Comparison of IL-10 levels in chronic venous insufficiency ulcers and autologous donor tissue

Archives of Dermatological Research

Volumn 290, Issue 12, 1998, Pages 669-673

  Lundberg, Justin E ^a   Roth, Timothy P ^a   Dunn, Raymond M ^a   Doyle, James W ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Cytokines; Inflammation; Venous ulcers; Wound healing

Indexed keywords

CYTOKINE; INTERLEUKIN 10;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; CHEMOLUMINESCENCE; CHRONIC DISEASE; CHRONIC VEIN INSUFFICIENCY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENSITOMETRY; DONOR; FROZEN SECTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LEG ULCER; PRIORITY JOURNAL; STAINING; WESTERN BLOTTING; WOUND; WOUND HEALING;

BLOTTING, WESTERN; CHRONIC DISEASE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-10; PRECIPITIN TESTS; ULCER; VENOUS INSUFFICIENCY; WOUND HEALING;

EID: 0032411698     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004030050371     Document Type: Article

References (24)

1. Abrams JS, Roncarolo MG, Yssel H, Anderson U, Gleich GJ, Silver JE (1992) Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL10 and IL-5 in clinical samples. Immunol Rev 127:5-24
2. Barbul A, Regan MC (1990) The regulatory role of T lymphocytes in wound healing. J Trauma 30 [Suppl N12]:S97-S100
3. Calvin M (1998) Cutaneous wound repair. Wounds 10(1): 12-32
4. Chang C-H, Furue M, Tamaki K (1995) B7-1 expression of Langerhans cells is up-regulated by proinflammatory cytokines, and is down-regulated by interferon-γ or by interleukin-10. Eur J Immunol 25:394-398
5. Cheatle TR, Sarin S, Coleridge Smith PD, Scurr JH (1991) The pathogenesis of skin damage in venous disease: a review. Eur J Vasc Surg 5: 115-123
6. Da Costa RM, Aniceto C, Jesus FM, Mendes M (1994) Quick healing of leg ulcers after molgramostim. Lancet 344:481-482
7. Dale JJ, CaHam MJ, Ruckley CV, Harper DR, Berrer PN (1983) Chronic ulcers of the leg: a study of prevalence in Scottish community. Health Bull 41:310-314
8. Ding L, Linsley PS, Huang L-Y, Germain RN, Shevach EM (1993) IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J Immunol 151:1224-1234
9. Enk A, Angeloni VL, Udey MC, Katz SI (1993) Inhibition of Langerhans cell antigen-presenting function by IL-10. A role of IL-10 in the induction of tolerance. J Immunol 151: 2390-2398
10. Falanga V, Eaglestein WH (1986) A therapeutic approach to venous ulcers. J Am Acad Dermatol 14:777-784
11. Fitzpatrick JE (1989) Stasis ulcers: update on a common geriatric problem. Geriatrics 44:19-31
12. Kaplan G, Walsh G, Guido LS, Meyn P, Burkhardt RA, Abalos RM, Barker J, Frindt PA, Fajardo TT, Celona R, Cohn ZA (1992) Novel responses of human skin to intradermal recombinant granulocyte/macrophage-colony-stimulating factor: Langerhans cell recruitment, keratinocyte growth, and enhanced wound healing. J Exp Med 175: 1717-1728
13. Li Y-Q, Doyle JW, Roth TP, Dunn RM, Lawrence WT (1998) IL-10 and GM-CSF expression and the presence of antigen presenting cells in chronic venous ulcers. J Surg Res 79: 128-135
14. Liebovich SJ, Ross R (1975) The role of the marcophage in wound repair. Am J Pathol 78:71-100
15. Martin P (1997) Wound healing - aiming for perfect skin regeneration. Science 276:75-81
16. Mertz PM, DeWitt DL, Stetler-Stevenson WG, Wahl LM (1994) Interleukin-10 suppression of monocyte prostaglandin H synthase-2. Mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production. J Biol Chem 269: 21322-21329
17. Miller WL (1992) Chronic venous insufficiency. Cardiovasc Clin 22:67-80
18. Reitamo S, Remitz A, Tamai K, Uitto J (1994) Interleukin-10 modulates type I collagen and matrix metalloprotease gene expression in cultured human skin fibroblasts. J Clin Invest 94: 2489-2492
19. Sandberg N (1964) Time relationship between administration of cortisone and wound healing in rats. Acta Chir Scand 127: 446-455
20. Simpson DM, Ross R (1971) Effects of heterologous antineutrophil serum in guinea pigs: hematologic and ultrastructural observations. Am J Pathol 65:49-102
21. Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC (1985) Measurement of protein using bichinchoninic acid protein assay. Anal Biochem 150:76-85
22. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76: 4350-4354
23. Waal Malefyt R de, Abrams J, Bennett B, Figdor CG, Vries JE de (1991a) Interleukin-10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 174: 1209-1220
24. Waal Malefyt R de, Haanen J, Spits H, Ronccarolo M-G, Velde A te, Figdor C, Johnson K, Kastelein R, Yssel H, Vries JE de (1991b) Interleukin-10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 174:915-924