Suppression of albumin and α-fetoprotein gene expression by butyrolactone I, a selective inhibitor of the cdk family, in HuH-7 human hepatoma cells

Anticancer Research

Volumn 18, Issue 6 A, 1998, Pages 4317-4322

  Hida, Daisaku ^a   Nakata, Keisuke ^a   Shima, Yuka ^a   Migita, Kiyoshi ^a   Nakao, Kazuhiko ^a   Kato, Yuji ^a   Ishii, Nobuko ^a   Eguchi, Katsumi ^a  

^a NAGASAKI UNIVERSITY   (Japan)

Author keywords

fetoprotein; Albumin; Butyrolactone I; Hepatocyte nuclear factor 1; HuH 7

Indexed keywords

ALBUMIN; ALPHA FETOPROTEIN; BUTYROLACTONE I; CHLORAMPHENICOL ACETYLTRANSFERASE; CYCLIN DEPENDENT KINASE INHIBITOR; MESSENGER RNA; NUCLEAR FACTOR I; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; DNA TRANSFECTION; DOSE RESPONSE; ENHANCER REGION; GENE REPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; MITOSIS INHIBITION; NORTHERN BLOTTING; PLASMID; PRIORITY JOURNAL; PROMOTER REGION;

4-BUTYROLACTONE; ALPHA-FETOPROTEINS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL DIVISION; CHLORAMPHENICOL O-ACETYLTRANSFERASE; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; G2 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; HUMANS; LIVER NEOPLASMS; MITOSIS; RNA, MESSENGER; SERUM ALBUMIN; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032409787     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Sherr CJ: Mammalian G1 cyclins. [Review] [84 refs]. Cell 73: 1059-1065, 1993.
2. Sherr CJ and Roberts JM: Inhibitors of mammalian G1 cyclin-dependent kinases. [Review] [153 refs]. Genes and Dev 9: 1149-1163, 1995.
3. Hinds PW and Weinberg RA: Tumor suppressor genes. [Review] [75 refs]. Curr Opin Genet Dev 4: 135-141, 1994.
4. Kitagawa M, Okabe T, Ogino H, Matsumoto H, Suzuki-Takahashi I, Kokubo T, Higashi H, Saitoh S, Taya Y and Yasuda H: Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase. Oncogene 8: 2425-2432, 1993.
5. Kitagawa M, Higashi H, Takahashi IS, Okabe T, Ogino H, Taya Y, Hishimura S and Okuyama A: A cyclin-dependent kinase inhibitor, butyrolactone I, inhibits phosphorylation of RB protein and cell cycle progression. Oncogene 9: 2549-2557, 1994.
6. Sato Y, Nakata K, Kato Y, Shima M, Ishii N, Koji T, Taketa K, Endo Y and Nagataki S: Early recognition of hepatocellular carcinoma based on altered profiles of alpha-fetoprotein. N Eng J Med 328: 1802-1806, 1993.
7. Nakata K, Khan KN and Nagataki S: Transcatheter arterial embolization of hepatic neoplasms. Crit Rev Oncol Hematol 13: 93-105, 1992.
8. Nakabayashi H, Taketa K, Yamane T, Miyazaki M, Miyano K and Sato J: Phenotypical stability of a human hepatoma cell line, HuH-7, in long- term culture with chemically defined medium. Gann 75: 151-158, 1984.
9. Carmichael J, DeGraff WG, Gazdar AF, Minna JD and Mitchell JB: Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47: 936-942, 1987.
10. Morinaga T, Sakai M, Wegmann TG and Tamaoki T: Primary structures of human alpha-fetoprotein and its mRNA. Proc Natl Acad Sci USA 80: 4604-4608, 1983.
11. Urano Y, Sakai M, Watanabe K and Tamaoki T: Tandem arrangement of the albumin and alpha-fetoprotein genes in the human genome. Gene 32: 255-261, 1984.
12. Watanabe K, Saito A and Tamaoki T: Cell-specific enhancer activity in a far upstream region of the human alpha-fetoprotein gene. J Biol Chem 262: 4812-4818, 1987.
13. Nakabayashi H, Watanabe K, Saito A, Otsuru A, Sawadaishi K and Tamaoki T: Transcriptional regulation of alpha-fetoprotein expression by dexamethasone in human hepatoma cells. J Biol Chem 264: 266-271, 1989.
14. Feigner PL, Gadek TR, Holm M, Roman R, Chan HW, Wenz M, Northrop JP, Ringold GM and Danielsen M: Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 84: 7413-7417, 1987.
15. German CM, Moffat LF and Howard BH: Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 2: 1044-1051, 1982.
16. Mendel DB and Crabtree GR: HNF-1, a member of a novel class of dimerizing homeodomain proteins. J Biol Chem 266: 677-680, 1991.
17. Feuerman MH, Godbout R, Ingram RS and Tilghman SM: Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1. Mol Cell Biol 9: 4204-4212, 1989.
18. Nahon JL, Danan JL, Poiret M, Tratner I, Jose-Estanyol M and Sala-Trepat JM: The rat alpha-fetoprotein and albumin genes. Transcriptional control and comparison of the sequence organization and promoter region. J Biol Chem 262: 12479-12487, 1987.
19. Zhang DE, Hoyt PR and Papaconstantinou J: Localization of DNA protein-binding sites in the proximal and distal promoter regions of the mouse alpha-fetoprotein gene. J Biol Chem 265: 3382-3391, 1990.
20. Nakata K, Motomura M, Nakabayashi H, Ido A and Tamaoki T: A possible mechanism of inverse developmental regulation of alpha-fetoprotein and albumin genes. Studies with epidermal growth factor and phorbol ester. J Biol Chem 267: 1331-1334, 1992.