Experimental studies on the antitussive properties of the new xanthine derivative 1H-purine-2,6-dione, 3,7-dihydro-3-methyl-7[(5-methyl-1,2,4- oxadiazol-3-yl) methyl]: 3rd communication: Examinations on opioid mechanisms and physical drug dependence

Arzneimittel-Forschung/Drug Research

Volumn 48, Issue 12, 1998, Pages 1147-1155

  Kapui, Zoltán ^a   Mikus, Endre Gustáv ^a   Bence, Judit ^a   Gerber, Katalin ^a   Boér, Klinga ^a   Korbonits, Dezsõ ^a   Borsodi, Anna ^b   Arányi, Péter ^a  

^a Chinoin Pharmaceutical and Chemical Works Ltd   (Hungary)

^b INSTITUTE OF BIOCHEMISTRY   (Hungary)

Author keywords

1H Purine 2,6 dione, 3,7 dihydro 3 methyl 7 (5 methyl 1,2,4 oxadiazol 3 yl)methyl ; Antitussives; CAS 115779 20 9; CH 13584, drug dependence studies, opioid mechanisms; Codeine; Dextromethorphan; Morphine; Naloxone

Indexed keywords

1H PURINE 2,6 DIONE, 3,7 DIHYDRO 3 METHYL 7[(5 METHYL 1,2,4 OXADIAZOL 3 YL) METHYL]; BETA FUNALTREXAMINE; CH 13584; CODEINE; DELTA OPIATE RECEPTOR; DIPRENORPHINE; KAPPA OPIATE RECEPTOR; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; NORBINALTORPHIMINE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; COUGHING; DRUG ANTAGONISM; DRUG DEPENDENCE; DRUG RECEPTOR BINDING; DRUG WITHDRAWAL; GUINEA PIG; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; NONHUMAN; RAT; WITHDRAWAL SYNDROME;

ANIMALS; ANTITUSSIVE AGENTS; BINDING, COMPETITIVE; COUGH; GUINEA PIGS; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; NARCOTIC ANTAGONISTS; OXADIAZOLES; PURINES; RATS; RATS, WISTAR; RECEPTORS, OPIOID; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS;

EID: 0032414694     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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