Synthesis, toxicological, and pharmacological assessment of derivatives of 2-aryl-4-(3-arylpropyl)morpholines

Archiv der Pharmazie

Volumn 331, Issue 11, 1998, Pages 342-346

  Avramova, Petya ^a   Danchev, Nicolai ^a   Buyukliev, Rossen ^a   Bogoslovova, Tatiana ^a  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

2 Aryl 4 (3 arylpropyl) morpholine derivatives; Acute toxicity; Antidepressive activity; MAO inhibition

Indexed keywords

4 (2 BENZOYLETHYL) 2 PHENYL 3 METHYL MORPHOLINE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; MOCLOBEMIDE; MONOAMINE OXIDASE A INHIBITOR; MONOAMINE OXIDASE B INHIBITOR; MORPHOLINE DERIVATIVE; PHENETHYLAMINE; SELEGILINE; SEROTONIN; TYRAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN MITOCHONDRION; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; INFRARED SPECTROSCOPY; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; SLEEP TIME; TOXICITY TESTING;

ANIMALS; ANTIDEPRESSIVE AGENTS; LETHAL DOSE 50; MALE; MICE; MONOAMINE OXIDASE INHIBITORS; MORPHOLINES; MOTOR ACTIVITY; RATS; SLEEP; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0032414769     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(199811)331:11<342::AID-ARDP342>3.0.CO;2-6     Document Type: Article

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