97-104.
17. Hattori, M.-A., Horiuchi, K. Hosaka, K., Hayashi, H. and Kojima, I. (1995) Sialyl-lactose-mediated cell interaction during granulosa cell differentiation. Identification of its binding proteins. J. Biol. Chem., 270, 7858-7863.
18. M1 ganglioside in PC12 cells. J. Biol. Chem., 267, 24789-24795.
19. Hill, T.D., Kindmark, H. and Boynton, A.L. (1988) Epidermal growth factor-stimulated DNA synthesis requires an influx of extracellular calcium. J. Cell. Biochem., 38, 137-144.
20. Hille, B. (1994) Modulation of ion channel function by G-protein-coupled receptors. Trends Neurosci., 17, 331-336.
21. Hynds, D.L., Summers, M., Van Brocklyn, J., O'Dorisio, M.S. and Yates, A.J. (1993) Gangliosides inhibit platelet-derived growth factor-stimulated growth, receptor phosphorylation, and dimerization in neuroblastoma SH-SY5Y cells. J. Neurochem., 65, 2251-2258.
22. 2+ level in different cell types. Life Sci., 57, 449-436.
23. Kirillova, J., Thomas, P. and Almers, W. (1993) Two independently regulated secretory pathways in mast cells. J. Physiol., 87, 203-208.
24. Kobata, A. (1992) Structures and functions of the sugar chains of glycoproteins. Eur. J. Biochem., 209, 483-501.
25. Kojima, N. and Hakomori, S.-I. (1991) Cell adhesion, spreading, and motility of GM3-expressing cells based on glycolipid glycolipid interaction. J. Biol. Chem., 266, 17552-17558.
26. Lopez, M.G., Albillos, A., de la Fuente, M.T., Borges, R. Gandia, L., Carbone, E. Garcia, A.G. and Artalejo, A.R. (1994) Localized L-type calcium channels control exocytosis in cat chromaffin cells. Pfluegers Arch. Eur J. Physiol., 427, 348-354.
27. Matsuo, T., Hazeki, K., Haseki, O., Katada, T. and Ui.M. (1996) Activation of phosphatidylinositol 3-kinase by concanavalin A through dual signaling pathways, G-protein-coupled and phosphotyrosine-related, and an essential role of the G-protein-coupled signals for the lectin-induced respiratory burst in human monocyte THP-1 cells. Biochem. J., 315, 505-512.
28. Nagai, Y. and Tsuji, S. (1994) Significance of ganglioside-mediated glycosignal transduction in neuronal differentiation and development. Prog. Brain. Res., 101, 119-125.
29. Nishiyama, A., Lin, X.-H., Giese, N., Heldin, C.-H. and Stallcup, W.B. (1996) Interaction between NG2 protcoglycan and PDGF α-receptor on O2A progenitor cells is required for optimal response to PDGF. J. Neurosci. Res., 43, 315-330.
30. Ortaldo, J.R., Mason, A.T., Longo, D.L., Beckwith, M., Creekmore, S.P. and McVicar, D.W. (1996) T cell activation via the disialoganglioside GD3: analysis of signal transduction. J. Leuk. Biol., 60, 533-539.
31. Reisfeld, R.A., Mueller, B.M., Handgretinger, R., Yu, A.L. and Gillies, S.D. (1994) Potential of genetically engineered anti-ganglioside GD2 antibodies for cancer immunotherapy. Prog. Brain. Res., 101, 201-212.
32. Rosen, L.B. and Greenberg, M.E. (1996) Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels. Proc. Natl. Acad. Sci. USA, 93, 1113-1118.
33. Sachinidis, A., Kraus, R., Seul, C., Meyer zu Brickwedde, M.K., Schulte, K., Ko, Y., Hoppe, J. and Vetter, H. (1996) Gangliosides GM1, GM2 and GM3 inhibit the platelet-derived growth factor-induced signaling transduction pathway in vascular smooth muscle cells by different mechanisms. Eur. J. Cell Biol., 71, 79-88.
34. Saqr, H.E., Walters, J.D. Guan, Z., Stokes, B.T. Yates, A.J. (1995) Gangliosides inhibit PDGF-induced signal trasduction events in U-1242 MG human glioma cells. Neurochem. Res., 20, 1389-1395.
35. Slomiany, B.L., Liu, J. Yao, P. and Slomiany, A. (1992) GM1-ganglioside regulation of EGF-induced gastric mucosal calcium channel activation. Gen. Pharmacol., 23, 799-803.
36. 2+ influx and acetylcholine release in brain synaptosomes. NeuroReport, 8, 2203-2207.
37. Tse, A., Tse, F.W., Almers, W. and Hille, B. (1993) Rhytmic exocytosis stimulated by GnRH-induced calcium oscillations in rat gonadotropes. Science, 260, 82-84.
38. Wu, G. and Ledeen, R.W. (1994) Gangliosides as modulators of neuronal calcium. Prog. Brain. Res., 101, 101-112.
39. Wu, G., Lu, Z.-H., Nakamura, K., Spray, D.C. and Ledeen, R.W. (1996) Trophic effect of cholera toxin B subunit in cultured cerebellar granule neurons: modulation of intracellular calcium by GM1 ganglioside. J. Neurosci. Res., 44, 243-254.
40. Yamamura, S., Handa, K. and Hakomori, S.-I. (1997) A close association of GM3 with c-Src and Rho in GM3-enriched microdomains at the B16 melanoma cell surface membrane: a preliminary note. Biochem. Biophys. Res. Commun., 236, 218-222.
41. Yang, L.J., Zeller, C.B., Shaper, N.L., Kiso, M., Hasegawa, A., Shapiro, R.E. and Schnaar, R.L. (1996) Gangliosides are neuronal ligands for myelin-associated glycoprotein. Proc. Natl. Acad. Sci. USA, 93, 814-818.
42. Yates, A.J., VanBrocklyn, J., Saqr, H.E., Guan, Z., Stokes, B.T. and O'Dorisio, M.S. (1993) Mechanisms through which gangliosides inhibit PDGF-stimulated mitogenesis in intact Swiss 3T3 cells: receptor tyrosine phosphorylation, intracellular calcium, and receptor binding. Exp. Cell. Res., 204, 38-45.
43. Yatomi, Y. Igarashi, Y. and Hakomori, S.-I. (1996) Effects of exogenous gangliosides on intracellular Ca2+ mobilization and functional responses in human platelets. Glycobiology, 6, 347-353.
44. Young, W.W.,Jr, Portoukalian, J. and Hakomori, S.-I. (1981) Two monoclonal anticarbohydrate antibodies directed to glycosphingolipids with a lacto-N-glycosyl type II chain. J. Biol. Chem., 256, 10967-10972.
45. Zeng, F.-Y., Benguria, A., Kafert, S., Andre, S., Gabius, H.-J. and Villalobo, A. (1995) Differential response of epidermal growth factor receptor tyrosine kinase activity to several plant and mammalian lectins. Mol. Cell. Biochem., 142, 117-124.