Laser scanning cytometry quantification of estrogen receptors in breast cancer

Analytical and Quantitative Cytology and Histology

Volumn 20, Issue 6, 1998, Pages 470-476

  Gorczyca, Wojciech ^a   Davidian, Marianna ^a   Gherson, Janine ^a   Ashikari, Roy ^b   Darzynkiewicz, Zbigniew ^a   Melamed, Myron R ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b St Agnes Hospital White Plains   (United States)

Author keywords

Breast neoplasms; Cytometry, image; Laser scanning cytometry; Receptors estrogen

Indexed keywords

ESTROGEN RECEPTOR;

ARTICLE; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOMETRY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LASER MICROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BREAST NEOPLASMS; FEMALE; FLUORESCENCE; HUMANS; IMAGE CYTOMETRY; IMMUNOENZYME TECHNIQUES; IMMUNOHISTOCHEMISTRY; LASERS; RECEPTORS, ESTROGEN;

EID: 0032412340     PISSN: 08846812     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Allred DD: Should immunohistochemical examination replace biochemical hormone receptor assays in breast cancer? Am J Clin Pathol 1993;99:1-2
2. Battifora H, Mehta P, Ahn C, Felder B: Estrogen receptor immunohistochemical assay in paraffin-embedded tissue: A better gold standard? Appl Immunohistochem 1993;1:39-45
3. Benitez Bribiesca L, Guevara R, Ruiz MT, Martinez G, Rodriguez Cuevas S: A simplified histoscore for the estrogen receptor assay in breast cancer. Pathol Res Pract 1992;188:461-465
4. Esteban JM, Ahn C, Battifora H, Felder B: Predictive value of estrogen receptors evaluated by quantitative immunohistochemical analysis in breast cancer. Am J Clin Pathol 1994;102:S9-12
5. Estaban JM, Ahn C, Mehta P, Battifora H: Biologic significance of quantitative estrogen receptor immunohistochemical assay by image analysis in breast cancer. Am J Clin Pathol 1994;102:158-162
6. Gorczyca W, Darzynkiewicz Z, Melamed MR: Laser scanning cytometry in pathology of solid tumors: A review. Acta Cytol 1997;41:98-108
7. Gorczyca W, Sarode V, Juan G, Melamed MR, Darzynkiewicz Z: Laser scanning cytometric analysis of cyclin B1 in primary human malignancies. Mod Pathol 1997;10:457-462
8. Hendricks JB, Wilkinson EJ: Comparison of two antibodies for evaluation of estrogen receptors in paraffin-embedded tumors. Mod Pathol 1993;6:765-770
9. Kamentsky LA, Burger DE, Gershman RJ, Kamentsky LD, Luther E: Slide-based laser scanning cytometry. Acta Cytol 1997;41:123-143
10. Kamentsky LA, Kamentsky LD: Microscope-based multiparameter laser scanning cytometer yielding data comparable to flow cytometry data. Cytometry 1991;12:381-387
11. McGuire WL: Steroid hormone receptors in breast can-cer treatment strategy. Rec Prog Hormone Res 1980;36:135-156
12. Nichols GE, Frierson HF, Boyd JC, Hanigan MH: Automated immunohistochemical assay for estrogen receptor status in breast cancer using monoclonal antibody CC4-5 on the Ventana. Am J Clin Pathol 1996;106:332-338
13. Nicholson RI, McClelland RA, Gee JM: Steroid hormone receptors and their clinical significance in cancer. Am J Clin Pathol 1995;48:890-895
14. Parl FF, Posey YF: Discrepancies of the biochemical and immunohistochemical estrogen receptor assays in breast cancer. Hum Pathol 1988;19:960-966
15. Pertschuk LP, Feldman JG, Kim YD, Braithwaite L, Schneider F, Bravermen AS, Axiotis C: Estrogen receptor immunocytochemistry in paraffin embedded tissues with ER1D5 predicts breast cancer endocrine response more accurately than H222Sp gamma in frozen sections or cytosol-based ligand-binding assays [see Comments]. Cancer 1996;77:2514-2519
16. Querzoli P, Ferretti S, Albonico G, Magri E, Scopoli D, Indelli M, Nenci I: Application of quantitative analysis to biologic profile evaluation in breast cancer. Cancer 1995;76:2510-2517
17. Remmele W, Schicketanz KH: Immunohistochemical determination of estrogen and progesterone receptor content in human breast cancer: Computer-assisted image analysis (QIC score) vs. subjective grading (IRS). Pathol Res Pract 1993;189:862-866
18. Sklarew RJ, Bodmer SC, Pertschuk LP: Quantitative imaging of immunocytochemical (PAP) estrogen receptor staining patterns in breast cancer sections. Cytometry 1990;11:359-378
19. Snead DR, Bell JA, Dixon AR, Nicholson R, Eiston CW, Blarney RW, Ellis IO: Methodology of immunohistological detection of oestrogen receptor in human breast carcinoma in formalin-fixed, paraffin-embedded tissue: A comparison with frozen section methodology. Histopathology 1993;23:233-238