Determination of two metabolites of albendazole, albendazole-sulfoxide and albendazole-sulfone in cow's milk using an HPLC method - A systematic approach to optimise extraction conditions -

Chromatographia

Volumn 48, Issue 11-12, 1998, Pages 777-784

  Romvari Zs ^a   Fekete, J ^a   Kemeny S ^a   Pokol, G ^a   Gebefugi I ^b   Kettrup, A ^b  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Albendazole metabolites; Column liquid chromatography; Milk samples; Sample treatment optimisation; Solid phase extraction; Taguchi method

Indexed keywords

ALBENDAZOLE; ALBENDAZOLE SULFONE; ALBENDAZOLE SULFOXIDE; DRUG METABOLITE;

ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG MILK LEVEL; FOOD ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MILK; NONHUMAN; PRIORITY JOURNAL; SOLID PHASE EXTRACTION;

EID: 0032411374     PISSN: 00095893     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02467647     Document Type: Article

References (13)

1. D. L. Morris, P. W. Dykes, B. Dickson, S. E. Marriner, J. A. Bogan, F. G. Burnows, Br. Med. J. 286, 103 (1983).
2. R. J. Gyuric, A. W. Chow, B. Zaber, E. L. Brunner, J. A. Miller, A. J. Villani, L. A. Petka, R. C., Parish, Am. Soc. for Pharm. and Exp. Ther. 9, 503 (1981).
3. A. M. Marti, A. E. Mooser, H. Koch, J. Chromatogr, 498, 145 (1990).
4. S. A. Barker, T. McDowell, B. Charkhian, L. C. Hsieh, C. R. Short, J. Assoc. Off. Anal. Chem. 73, 22 (1990).
5. P. Galtier, M. Alvinerie, J. L. Steimer, P. Francheteau, Y. Plusquellec, G. Houin, J. of Pharm. Sci. 80, 3 (1991).
6. P. E. Hoaksey, K. Awadzi, S. A. Ward, P. A. Coventry, M. L. E. Orme, G. Edwards, J. Chromatogr. 566, 244(1991).
7. E. Ludwig, A. Csiba, Municipal Hospital in Péterfy S. Street 1991.
8. A. Macri, G. Bambilla, C. Civitareale, A. Bocca, Ital. J. Food Sci. 3, 239 (1993).
9. P. S. Chu, R. Y. Wang, T. A. Brandt, C. A. Weerasinghe, J. Chromatogr. 620, 129 (1993).
10. M. Hurtado, M. T. Media, J. Solelo, H. Jung, J. Chromatogr. 494, 403 (1989).
11. Zs. Romvári, S. Kemény, G. Pokol, J. Fekete; A new approach for development of rugged sample preparation of metabolites of albendazole cow milk; Microchimica Acta; accepted for publication.
12. V. N. Nair Ed., Taguchi's parameter design: A panel discussion, Technometrics 34, 127 (1992).
13. G. E. P. Box, W. G. Hunter, J. S. Hunter, Statistic for Experiments. John Wiley & Sons, 1978.